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49 Cards in this Set
- Front
- Back
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Normal ICP
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5-15 mmHg
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What is the primary determinant of ICP
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increased CBF which increases CBV and ICP
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Intracranial HTN is defined as a Persistent elevation of ICP above?
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15 mmHg
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What is the best determinate of CBF
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PaCO2
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An increase in PaCO2 of 1 mmHg will increase CBF by?
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1 mmHg
*only if PaCO2 between 20-80 |
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What range do you want your PaCO2 in order to maximally decrease CBF
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25-35 mmHg
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a PaO2 _______causes increased CBF and ICP
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<50
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Normal CPP =
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80-100 mmHg
autoregulation = 50-150 mmHg |
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Hypothermia:
for every 1 Celcius decrease there is a decrease in CMRO2 by how much? |
7%
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CBF=
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45-54 ml/100gm/min
750 ml/min |
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Total CSF =
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150 ml, entire volume replaced 3-4 times/day
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Intracranial Components:
Brain tissues = % Blood = % CSF = % |
brain tissue = 80%
blood = 12% CSF = 8% |
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_______ ml/100g/min (CBF) can produce a flat EEG
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15-20
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Cerebral blood flow less than ______ is associated with irreversible brain damage
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<10
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CBF is proportional to PaCO2 -
-A change in CBF of ______ ml/100gm/min = ______PaCO2 change |
2 ml/100gm/min = 1 mmHg PaCO2 change
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Critical CPP is _______ mm Hg in the normal individual
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50
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Critical Pao2 is ____ to ______ in healthy awake patients
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30-35 mm hg
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How does hematocrit effect CBF
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a Hct of 32% - 34% increases CBF by decreasing viscosity, thereby improving oxygen delivery
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what two pharmacologic treatments are the only drugs shown to be effective for cerebral protection against ischemia
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barbs and erythropoietin
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Broca's area
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motor language
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Wernicke's area
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sensory language ( comprehension, word finding, making sense)
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Gray matter is found?
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cerebral cortex
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part of the brain responsible for movement and connections between thalamus and cortex
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basal ganglia
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contains 50% of neurons in brain but only 10% of mass....responsible for balance, equilibrium, muscle tone, voluntary muscle acitivty
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cerebellum
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Broca's area
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motor language
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CSF circulation = _____ ml/hr
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30 ml/hr
total volume = 150 ml |
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Wernicke's area
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sensory language ( comprehension, word finding, making sense)
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CSF production is decreased by:
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-decreased choroidal blood flow
-Hypothermia -Increased ICP -Increased serum osmolarity |
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Gray matter is found?
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cerebral cortex
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part of the brain responsible for movement and connections between thalamus and cortex
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basal ganglia
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Spinal cord extends to?
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L1-2
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How many segments in the spinal cord
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31
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contains 50% of neurons in brain but only 10% of mass....responsible for balance, equilibrium, muscle tone, voluntary muscle acitivty
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cerebellum
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CSF circulation = _____ ml/hr
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30 ml/hr
total volume = 150 ml |
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How many pairs of nerves
cervical: Thoracic: Lumbar: Sacral: Coccygeal: |
8 Cervical
12 Thoracic 5 Lumbar 5 sacral 1 coccygeal |
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CSF production is decreased by:
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-decreased choroidal blood flow
-Hypothermia -Increased ICP -Increased serum osmolarity |
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Broca's area
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motor language
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Spinal cord extends to?
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L1-2
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Wernicke's area
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sensory language ( comprehension, word finding, making sense)
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Gray matter is found?
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cerebral cortex
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How many segments in the spinal cord
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31
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part of the brain responsible for movement and connections between thalamus and cortex
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basal ganglia
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contains 50% of neurons in brain but only 10% of mass....responsible for balance, equilibrium, muscle tone, voluntary muscle acitivty
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cerebellum
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How many pairs of nerves
cervical: Thoracic: Lumbar: Sacral: Coccygeal: |
8 Cervical
12 Thoracic 5 Lumbar 5 sacral 1 coccygeal |
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CSF circulation = _____ ml/hr
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30 ml/hr
total volume = 150 ml |
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CSF production is decreased by:
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-decreased choroidal blood flow
-Hypothermia -Increased ICP -Increased serum osmolarity |
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Spinal cord extends to?
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L1-2
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How many segments in the spinal cord
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31
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How many pairs of nerves
cervical: Thoracic: Lumbar: Sacral: Coccygeal: |
8 Cervical
12 Thoracic 5 Lumbar 5 sacral 1 coccygeal |
