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47 Cards in this Set

  • Front
  • Back
what are the symptoms of pseudomonas auriginosa infection
- change in tissue color
- chills, fever, skin lesions and shock
- cauused by bacterial infection in bloodstream
- motile by means of single polar flagellum
- generally aerobic
- can grow anaerobically in the presence of nitrate
pseudomonas aeruginosa
produces numerous water soluble pigments

- pigments combine to produce color change in tissues
pseudomonas aeruginosa
what are the early symptoms of tetanus
- restlessness
- irritibility
- difficulty swallowing
- contraction of jaw muscles
- convulsions - particularly in children
what are the early symptoms of tetanus
- increased muscle involvement
- pain
- difficulty breathing
- death
what causes pain with tetanus
more muscle involvement creates more severe pain
what causes difficulty with breathing with tetanus
the development of pneumonia
what causes death with tetanus
- pneumonia

- regurgitation of stomach contents into lungs
what is the causative agent of tetanus
clostridium tetani
- anaerobic
- gm +
- bacillus
- spore former
- swarming growth on lab media
c. tetani
produces spherical spores instead of oval spores produced by other bacteria of the genus
clostridium tetani
- begin abruptly
- rapidly increase pain
- increased swelling
- thin bloody fluid leaks from wound
clostridial myonecrosis
- skin becomes stretched and mottled with black spots

- patient appears very ill but alert
clostridial myonecrosis
what is the most common cause of clostridial myonecrosis
c. perfringens
- encapsulated
- gm + rods
- produce spores
c. perfingens
what 2 factors foster the development of clostridial myenecrosis
- presence of dirt and dead tissue in wound

- long delays in treatment
what are som symptoms of staph wound infections
- bacteria are pyogenic (pus)

- inflammation
- fever in cases where infection has spread
- some strains produce toxic shock syndrome
- gm + cocci
- grow aerobically or anaerobically (facultative)
- salt tolerant
staphylococci
what strains of staph are most inportant and easily transfer from person to person
s. aureus
e. epidermidis
- virulence due to production of extracellular products
s. aureus
- coagulase
- clumping factor
- protein A
- alpha toxin
s. aureus
causes blood clotting to evade phagocytosis
s. aureus coagulase
aids in bacterial wound colonization
s. aureus clumping factor
hide bacteria from phagocytic cells
s. aureus protein A
produces hole in host cell membrane
s. aureus alpha toxin
bacteria have little or no invasive ability in staph wound infections
s. epidermidis
- maintained on skin surface
- introduced into body from wound
- internalized strain bind and allow colonization of indwelling devices
s. epidermidis
what are the symptoms of group A strep infections
- acute pain at site of wound
- swelling
- fever and confusion
- overlying skin tightens and becomes discolored
- shock and death
what happens in the absence of treatment in group A strep infections
shock and death
- group A lancefield cell wall polysaccharide
- some strains cause invasive infection two extracellular products are responsible for virulence
s. pyogenes
what are the two extracellular products of s. pyogenes that are responsible for virulence
pyrogenicexotoxin A
exotoxin B
acts as a superantigen and causes streptococcal toxic shock
pyrogenic exotoxin A
destroys tissue through protein breakdown
exotoxin B
what are the symptoms of actinomycosis
- lumpy jaw
- progresses slowly
- sometimes includes painful swelling under the skin
- swollen regions open and drain pus
most cases involve the jaw or neck
- scars and swelling give rise to name "lumpy jaw"
- openings usually heal
- lesions reappear at the same or nearby region within days oe weeks
- recurring lesions may develop on chest and abdominal wall or genital tract of women
actinomycosis
what is the causative agent of actinomycosis
actinomyces israelii
- gm +
- filamentous
- branching
- anaerobic
- slow growing
- rod
actinomyces israelii
what are the symptoms of pastuerella multocida
- no reliable symptoms that distinguish one bite from another
what are the generalized symptoms of pastuerella multocida
- spreading redness
- tenderness
- swelling of adjacent tissues
- pus discharge
- gm -
- facultative anaerobe
- coccobacillus
- most are encapsulated
pastuerella multocida
what is the pathogenicity of pastuerella multocida
- details unknown
- some strains produce toxin
* pus often foul smelling
- capsules resist phagocytosis
what are the symptoms of cat scratch disease
- disease begins within a week of scratch or bite
- development of pus filled pimple
- painful enlargement of lymph nodes
- fever
- nodes at region of wound enlarge in 1-7 weeks
- in about 50% or patients, nodes become pus filled
cat scratch disease
what is the causative agent of cat scratch disease
bartonella henselae
- gm - bacilli
- slightly curved
bartonella henselae
what are the symptoms of human bites
- wound may appear insignificant
- painful with massive swelling
- pus discharge
- most wounds are on exterior of hand
- bactorella
- bacteridis
often foul smelling
pus discharge in human bites