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149 Cards in this Set

  • Front
  • Back

The process by which certain cells engulf and digest microorganisms and cellular debris is called:

phagocytosis

An examination in which the different kinds of white blood cells are counted and reported as percentages of the total examined or absolute (actual number) is called:

differential white blood cell count

The element that makes up 55% of the blood is:

plasma

anemia

a disorder characterized by low levels of RBCs, hemoglobin, & hematocrit

aplasia

failure of normal process of cell generation & development; also called aplastic anemia

pancytopenic

all 3 major blood elements (red cells, white cells & platelets) from bone marrow are reduced or absent

disseminated intravascular coagulation (DIC)

aquired hemmorrhage syndrome of clotting, cascade overstimulation & anticlotting processes

erythrocytosis

an increase in circulating RBCs

erythropoiesis

process of RBC prodution; occurs in bone marrow

hemarthrosis

bleeding in the joint space; a hallmark of severe disease usually occurring in the knees, ankles, and elbow

hemophilia A

hereditary coagulation disorder; caused by lack of antihemophilic factor VIII

heterozygous

having two different genes

homozygous

having two identical genes, inherited from each parent

leukemia

malignant disorder; excess of leukocytes accumulates in bone marrow & lymph nodes

leukopenia

abnormal decrease in the number of WBC to fewer than 5000 cells/mm3 due to depression of bone marrow

lymphangitis

inflammation of one or more lymphatic vessels; results from strep or staph in an extremity

lymphedema

accumulation of lymph in soft tissue and edema

multiple myeloma

malignant neoplastic immunodeficiency disease of bone marrow; tumor composed of plasma cells; also called plasma cell myeloma

myeloproliferative

excessive bone marrow production

pernicious

capable of causing great injury or destruction; deadly, fatal

Reed-Sternberg cells

atypical histocytes; large, abnormal, multinucleated cells in lymphatic system, found in Hodgkin's lymphoma

thrombocytopenia

abnormal hematologic condition; platelets are less than 100,000/mm3

Erythrocytes are also known as:

red blood cells

Leukocytes are also known as:

white blood cells; have nuclei, are colorless, & live from a few days to several years

neutrophils

*WBCS that are the First Responders to scene*; the primary phagocytic cells; 60-70%

A mature neutrophil is called:

a segmental neutrophil or "seg"

bandemia

an increase in the number of band neutrophils

eosinophils

WBCs involved in inflammatory response; neutralize histamine & destroy certain parasitic worms; normal values are 1%-4%

basophils

WBCs that release histamine (vasodilator) during tissue damage or invasion; inhibits clot formation; normal values are 0.5% to 1%

monocytes

WBCs that are second on the scence to an infection; engage in phagocytosis; normal values are 2%-6%

lymphocytes

WBCs:
T cells-attack & destroy pathogens
B cells-produce antibodies & destroy bacteria
normal values 20-40%

thrombocytes

platelets; smallest cells in blood, produced in red bone marrow & assist in forming clots and hemostasis; life span of 5-9 days, 150,000-400,000 in number

prothrombin time (PT)

lab test determining the rapidity of blood clotting; 11-12.5 seconds

partial thrombin time (PTT)

lab test determining fibrin clot formation; 60-70 seconds

lymphatic system's functions

maintenance of fluid balnce, production of lymphocytes & absorption and transportation of lipids from intestine to bloodstream

hematocrit

lab test of the packed cell volume of RBCs; 42%-52% in men and 37%-47% in women

hemoglobin

O2 carrying portion of RBC

renal erythropoietic factor

an enzyme released by kidneys signaling the need for more O2 to blood, kickstarting RBC production in bone marrow

tonsils

protect body from invasion of foreign substances by producing lymphocytes & antibodies

Which is a normal blood value for eosinophils?

1% to 4%

Which is a normal blood value for lymphocytes?

20% to 40%

The spleen stores how many milliliters of blood that can be released in emergencies?

(500mL) 1 pint of blood

Pernicious anemia results from inadequate absorption of:

B12

Which nursing intervention does the nurse plan for a patient who has multiple myeloma?

Increase fluid intake to 3000 to 4000 mL/day

When developing a care plan for a patient just diagnosed with leukemia, which two nursing diagnoses are the most appropriate to use?

Risk for infection & ineffective coping

The patient has a history of iron deficiency anemia. The value most indicative of iron deficiency anemia is:

RBC count and hemoglobin and hematocrit levels to be below normal; Normal hemoglobin level is 14 to 18 g/dL for males.


A patient is to begin taking iron supplements. The nurse evaluates the patient’s understanding of the use of this drug. Which indicates that she has an adequate knowledge base?

An oral iron supplement may turn the stool black.

The patient, age 35, is admitted with aplastic anemia. He asks the nurse what aplastic anemia is. An accurate response would be that:

Aplastic anemia or aplasia (failure of the normal process of cell generation & development) is congenital & acquired. All three major blood elements (RBCs, WBCs, platelets) are reduced or absent.

A patient, an African American, is the mother of a 9-year-old child with sickle cell anemia. She asks the nurse if sickle cell anemia occurs frequently in her race. The correct response is that:

Approx. 1 of every 10 African Americans (81%) has sickle cell traits, and approx. 1 of every 500-600 has sickle cell anemia.

The patient has agranulocytosis with a neutrophil count of 10%. The most important nursing intervention would be:

Protecting the patient from infection because normal count is 60-70%

A patient, age 24, is admitted with idiopathic thrombocytopenic purpura and a platelet count of 18,000/mm3. An appropriate nursing intervention would be to:

Significant risk for serious bleeding occurs when the count is below 20,000/mm3.

The nurse is caring for a 34-year-old obstetric patient who has disseminated intravascular coagulation (DIC). The nurse is aware that DIC is:

a grave coagulopathy condition resulting from the overstimulation of clotting and anticlotting processes in response to disease or injury.

The appropriate nursing intervention to relieve the symptom of pruritus in a patient with Hodgkin’s disease would be:

Soothing baths with an antipruritic medication (as ordered) can be effective.

A patient is admitted with fatigue; discomfort; enlarged, painless cervical lymph nodes; and pruritus. A lymph node biopsy yields a diagnosis of Hodgkin’s disease. The nurse is aware that the abnormal cells noted by the pathologist in Hodgkin’s disease are called:

Reed-Sternberg cells

Patients with pernicious anemia must receive injections of which medication for the rest of their lives?

1,000 units of B12

A patient, age 52, is admitted with thrombocytopenia. The most important nursing intervention to prevent hemorrhage in this patient is to:

Instruction to patient on s/sx, as well as preventive measures (stool softner, high fiber diet, soft toothbrush, blow nose gently), and notifying physican of s/sx of bleeding

Hematological diseases are often associated with skin impairment. Petechiae and ecchymoses are seen in:

hemophilia A

The typical medical treatment of polycythemia vera involves:

Repeated phlebotomy decreases blood viscosity

A patient, age 23, is admitted with enlarged lymph nodes, decreased production of RBCs, thrombocytopenia, and a severe increase in his WBC count. A bone-marrow aspiration shows abnormal lymphocytes present. These abnormalities are present in which disease?

Bone marrow biopsy shows immature leukocytes. Chest radiographic examination may show mediastinal node and lung involvement and bone changes. Sickle cell anemia, hemophilia, and thrombocytopenia do not usually have elevated WBC count.

The patient, age 44, has polycythemia vera. The nurse recognizes that the primary pathophysiologic feature of this disorder is:

Polycythemia vera is characterized by erythrocytosis (an abnormal increase in the number of circulating red blood cells) and also increased production of granulocytes and platelets.

Which should the nurse implement as the most important measure in preventing transmission of harmful pathogens to patients with depressed bone marrow function?

Meticulous handwashing by medical and nursing personnel and strict asepsis are mandatory.

The average life span of an erythrocyte is:

129 days

Life span of a WBC

several days to several years

Life span of platelets

5-9 days

Many older adults suffer from conditions such as colonic diverticula, hiatal hernia, and ulcerations that can cause occult bleeding. Older adults with these conditions should be observed for:

iron deficiency

The nurse is administering a blood transfusion to an older adult for hypovolemic shock. During the transfusion, which nursing intervention would be the most important?

Careful assessment of cardiopulmonary function and intake and output is essential.

If a patient is diagnosed with anemia, how are the tissues and cells affected?

insufficient amounts of oxygen are delivered to tissues and cells.

Donors who are less likely to be adequate bone marrow transplant would include:

twins, siblings, or self (autologous) while in remission are preferred.

The spleen is a highly vascularized organ located in the left upper quadrant of the abdominal cavity. The main functions of the spleen are:

(1) to serve as a reservoir for blood;
(2) to form lymphocytes, monocytes, and plasma cells;
(3) to destroy worn-out RBCs;
(4) to remove bacteria by phagocytosis (engulfing and digesting);
(5) to produce RBCs before birth (the spleen is believed to produce RBCs after birth only in cases of extreme hemolytic anemia).

_____________ are leukocytes which destroy and remove cellular waste, bacteria, and solid particles.

Neutrophils

The organ that forms lymphocytes is the __________.

spleen

A sudden reduction in blood volume may lead to _________ shock.

hypovolemic

Replaces iron stores needed for RBC development

ferrous sulfate

Needed for adequate nerve functioning

B12

Stimulates proliferation and differentiation of neutrophils

Neupogen

Needed for erythropoiesis

folic acid

Blood disorder characterized by red blood cell, hemoglobin, and hematrocrit levels below normal range

anemia

In hematology, a failure of the normal process of cell geneneration and development

aplasia

Acquired hemorrhage syndrome of clotting, cascade overstimulation, and anticlotting processes

Disseminated intravascular coagulation (DIC)

Hereditary coagulation disorder; caused by a lack of antihemophilic factor VIII, which is needed to convert prothrombin to trhombin through thromboplastin component

Hemophila A

The gland that plays a role in the development of the body's immune system is the:

thymus


A shift to the left on the WBC differential indicates an increase in the number of:

bands, or immature polymorphonuclear leukocytes


The universal recipient with regard to blood type is type:

AB


The preferred diagnostic test for evaluating deep lymph nodes is:

CT

Test used to diagnose sickle cell anemia

peripheral smear

Test used to diagnose pernicious anemia

Schilling test but being replaced by megaloblastic anemia profile; older test is gastric analysis

Your elderly patient has been diagnosed with pernicious anemia. You remember that this type of anemia results from:




the absence of a glycoprotein intrinsic factor secreted by the gastric mucosa


You are admitting a patient who has polycythemia to your unit. Which of the following patients best fits the profile of a patient with this disorder?

A middle-aged male with elevated blood pressure and an erythematous appearance



The most severe risk for a patient with agranulocytosis is that of:

infection

Your patient with leukemia is susceptible to hemorrhage. Which blood dyscrasia makes him susceptible to this?


thrombocytopenia

You are caring for a patient with hemophilia. Which of the following nursing diagnoses would you expect to see on his nursing care plan? Select all that apply.


Ineffective tissue perfusion


Fluid volume deficit


Anxiety


Pain

Which of the following is the main diagnostic feature of Hodgkin s disease?

Reed-Sternberg cells

A grave disease process in which the patient experiences both bleeding and intravascular clotting at the same time is known as:

Disseminated intravascular coagulation (DIC)

A CBC includes:

1. RBC and WBC
2. hematocrit
3. hemoglobin
4. erythrocyte indexes
5. Differential WBC
6. exam of peripheral blood cells

Common site for bone marrow aspiration or biopsy

posterior iliac crest

What can cause anemia?

1. hemorrhage
2. bone marrow depression
3. long-term iron deficiency


What can occur if there is a blood loss approaching 1000 mL?

hypovolemic shock


What happens at a blood loss of 1500 to 2000 mL?

irreversible end-organ damage

Subjective data of hypovolemic anemia

1. thirst
2. weakness
3. irritability
4. restlessness

cyanocobalamin

B12


What kind of virus is suspected to be the cause of Non-Hodgkin's Lymphoma?

herpes-like

What kind of patients are at greater risk of developing Non-Hodgkin's Lymphoma?

Pts who receive immunosuppressive agents; more common in men >60, whites & Jewish ancestry


What do they call the area that includes the chest wall, mediastinum, axillae, and neck?

The mantle field

Objective data of Non-Hodgkin's Lymphoma

1. splenomegaly
2. Enlarged lymph nodes
3. fever, night sweats, and weight loss


What is a useful system for classifying Non-Hodgkin's Lymphoma?

The international working formulation; indolent (low grade), agressive (intermediate grade) & very aggressive (high grade)


Hodgkin's lymphoma occurs more frequently in people who have had _________________.

mononucleosis


Even after a small amount of _____________, individuals with HL may complain of a rapid onset of pain at the site of the disease.

alcohol

What kind of diet is recommended for pernicious anemia?

high in vitamins, iron, and protein

To control pernicious anemia, what two things must the pt understand?

1. disease process
2. importance of lifetime therapy of vitamin B12

iron deficiency anemia

a condition in which the RBCs contain decreased levels of Hgb.


What amount of blood should be loss in the upper GI tract for stools to appear black or melenic.

50 to 75 mL


What two diseases result in malabsorption of iron?

Celiac disease and sprue


What are the two most common signs of iron deficiency anemia (in order)?

pallor ----> glossitis


the desire to eat ice, clay, or starches

pagophagia

What enhances iron absorption?

ascorbic acid


Should you report black tarry stools?

No, it is expected with iron therapy


What might a patient with polycythemia complain of b/c of engorgement of the spleen and liver?

satiety (fullness)


Splenomegaly occurs in only ____________ polycythemia.

primary


How do you prevent secondary polycythemia?

adequate oxygenation


What is the major cause of morbidity and mortality in polycythemia vera?

thrombosis

Name the three granulocytes

B.E.N.
basophils
eosinophils
neutrophils


What are the two primary causes of agranuloctosis?

1. medication reaction
2. toxicity


A potentially fatal condition of the blood characterized by a severe reduction in the number of granulocytes

agranulocytosis

ITP platelets are coated with _________

antibodies

What is the antihemophilic factor VIII for?

conversion of prothrombin to thrombin

Exhibits a deficiency of factor IX with an absence of plasma thromoplastin component, resulting in nonformation of thromboplastin

Hemophilia B (Christmas disease)


In hemophilia, who are usually the carriers?

females (think Queen Victoria)

How do you treat chronic leg ulcers that result from sickle cell anemia?

Bed rest, antibiotics, warm saline soaks, mechanical or enzyme debridement and dressings

sickle cell anemia

an abnormal crescent-shapred RBC comtaining hemoglobin S (Hg-S), a defective hemoglobin molecule

sickle cell trait

Heterozygous form of sickle cell anemia whereby the individual has both hemoglobin S (Hg-S) & hemoglobin A (Hg-A) in the RBCs. Pts. don't have s/sx but pass disorder to their children

What is the life span of an RBC affected by sickle cell disease?

10-20 days

What is the primary symptom associated with sickle cell disease?

pain


A myeloproliferative disorder with hyperplasia of bone marrow (too much); it manifests with an increase in circulating erythrocytes, granulocytes, and platelets. It develops gradually and is a chronic disease

polycythemia vera

When doing an assessment on someone with polycythemia vera, what might you find?


Patient complaints of sensitivity to hot and cold. Generalized pruritis, which is related to histamine release from an increased number of basophils.

What blood product replaces missing clotting factors in the client who has a bleeding disorder?

Cryoprecipitate

methotrexate (Rheumatrex)

antimetabolite med that treats ovarian & breast cancer. Also treats RA & lupus.

cyclophosphamide (Cytoxan)

oldest catagory of antineoplastic meds that alter DNA's shape; may cause permanent infertility

bleomycin (Blenoxane)

Antitumor antibiotic class; Treats Hodgkin's lymphoma & testicular cancer; may damage lung cells

iodine-125

radioactive isotope that targets tumors; swallowed or implanted

interferon alfa-2b

treats leukemia, malignant melanoma, AIDS-related Kaposi's sarcoma & hepatitis B & C; stimulates blood cells important to immune system

vineblastine (Velban)

aka mitotic inhibitors by preventing formation of mitotic spindle & cells cannot complete mitosis, causing cell death; organ, blood & lymph cancers

Nursing intervention that may benefit patient with nausea

providing ice chips to hold in mouth

How effectiveness of antineoplastic agents are best evaluated

lab studies

Healthy cells in this area of the body are commonly affected by antineoplastic agents

gastrointestinal

Nursing diagnosis for patient taking antineoplastic meds

deficient fluid volume (due to N/V, no appetite)

alopecia & bone marrow depression

common adverse reactions associated with antineoplastic drugs

slow growing cell growth

chemotherapeutic agents act on this

desmopressin acetate

DDAVP; antidiuretic hormone in body; increases factor VIII, increasing platelet aggregation; assess pulse & BP when given SC

antitumor antibiotics

bleomycin & dactinomycin specific to this class; treat testicular tumors, Hodgkin's lymphoma, organ tumors & soft tissue cancers; typical S/E plus cardiotoxicity & pneumonitis