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47 Cards in this Set
- Front
- Back
what are the symptoms of pseudomonas auriginosa infection
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- change in tissue color
- chills, fever, skin lesions and shock - cauused by bacterial infection in bloodstream |
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- motile by means of single polar flagellum
- generally aerobic - can grow anaerobically in the presence of nitrate |
pseudomonas aeruginosa
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produces numerous water soluble pigments
- pigments combine to produce color change in tissues |
pseudomonas aeruginosa
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what are the early symptoms of tetanus
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- restlessness
- irritibility - difficulty swallowing - contraction of jaw muscles - convulsions - particularly in children |
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what are the early symptoms of tetanus
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- increased muscle involvement
- pain - difficulty breathing - death |
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what causes pain with tetanus
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more muscle involvement creates more severe pain
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what causes difficulty with breathing with tetanus
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the development of pneumonia
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what causes death with tetanus
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- pneumonia
- regurgitation of stomach contents into lungs |
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what is the causative agent of tetanus
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clostridium tetani
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- anaerobic
- gm + - bacillus - spore former - swarming growth on lab media |
c. tetani
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produces spherical spores instead of oval spores produced by other bacteria of the genus
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clostridium tetani
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- begin abruptly
- rapidly increase pain - increased swelling - thin bloody fluid leaks from wound |
clostridial myonecrosis
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- skin becomes stretched and mottled with black spots
- patient appears very ill but alert |
clostridial myonecrosis
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what is the most common cause of clostridial myonecrosis
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c. perfringens
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- encapsulated
- gm + rods - produce spores |
c. perfingens
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what 2 factors foster the development of clostridial myenecrosis
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- presence of dirt and dead tissue in wound
- long delays in treatment |
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what are som symptoms of staph wound infections
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- bacteria are pyogenic (pus)
- inflammation - fever in cases where infection has spread - some strains produce toxic shock syndrome |
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- gm + cocci
- grow aerobically or anaerobically (facultative) - salt tolerant |
staphylococci
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what strains of staph are most inportant and easily transfer from person to person
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s. aureus
e. epidermidis |
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- virulence due to production of extracellular products
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s. aureus
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- coagulase
- clumping factor - protein A - alpha toxin |
s. aureus
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causes blood clotting to evade phagocytosis
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s. aureus coagulase
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aids in bacterial wound colonization
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s. aureus clumping factor
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hide bacteria from phagocytic cells
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s. aureus protein A
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produces hole in host cell membrane
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s. aureus alpha toxin
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bacteria have little or no invasive ability in staph wound infections
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s. epidermidis
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- maintained on skin surface
- introduced into body from wound - internalized strain bind and allow colonization of indwelling devices |
s. epidermidis
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what are the symptoms of group A strep infections
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- acute pain at site of wound
- swelling - fever and confusion - overlying skin tightens and becomes discolored - shock and death |
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what happens in the absence of treatment in group A strep infections
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shock and death
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- group A lancefield cell wall polysaccharide
- some strains cause invasive infection two extracellular products are responsible for virulence |
s. pyogenes
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what are the two extracellular products of s. pyogenes that are responsible for virulence
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pyrogenicexotoxin A
exotoxin B |
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acts as a superantigen and causes streptococcal toxic shock
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pyrogenic exotoxin A
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destroys tissue through protein breakdown
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exotoxin B
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what are the symptoms of actinomycosis
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- lumpy jaw
- progresses slowly - sometimes includes painful swelling under the skin - swollen regions open and drain pus most cases involve the jaw or neck - scars and swelling give rise to name "lumpy jaw" |
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- openings usually heal
- lesions reappear at the same or nearby region within days oe weeks - recurring lesions may develop on chest and abdominal wall or genital tract of women |
actinomycosis
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what is the causative agent of actinomycosis
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actinomyces israelii
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- gm +
- filamentous - branching - anaerobic - slow growing - rod |
actinomyces israelii
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what are the symptoms of pastuerella multocida
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- no reliable symptoms that distinguish one bite from another
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what are the generalized symptoms of pastuerella multocida
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- spreading redness
- tenderness - swelling of adjacent tissues - pus discharge |
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- gm -
- facultative anaerobe - coccobacillus - most are encapsulated |
pastuerella multocida
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what is the pathogenicity of pastuerella multocida
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- details unknown
- some strains produce toxin * pus often foul smelling - capsules resist phagocytosis |
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what are the symptoms of cat scratch disease
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- disease begins within a week of scratch or bite
- development of pus filled pimple - painful enlargement of lymph nodes - fever |
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- nodes at region of wound enlarge in 1-7 weeks
- in about 50% or patients, nodes become pus filled |
cat scratch disease
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what is the causative agent of cat scratch disease
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bartonella henselae
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- gm - bacilli
- slightly curved |
bartonella henselae
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what are the symptoms of human bites
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- wound may appear insignificant
- painful with massive swelling - pus discharge - most wounds are on exterior of hand - bactorella - bacteridis |
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often foul smelling
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pus discharge in human bites
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