Connective Tissue

Front 1

What are the 6 types of human collagen, and where are they found?

Back 1

Type I: Bone, dentin, cementum
Type II: Cartilages
Type III = Reticular lamina
Type IV: Lamina densa
Type V: Found with type I AND in placenta
Type VII: Connects lamina densa to lamina reticularis

Front 2

What is hay fever?

Back 2

- Sneezing, etc. Mast cells release histamine via Ab-mediated response, irritating upper respiratory tract. Polyps, sinusitis
- CORTICOSTEROIDS counteract this

Front 3

What are macrophages?

Back 3

- Monocyte derived
- Phagocytose cells, debris
- KUPFFER cells in liver

Front 4

What are plasma cells?

Back 4

- Derived from b lymphocytes
- Secrete/produce Abs
- Basophilic, "clock face nucleus"

Front 5

What are mast cells?

Back 5

- Bone marrow derived
- B cell makes IgE at first Ag exposure --> attaches to mast
- 2nd exposure: IgE clusters, activating adenylate cyclase that causes degranulation and secretion

Front 6

What characterizes white adipose cells?

Back 6

- Unilocular (one drop)
- RECEPTORS for insulin, GH, norepinepherine, glucocorticoids --> uptake/release of glycerol/fatty acids
- HIGHLY VASCULARIZED

Front 7

What characterizes brown adipose cells?

Back 7

- Only in infants. Several drops
- Extensive mitochondria - activity generates warmth
-

Front 8

What is the funciton of adipose cells?

Back 8

- Synthesis, storage, release of fat
- Intestinal cells reesterify fatty acids to TRIGLYCERIDES
- ^ surrounded by proteins for transport
- At capillaries of adipose, VLDL (liver) and chylomicrons broken down by lipase, diffuse through cell membranes
- Cells reform triglycerides to add to lipid droplets

Front 9

What characterizes Loose (Areolar) CT

Back 9

- Gel like GS, loose arrangement of fibers
- LAMINA PROPRIA in mucous membranes
- Main inflammatory battlefield

Front 10

What characterizes Loose (Areolar) CT

Back 10

- Many fibers
- Dense irregular: dermis, capsule
- Dense regular: tendons/ligaments