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54 Cards in this Set
- Front
- Back
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Abdominal pain, ascites, hepatomegaly
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Budd- Chiari Syndrome (posthepatic venous thrombosis)
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Achilles tendon xanthoma
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Familial hypercholesterolemia
(decrease LDL receptor signaling) |
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Adrenal hemorrhage, hypotension, DIC
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Waterhouse-Friderichsen syndrome (meningococcemia)
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Arachnodactyle, lens dislocation, aortic dissection, hyperflexible joints
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Marfan's syndrome (fibrillin defect)
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Athlete with polycythemia
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Erythropoietin injection
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Back pain, fever, night sweats, weight loss
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Pott's disease (vertebral tuberculosis)
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Bilateral hilar adenopathy, uveitis
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Sarcoidosis (noncaseating granulomas)
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Blue sclera
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Osteogenesis imperfecta (collagen defect)
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Bluish line on gingiva
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Burton's line (lead poisoning)
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Bone pain, bone enlargement, arthritis
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Paget's disease of bone (increase osteoblastic and osteoclastic activity)
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Bounding pulses, diastolic heart murmur, head bobbing
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Aortic regurgitation
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"Butterfly" facial rash and Raynaud's phenomenon in a young female
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Systemic lupus erythematosus
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Cafe-au-lait spots, Lisch nodules (iris hamartoma)
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Neurofibromatosis type 1 (+ pheochromocytoma, optic gliomas) Neurofibromatosis type 2(+ bilateral acoustic neuromas)
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Cafe-au-lait spots, polyostotic fibrous dysplasia, precocious puberty
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McCune-Albright syndrome (mosaic G-protein signaling mutation)
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Calf pseudohypertrophy
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Muscular dystrophy (most commonly duchenne's): X-linked recessive deletion of dystrophin gene
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"Cherry-red spot" on macula
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Tay-Sachs (ganglioside accumulation) or Niemann-Pick (sphingomyelin accumulation),central retinal artery occlusion
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Chest pain on exertion
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Angina (stable: moderate exertion; unstable: minimal exertion)
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Chest pain, pericardial effusion/friction rub, persistent fever following MI
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Dressler's syndrome (autoimmune-mediated post-MI fibrinous pericarditis, 1-12 weeks after acute episode)
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Child uses arms to stand up from squat
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Gowers' sign (Duchenne muscular dystrophy)
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Child with fever develops red rash on face that spreads to body
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"Slapped Cheeks" (erythemia infectiosum/fifth disease: parvovirus B19)
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Chorea, dementia, caudate degeneration
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Huntington's disease (autosomal-dominant CAG repeat expansion)
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Chronic exercise intolerance with myalgia, fatigue, painful cramps, myoclobinuria
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McArdle's disease (muscle glycogen phosphorylase deficiency)
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Cold intolerance
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Hypothyroidism
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Conjugate lateral gaze palsy, horizontal diplopia
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Internuclear ophthalmoplegia (damage to MLF; bilateral [ multiple sclerosis], unilateral [stroke])
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Continuous "machinery" heart murmur
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PDA (close with indomethacin; open with misoprostol)
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Cutaneous/dermal edema due to connective tissue deposition
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Myxedema (caused by hypothyroidism, Graves' disease [periorbital])
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Dark purple skin/mouth nodules
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Kaposi's sarcoma (usually AIDS patients [gay men]: associated with HHV-8)
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Deep, labored breathing/hyperventilation
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Kussmaul breathing (diabetic ketoacidosis)
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Dermatitis, dementia, diarrhea
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Pellagra (niacin [vitamin B3] deficiency)
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Dilated cardiomyopathy, edema, polyneuropathy
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Wet beriberi (thiamine [vitamin B1] deficiency)
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Dog or cat bite resulting in infection
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Pasteurella multocida (cellulitis at inoculation site)
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Dry eyes, dry mouth, arthritis
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Sjogren's syndrome (autoimmune destruction of exocrine glands)
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Dysphagia (esophageal webs), glossitis, iron deficiency anemia
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Plummer-Vinson syndrome (may progress to esophageal squamous cell carcinoma)
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Elastic skin, hypermobility of joints
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Ehlers-Danlos syndrome (type 3 collagen defect)
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Enlarged, hard left supraclavicular node
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Virchow's node (abdominal metastasis)
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Erythroderma, lymphadenopathy, hepatosplenomegaly, atypical T cells
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Sezary syndrome (cutaneous T-cell lymphoma) or mycosis fungoides
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Facial muscle spasm upon tapping
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Chvostek's sign (hypocalcemia)
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Fat, female, forty, and fertile
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Acute cholelithiasis (bile duct blockage)
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Fever, chills, headache, myalgia following antibiotic treatment for syphilis
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Jarisch-Herxheimer reaction (rapid lysis of spirochetes results in toxin release)
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Fever, cough, conjunctivitis, coryza, diffuse rash
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Measles (Morbillivirus)
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Fever, night sweats, weight loss
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B symptoms (lymphoma)
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Fibrous plaques in soft tissue of penis
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Peyronie's disease (connective tissue disorder)
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Gout, mental retardation, self-mutilating behavior in a boy
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Lesch-Nyhan syndrome (HGPRT deficiency, X-linked recessive)
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Green-yellow rings around peripheral cornea
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Kayser-Fleischer rings (copper accumulation from Wilson's disease)
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Hamartomatous GI polyps, hyper pigmentation of mouth/feet/hands
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Peutz-Jeghers syndrome (genetic benign polyposis can cause bowel obstruction; increase cancer risk
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Hepatosplenomegaly,osteoporosis, neurologic symptoms
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Gaucher's disease (glucocerebrosidase deficiency)
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Hereditary nephritis, sensorineural hearing loss, cataracts
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Alport syndrome (mutation in alpha chain of collagen IV)
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Hypercoagulability (leading to migrating DVTs and vasculitis)
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Trousseau's sign (adenocarcinoma of pancreas or lung)
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Hyperphagia, hypersexuality, hyperorality, hyperdocility
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Kluver-Bucy syndrome (bilateral amygdala lesion)
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Hyperreflexia, hypertonia,positive Babinski sign
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UMN damage
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Hypertension, hypokalemia, metabolic alkalosis
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Conn's syndrome
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Hyporeflexia, hypotonia, atrophy
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LMN damage
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Hypoxemia, polycythemia, hypercapnia
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"Blue bloater" (chronic bronchitis: hyperplasia of mucous cells)
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Indurated, ulcerated genital lesion
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Nonpainful: chancre (primary syphilis, Treponema pallidum) Painful, with exudate: chancroid (Haemophilus ducreyi)
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