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13 Cards in this Set

  • Front
  • Back

What constitutes an Organ?

Two or more kinds of tissues grouped together and performing specialized functions.

What are the functions of the Skin? (9)

* Protective covering * Maintains homeostasis


* Prevents water loss * Thermoregulation


* Synthesizes chemical *Secretes


* Excretes small amounts of waste


* Sensation * Immune system cells

Describe the Epidermis. (3)

* Keratinized stratified squamous epithelium


* Four cells types


* Four or five distinct layers

What are the four cell types found in the Epidermis?

* Keratinocytes


* Melanocytes


* Dendritic cells


* Tactile cells

Describe Keratinocytes. (3)

* Most epidermal cells


* Produce Keratin


* Fibrous protein that gives the epidermis its protective properties

Describe Melanocytes. (2)

* Spider shaped epithelial cells that synthesize melanin


* Found in the deepest layer of the epidermis

Describe Dendritic cells. (4)

* Star shaped


* Arise from bone marrow and migrate to the epidermis


* Also called Langerhans cells


* Form a continuous network

Describe Tactile cells. (5)

* Shaped like a spiky hemisphere


* Present at the epidermal-dermal junction


* Also called Merkel cells


* Each is intimately associated with a disc-like sensory ending


* Sensory receptor for touch

What are the four layers of the Epidermis, from the bottom up?

* Stratum Basale


* Stratum Spinosum


* Stratum Granulosum


* Stratum Corneum

Describe the Stratum Basale. (3)

* One row of actively miotic stem cells


* Some newly formed cells become part of the more superficial layers


* Occasionally have melanocytes & dendritic cells

Describe the Stratum Spinosum. (2)

* Several layers of Keratinocytes unified by desmosomes


* Contain thick bundles of intermediate filaments made of pre-keratin

Describe the Stratum Granulosum. (3)

* 5 layers of flattened cells


* Organelles deteriorating


* Cytoplasm full of lamellar granules (which release lipids) and keratohyaline granules

Describe the Stratum Coreum (4)

* Top layer


* 20-30 layers of dead cells


* Flat membranous sacs filled with keratin


* Glycolipids in ECM