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149 Cards in this Set
- Front
- Back
The process by which certain cells engulf and digest microorganisms and cellular debris is called: |
phagocytosis |
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An examination in which the different kinds of white blood cells are counted and reported as percentages of the total examined or absolute (actual number) is called: |
differential white blood cell count |
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The element that makes up 55% of the blood is: |
plasma |
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anemia |
a disorder characterized by low levels of RBCs, hemoglobin, & hematocrit |
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aplasia |
failure of normal process of cell generation & development; also called aplastic anemia |
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pancytopenic |
all 3 major blood elements (red cells, white cells & platelets) from bone marrow are reduced or absent |
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disseminated intravascular coagulation (DIC) |
aquired hemmorrhage syndrome of clotting, cascade overstimulation & anticlotting processes |
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erythrocytosis |
an increase in circulating RBCs |
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erythropoiesis |
process of RBC prodution; occurs in bone marrow |
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hemarthrosis |
bleeding in the joint space; a hallmark of severe disease usually occurring in the knees, ankles, and elbow |
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hemophilia A |
hereditary coagulation disorder; caused by lack of antihemophilic factor VIII |
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heterozygous |
having two different genes |
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homozygous |
having two identical genes, inherited from each parent |
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leukemia |
malignant disorder; excess of leukocytes accumulates in bone marrow & lymph nodes |
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leukopenia |
abnormal decrease in the number of WBC to fewer than 5000 cells/mm3 due to depression of bone marrow |
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lymphangitis |
inflammation of one or more lymphatic vessels; results from strep or staph in an extremity |
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lymphedema |
accumulation of lymph in soft tissue and edema |
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multiple myeloma |
malignant neoplastic immunodeficiency disease of bone marrow; tumor composed of plasma cells; also called plasma cell myeloma |
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myeloproliferative |
excessive bone marrow production |
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pernicious |
capable of causing great injury or destruction; deadly, fatal |
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Reed-Sternberg cells |
atypical histocytes; large, abnormal, multinucleated cells in lymphatic system, found in Hodgkin's lymphoma |
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thrombocytopenia |
abnormal hematologic condition; platelets are less than 100,000/mm3 |
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Erythrocytes are also known as: |
red blood cells |
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Leukocytes are also known as: |
white blood cells; have nuclei, are colorless, & live from a few days to several years |
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neutrophils |
*WBCS that are the First Responders to scene*; the primary phagocytic cells; 60-70% |
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A mature neutrophil is called: |
a segmental neutrophil or "seg" |
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bandemia |
an increase in the number of band neutrophils |
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eosinophils |
WBCs involved in inflammatory response; neutralize histamine & destroy certain parasitic worms; normal values are 1%-4% |
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basophils |
WBCs that release histamine (vasodilator) during tissue damage or invasion; inhibits clot formation; normal values are 0.5% to 1% |
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monocytes |
WBCs that are second on the scence to an infection; engage in phagocytosis; normal values are 2%-6% |
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lymphocytes |
WBCs: |
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thrombocytes |
platelets; smallest cells in blood, produced in red bone marrow & assist in forming clots and hemostasis; life span of 5-9 days, 150,000-400,000 in number |
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prothrombin time (PT) |
lab test determining the rapidity of blood clotting; 11-12.5 seconds |
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partial thrombin time (PTT) |
lab test determining fibrin clot formation; 60-70 seconds |
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lymphatic system's functions |
maintenance of fluid balnce, production of lymphocytes & absorption and transportation of lipids from intestine to bloodstream |
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hematocrit |
lab test of the packed cell volume of RBCs; 42%-52% in men and 37%-47% in women |
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hemoglobin |
O2 carrying portion of RBC |
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renal erythropoietic factor |
an enzyme released by kidneys signaling the need for more O2 to blood, kickstarting RBC production in bone marrow |
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tonsils |
protect body from invasion of foreign substances by producing lymphocytes & antibodies |
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Which is a normal blood value for eosinophils? |
1% to 4% |
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Which is a normal blood value for lymphocytes? |
20% to 40% |
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The spleen stores how many milliliters of blood that can be released in emergencies? |
(500mL) 1 pint of blood |
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Pernicious anemia results from inadequate absorption of: |
B12 |
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Which nursing intervention does the nurse plan for a patient who has multiple myeloma? |
Increase fluid intake to 3000 to 4000 mL/day |
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When developing a care plan for a patient just diagnosed with leukemia, which two nursing diagnoses are the most appropriate to use? |
Risk for infection & ineffective coping |
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The patient has a history of iron deficiency anemia. The value most indicative of iron deficiency anemia is: |
RBC count and hemoglobin and hematocrit levels to be below normal; Normal hemoglobin level is 14 to 18 g/dL for males. |
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An oral iron supplement may turn the stool black. |
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The patient, age 35, is admitted with aplastic anemia. He asks the nurse what aplastic anemia is. An accurate response would be that: |
Aplastic anemia or aplasia (failure of the normal process of cell generation & development) is congenital & acquired. All three major blood elements (RBCs, WBCs, platelets) are reduced or absent. |
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A patient, an African American, is the mother of a 9-year-old child with sickle cell anemia. She asks the nurse if sickle cell anemia occurs frequently in her race. The correct response is that: |
Approx. 1 of every 10 African Americans (81%) has sickle cell traits, and approx. 1 of every 500-600 has sickle cell anemia. |
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The patient has agranulocytosis with a neutrophil count of 10%. The most important nursing intervention would be: |
Protecting the patient from infection because normal count is 60-70% |
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A patient, age 24, is admitted with idiopathic thrombocytopenic purpura and a platelet count of 18,000/mm3. An appropriate nursing intervention would be to: |
Significant risk for serious bleeding occurs when the count is below 20,000/mm3. |
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The nurse is caring for a 34-year-old obstetric patient who has disseminated intravascular coagulation (DIC). The nurse is aware that DIC is: |
a grave coagulopathy condition resulting from the overstimulation of clotting and anticlotting processes in response to disease or injury. |
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The appropriate nursing intervention to relieve the symptom of pruritus in a patient with Hodgkin’s disease would be: |
Soothing baths with an antipruritic medication (as ordered) can be effective. |
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A patient is admitted with fatigue; discomfort; enlarged, painless cervical lymph nodes; and pruritus. A lymph node biopsy yields a diagnosis of Hodgkin’s disease. The nurse is aware that the abnormal cells noted by the pathologist in Hodgkin’s disease are called: |
Reed-Sternberg cells |
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Patients with pernicious anemia must receive injections of which medication for the rest of their lives? |
1,000 units of B12 |
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A patient, age 52, is admitted with thrombocytopenia. The most important nursing intervention to prevent hemorrhage in this patient is to: |
Instruction to patient on s/sx, as well as preventive measures (stool softner, high fiber diet, soft toothbrush, blow nose gently), and notifying physican of s/sx of bleeding |
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Hematological diseases are often associated with skin impairment. Petechiae and ecchymoses are seen in: |
hemophilia A |
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The typical medical treatment of polycythemia vera involves: |
Repeated phlebotomy decreases blood viscosity |
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A patient, age 23, is admitted with enlarged lymph nodes, decreased production of RBCs, thrombocytopenia, and a severe increase in his WBC count. A bone-marrow aspiration shows abnormal lymphocytes present. These abnormalities are present in which disease? |
Bone marrow biopsy shows immature leukocytes. Chest radiographic examination may show mediastinal node and lung involvement and bone changes. Sickle cell anemia, hemophilia, and thrombocytopenia do not usually have elevated WBC count. |
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The patient, age 44, has polycythemia vera. The nurse recognizes that the primary pathophysiologic feature of this disorder is: |
Polycythemia vera is characterized by erythrocytosis (an abnormal increase in the number of circulating red blood cells) and also increased production of granulocytes and platelets. |
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Which should the nurse implement as the most important measure in preventing transmission of harmful pathogens to patients with depressed bone marrow function? |
Meticulous handwashing by medical and nursing personnel and strict asepsis are mandatory. |
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The average life span of an erythrocyte is: |
129 days |
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Life span of a WBC |
several days to several years |
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Life span of platelets |
5-9 days |
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Many older adults suffer from conditions such as colonic diverticula, hiatal hernia, and ulcerations that can cause occult bleeding. Older adults with these conditions should be observed for: |
iron deficiency |
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The nurse is administering a blood transfusion to an older adult for hypovolemic shock. During the transfusion, which nursing intervention would be the most important? |
Careful assessment of cardiopulmonary function and intake and output is essential. |
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If a patient is diagnosed with anemia, how are the tissues and cells affected? |
insufficient amounts of oxygen are delivered to tissues and cells. |
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Donors who are less likely to be adequate bone marrow transplant would include: |
twins, siblings, or self (autologous) while in remission are preferred. |
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The spleen is a highly vascularized organ located in the left upper quadrant of the abdominal cavity. The main functions of the spleen are: |
(1) to serve as a reservoir for blood; |
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_____________ are leukocytes which destroy and remove cellular waste, bacteria, and solid particles. |
Neutrophils |
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The organ that forms lymphocytes is the __________. |
spleen |
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A sudden reduction in blood volume may lead to _________ shock. |
hypovolemic |
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Replaces iron stores needed for RBC development |
ferrous sulfate |
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Needed for adequate nerve functioning |
B12 |
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Stimulates proliferation and differentiation of neutrophils |
Neupogen |
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Needed for erythropoiesis |
folic acid |
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Blood disorder characterized by red blood cell, hemoglobin, and hematrocrit levels below normal range |
anemia |
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In hematology, a failure of the normal process of cell geneneration and development |
aplasia |
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Acquired hemorrhage syndrome of clotting, cascade overstimulation, and anticlotting processes |
Disseminated intravascular coagulation (DIC) |
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Hereditary coagulation disorder; caused by a lack of antihemophilic factor VIII, which is needed to convert prothrombin to trhombin through thromboplastin component |
Hemophila A |
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The gland that plays a role in the development of the body's immune system is the: |
thymus |
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A shift to the left on the WBC differential indicates an increase in the number of: |
bands, or immature polymorphonuclear leukocytes |
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The universal recipient with regard to blood type is type: |
AB |
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The preferred diagnostic test for evaluating deep lymph nodes is: |
CT |
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Test used to diagnose sickle cell anemia |
peripheral smear |
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Test used to diagnose pernicious anemia |
Schilling test but being replaced by megaloblastic anemia profile; older test is gastric analysis |
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Your elderly patient has been diagnosed with pernicious anemia. You remember that this type of anemia results from:
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the absence of a glycoprotein intrinsic factor secreted by the gastric mucosa
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You are admitting a patient who has polycythemia to your unit. Which of the following patients best fits the profile of a patient with this disorder? |
A middle-aged male with elevated blood pressure and an erythematous appearance |
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The most severe risk for a patient with agranulocytosis is that of: |
infection |
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Your patient with leukemia is susceptible to hemorrhage. Which blood dyscrasia makes him susceptible to this?
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thrombocytopenia |
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You are caring for a patient with hemophilia. Which of the following nursing diagnoses would you expect to see on his nursing care plan? Select all that apply. |
Ineffective tissue perfusion Fluid volume deficit Anxiety Pain |
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Which of the following is the main diagnostic feature of Hodgkin s disease? |
Reed-Sternberg cells |
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A grave disease process in which the patient experiences both bleeding and intravascular clotting at the same time is known as: |
Disseminated intravascular coagulation (DIC) |
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A CBC includes: |
1. RBC and WBC |
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Common site for bone marrow aspiration or biopsy |
posterior iliac crest |
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What can cause anemia? |
1. hemorrhage |
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What can occur if there is a blood loss approaching 1000 mL? |
hypovolemic shock |
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What happens at a blood loss of 1500 to 2000 mL? |
irreversible end-organ damage |
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Subjective data of hypovolemic anemia |
1. thirst |
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cyanocobalamin |
B12 |
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What kind of virus is suspected to be the cause of Non-Hodgkin's Lymphoma? |
herpes-like |
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What kind of patients are at greater risk of developing Non-Hodgkin's Lymphoma? |
Pts who receive immunosuppressive agents; more common in men >60, whites & Jewish ancestry |
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What do they call the area that includes the chest wall, mediastinum, axillae, and neck? |
The mantle field |
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Objective data of Non-Hodgkin's Lymphoma |
1. splenomegaly |
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What is a useful system for classifying Non-Hodgkin's Lymphoma? |
The international working formulation; indolent (low grade), agressive (intermediate grade) & very aggressive (high grade) |
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Hodgkin's lymphoma occurs more frequently in people who have had _________________. |
mononucleosis |
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Even after a small amount of _____________, individuals with HL may complain of a rapid onset of pain at the site of the disease. |
alcohol |
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What kind of diet is recommended for pernicious anemia? |
high in vitamins, iron, and protein |
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To control pernicious anemia, what two things must the pt understand? |
1. disease process |
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iron deficiency anemia |
a condition in which the RBCs contain decreased levels of Hgb. |
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What amount of blood should be loss in the upper GI tract for stools to appear black or melenic. |
50 to 75 mL |
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What two diseases result in malabsorption of iron? |
Celiac disease and sprue |
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What are the two most common signs of iron deficiency anemia (in order)? |
pallor ----> glossitis |
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the desire to eat ice, clay, or starches |
pagophagia |
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What enhances iron absorption? |
ascorbic acid |
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Should you report black tarry stools? |
No, it is expected with iron therapy |
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What might a patient with polycythemia complain of b/c of engorgement of the spleen and liver? |
satiety (fullness) |
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Splenomegaly occurs in only ____________ polycythemia. |
primary |
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How do you prevent secondary polycythemia? |
adequate oxygenation |
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What is the major cause of morbidity and mortality in polycythemia vera? |
thrombosis |
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Name the three granulocytes |
B.E.N. |
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What are the two primary causes of agranuloctosis? |
1. medication reaction |
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A potentially fatal condition of the blood characterized by a severe reduction in the number of granulocytes |
agranulocytosis |
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ITP platelets are coated with _________ |
antibodies |
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What is the antihemophilic factor VIII for? |
conversion of prothrombin to thrombin |
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Exhibits a deficiency of factor IX with an absence of plasma thromoplastin component, resulting in nonformation of thromboplastin |
Hemophilia B (Christmas disease) |
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In hemophilia, who are usually the carriers? |
females (think Queen Victoria) |
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How do you treat chronic leg ulcers that result from sickle cell anemia? |
Bed rest, antibiotics, warm saline soaks, mechanical or enzyme debridement and dressings |
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sickle cell anemia |
an abnormal crescent-shapred RBC comtaining hemoglobin S (Hg-S), a defective hemoglobin molecule |
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sickle cell trait |
Heterozygous form of sickle cell anemia whereby the individual has both hemoglobin S (Hg-S) & hemoglobin A (Hg-A) in the RBCs. Pts. don't have s/sx but pass disorder to their children |
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What is the life span of an RBC affected by sickle cell disease? |
10-20 days |
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What is the primary symptom associated with sickle cell disease? |
pain |
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A myeloproliferative disorder with hyperplasia of bone marrow (too much); it manifests with an increase in circulating erythrocytes, granulocytes, and platelets. It develops gradually and is a chronic disease |
polycythemia vera |
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When doing an assessment on someone with polycythemia vera, what might you find? |
Patient complaints of sensitivity to hot and cold. Generalized pruritis, which is related to histamine release from an increased number of basophils. |
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What blood product replaces missing clotting factors in the client who has a bleeding disorder? |
Cryoprecipitate |
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methotrexate (Rheumatrex) |
antimetabolite med that treats ovarian & breast cancer. Also treats RA & lupus. |
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cyclophosphamide (Cytoxan) |
oldest catagory of antineoplastic meds that alter DNA's shape; may cause permanent infertility |
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bleomycin (Blenoxane) |
Antitumor antibiotic class; Treats Hodgkin's lymphoma & testicular cancer; may damage lung cells |
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iodine-125 |
radioactive isotope that targets tumors; swallowed or implanted |
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interferon alfa-2b |
treats leukemia, malignant melanoma, AIDS-related Kaposi's sarcoma & hepatitis B & C; stimulates blood cells important to immune system |
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vineblastine (Velban) |
aka mitotic inhibitors by preventing formation of mitotic spindle & cells cannot complete mitosis, causing cell death; organ, blood & lymph cancers |
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Nursing intervention that may benefit patient with nausea |
providing ice chips to hold in mouth |
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How effectiveness of antineoplastic agents are best evaluated |
lab studies |
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Healthy cells in this area of the body are commonly affected by antineoplastic agents |
gastrointestinal |
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Nursing diagnosis for patient taking antineoplastic meds |
deficient fluid volume (due to N/V, no appetite) |
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alopecia & bone marrow depression |
common adverse reactions associated with antineoplastic drugs |
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slow growing cell growth |
chemotherapeutic agents act on this |
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desmopressin acetate |
DDAVP; antidiuretic hormone in body; increases factor VIII, increasing platelet aggregation; assess pulse & BP when given SC |
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antitumor antibiotics |
bleomycin & dactinomycin specific to this class; treat testicular tumors, Hodgkin's lymphoma, organ tumors & soft tissue cancers; typical S/E plus cardiotoxicity & pneumonitis |