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19 Cards in this Set

  • Front
  • Back
connective tissue characteristics
consists of:
ground substance
-nutrients (O2) to tissues and bring back waste
-keep structures in place
-physical form (supporting)
-house fat cells (thermoregulation)
connective tissue cells
-plasma cells, lymphocytes, monocytes, neutorphils and eosinophils are wandering
Mesenchymal cells
-stem cells
Fibroblast and Fibrocyte
-most common cell in CT
-make collagen fibers (eosinophils)
Reticular cell
not reticulocyte
-stellate cells with spherical nucleus
-produce reticular fibers
basophilic cytoplasm
lymph nodes
bone marrow
Adipocyte/Adipose Cell
-large cells containing a single large non-membrane bound lipid droplet, peripheral nucleus, store energy
-central nucleus, many droplets, heat product
-elongated cell
adjacent to endothelial cell
contain contractile filaments
Mast cells
-near rb vessels
-central spherical nucleus
-granules: histamine, heparin, proteases
-mesenchymal precursor
-mobile or fixed
-originates from monocyte
-phagocytic cell
-cytoplasmic vacuoles, lysosomes, phagosomes, pseudopodia
-antigen presenting
Pigment cells
-Melanin containing cells in mammals
-common in dermis, uterine caruncles, meninges, melanocytes
Plasma Cells
-pear-shaped, ovoid or spherical cell
-peripheral spherical nucleus w/ cart wheel appearance
-basophilic (rER)
-develop from B-lymphocytes
Connective Tissue Fibers
Collagen Fibers
-principal fiber type
-high tensile strength, poor stretching and shearing
-digested by collagenase and serine-proteases
1. pro-a-chains form triple helix in rER
2. sent and packed in Golgi and exocytosed
3. cleavage of propeptides to form tropocollagen
4. tropocollagen assemble to or collagen fibrils
5. bundles of fibrils form collagen fibers
6. bundles of fibers form fasicles
Types of collagen
1.Fibril forming (123511)
propeptides cleaved
90% are type 1
2.Network forming (46)
not cleaved
associated with basal lamina
3. Fibril associated (912)
not cleaved
help interactions of fibrils w/ each other
Reticular Fibers
-cannot be distinguished from collagen
-individual collagen fibrils coated w. proteoglycans and glycoproteins
-scaffolding to support cells and cell groups
Elastic Fibers
-in organs requiring elasticity
-reflectile, wavy appearance, pink strands
-can stretch
-occur in single fibers that branch and anastomose
-ear, vocal cords, epiglotis, ligamentum nuchae, dermis, aorta, arteries
Fibrous Adhesive Proteins
-Fibronectin: fibril forming protein, binds various structures
-Laminin: large glycoprotein, attaches cells to basal lamina
Ground substance
-hydrated gel
-formed glycosaminoglycans (GAGs) and proteoglycans
-seven GAGs
Non sulfated: Hyaluronic acid
Sulfated: i.e. heparin