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117 Cards in this Set

  • Front
  • Back
What are the 5 classes of blood vessels? And what do they do?
1. Arteries:carry blood away from heart
2. Arterioles:smallest branches of arteries
3. Capillaries: smallest blood vessels, location of exchange between blood and interstitial fluid
4. Venules: collect blood from capillaries
Veins: return blood to heart
What are the largest blood vessels? And what do they do?
Pulmonary trunk: carries blood from right ventricle to pulmonary circulation
Aorta: carries blood from left ventricle to systemic circulation
What are the smallest blood vessels?
Capillaries

Have small diameter and thin walls
Chemicals and gases diffuse across walls
Arteries and veins have 3 wall laters, what are they?
tunica intima: inner layer
tunica media: middle layer
tunica externa: outer layer
What are the differences between arteries and veins?
They run side by side
Arteries have thicker walls and higher blood pressure
Arteries have small, round lumen...Vein has a large, flat lumen
Arteries more elastic
Vein lining contracts, artery lining doesn't
Veins have valves
What is vasoconstriction?
The contraction of arterial smooth muscle by the ANS
What is vasodilation?
Relaxes smooth muscle
Enlarging the lumen
What do vasoconstriction and vasodilation affect?
1. afterload on heart
2. peripheral blood pressure
3. capillary blood flow
How do arteries change from heart to capillaries?
from elastic arteries, to muscular arteries, to arterioles
What are elastic arteries?
Also called conducting arteries
Large vessels
Tunica media has many elastic fibers and few muscle cells
Elasticity evens out pulse force
What are muscular arteries?
Also called distribution arteries
medium-sized (most arteries)
Tunica media has many muscle cells
What are arterioles?
small
Have little or no tunica externa
Have thin or incomplete tunica media
What is resistance? And what vessels do this?
The force opposing blood flow
Arterioles do this
What is an aneurysm?
A bulge in an arterial wall that is caused by weak spot in elastic fibers.
Pressure may rupture vessel
What are capillaries?
Are smallest vessels with thin walls
What is the function of capillaries?
Location of all exchange functions of cardiovascular system
What is the structure of a capillary?
Endothelial tube, inside thin basal lamina
No tunica media
No tunica externa
Diameter is similar to red blood cell
What are the types of capillaries?
Continuous capillaries
Fenestrated capillaries
What are continuous capillaries and where are they found?
Have complete endothelial lining. Found in all tissues except epithelia and cartilage.
What are the functions of continuous capillaries?
Permit diffusion of:
water
small solutes
Lipid-soluble materials

Block:
blood cells
plasma proteins
What are fenestrated capillaries? And where are they found?
Have pores in endothelial lining
Found in:
choroid plexus
endocrine organs
kidneys
intestinal tract
What are the functions of fenestrated capillaries?
Permit rapid exchange of water and larger solutes
What is a Capillary Sphincter?
Guards entrance to each capillary
Opens and closes, causing capillary blood to flow in pulses
What are the 3 categories of veins?
1. Venules: very small veins
collect blood from capillaries
2. Medium-sized veins: thin tunica media
3. Large veins: have all 3 tunica layers
What are vein valves?
Folds of tunica intima
Prevent blood from flowing backward
What percent blood volume does the heart, arteries, and capillaries make up?
30-35%
The venous system makes up what percent of blood?
60-65%
What is capacitance?
The ability to stretch
Which stretch more, veins or arteries?
Veins
How do veins respond to blood loss?
Vasomotor centers stimulate sympathetic nerves...
-systemic veins constrict
- veins in liver, skin and lungs redistribute venous reserve
What is the term for when systemic veins constrict?
venoconstriction
What is capillary blood flow?
Equals cardiac output
Is determined by: pressure and resistance in the cardiovascular system
What is pressure?
What the heart generates to overcome resistance
What is the pressure gradient?
the difference between pressure at the heart and pressure at peripheral capillary beds
What are the different kinds of measuring pressures?
Blood pressure (BP): arterial pressure
Capillary hydrostatic pressure (CHP): pressure within the capillary beds
Venous pressure: pressure in the venous system
What is vascular resistance?
Resistance of blood vessels due to friction between blood and vessel walls
What is viscosity?
Resistance caused by molecules and suspended materials in a liquid
What is turbulance?
Swirling action that disturbs smooth flow of liquid
What are the different kinds of pressures in the systemic circuit?
Systolic pressure, Diastolic pressure, Pulse pressure, Mean arterial pressure
What is systolic pressure?
peak arterial pressure during ventricular systole
What is Diastolic pressure?
minimum arterial pressure during diastole
What is Pulse pressure?
difference between systolic pressure and diastolic pressure
What is Mean arterial pressure?
MAP = diastolic pressure + 1/3 pulse pressure
What is Hypertension?
abnormally high blood pressure
What is Hypotension?
abnormally low blood pressure
What happens to arterial walls during elastic rebound?
stretch during systole
rebound during diastole
keep blood moving during diastole
Blood pressure decreases with what?
Friction
Pulse pressure increases or decreases due to elastic rebound?
decreases
What is the venous return?
Amount of blood arriving at right atrium each minute
Compression of skeletal muscles....
pushes blood toward heart
What cavity is the Respiratory Pump in? What affect does inhaling and exhailing have?
Thoracic cavity
Inhaling decreases thoracic pressure
Exhaling raises thoracic pressure
What is Capillary Exchange?
Moves materials across capillary walls
What is Diffusion?
Movement of ions or molecules from high concentration to lower concentration
What are the 5 diffusion routes?
1. Water, ions, small molecules: diffuse between adjacent endothelial cells or fenestrated capillaries
2. Some other ions: diffuse through channels in cell membranes
3. Large, water-soluble compounds: pass through fenestrated capillaries
4. Lipids and lipid-soluble materials:
diffuse through endothelial cell membranes
5. Plasma proteins: cross endothelial lining in sinusoids
What is Filtration?
removal of large solutes through membrane
What is Capillary Filtration?
Water and small solutes forced through capillary wall, leaving larger solutes in bloodstream
What is Reabsorption the result of?
Osmosis
What does Osmotic pressure do?
equals pressure required to prevent osmosis
What does Hydrostatic pressure do?
forces water out of solution
What does Osmotic pressure do?
forces water into solution
What is Net Hydrostatic Pressure the difference between? And what does it do to water/solutes?
capillary hydrostatic pressure (CHP)
and interstitial fluid hydrostatic pressure (IHP)
Pushes water and solutes out of capillaries and into interstitial fluid
During capillary exchange, what happens at the arterial end of capillary
fluid moves out of capillary into interstitial fluid
During capillary exchange, what happens at the venous end of capillary?
fluid moves into capillary out of interstitial fluid
The transition point is between filtration and reabsorption; which end is it closer to: venous or arterial?
venous
What is Fluid Recycling?
When water moves out of capillaries and into bloodstream thru lymphatic system
What are the 4 Functions of Blood and Lymph Cycle?
1. Ensures plasma and interstitial fluid communication
2. Accelerates distribution of nutrients, hormones, and dissolves gases through tissues
3. Transports insoluble lipids and tissue proteins that can’t cross capillary walls
4. Flushes chemicals to immune system tissues
What is tissue perfussion and what is it affected by?
It is: blood flow thru tissues
Affected by: blood pressure
What does Cardiovascular Regulation change?
It changes blood flow to a specific area at an appropriate time without changing blood flow to vital organs
What are the 3 Regulatory Mechanisms? And what do they do?
Autoregulation: immediate adjustments
Neural mechanisms: respond quickly to changes at specific sites
Endocrine mechanisms: control long-term changes
What do Vasodilators do?
Dilate precapillary sphincters
True or False: Local vasodilators accelerate blood flow at tissue level
True
What releases Local Vasoconstrictors? And how many capilarry beds does it affect?
released by: damaged tissues.
affects: a single capillary bed
Cardiovascular centers consists of...
And what do they do?
Consists of: cardiac and vasomotor centers of medulla oblongata
Function: adjust cardiac output and peripheral resistance
Cardioacceleratory center increases or reduces cardiac output?
Increases
What does the Cardioinhibitory center do?
reduces cardiac output
What is Vasomotor Tone produced by?
constant action of sympathetic vasoconstrictor nerves
What do baroreceptor reflexes respond to?
changes in blood pressure
What do chemoreceptor reflexes respond to?
changes in chemical composition
Baroreceptor Reflexes: When blood pressure rises, CV centers...
decrease cardiac output
Baroreceptor Reflexes: When blood pressure falls, CV centers....
increase cardiac output
Where do Baroreceptors stretch walls?
carotid sinuses: maintain blood flow to brain
aortic sinuses: monitor start of systemic circuit
right atrium:monitor end of systemic circuit
Chemoreceptors: Where is blood monitered?
carotid bodies and aortic bodies:
True or false: Chemoreceptors control bloodflow to brain
True
Explain Antidiuretic Hormone (ADH)
Released by posterior lobe of pituitary
Elevates blood pressure
Reduces water loss at kidneys
What does Angiotensin II respond to?
fall in renal blood pressure
Explain Erythropoietin (EPO)
Released at kidneys
Responds to low blood pressure
Stimulates red blood cell production
Atrial natriuretic peptide (ANP) is produced where?
cells in right atrium
Brain natriuretic peptide (BNP) is produced where?
ventricular muscle cells
What do ANP and BNP have in common?
Respond to diastolic stretching
Lower blood volume/blood pressure
Reduce stress on heart
What do blood, heard, and cardiovacular system have in common?
Work together, respond to physical changes, maintain homeostasis
What are 3 effects of light exercise?
1. extensive vasodilation occurs: increase circulation
2. venous return increases: muscle contractions
3. cardiac output rises: due to rise in venour return and atrial stretching
What are 5 effects of heavy exercise?
1. activates sympathetic nervous system
2. cardiac output increases to max.
3. restricts blood flow to nonessential organs
4. redirects blood flow to skeletal muscles, lungs, heart
5. blood supply to brain is unaffected
What are effects of regular moderate exercise?
lowers total blood cholesterol levels
What are the effects on intense exercise?
can cause severe physiological stress
What is hemorrhaging?
severe blood loss
What are responses to hemorrhaging?
cardiovascular system adjusts to maintain blood pressure and restore blood volume
What are 3 short term responses to hemorrhage?
1. to prevent drop in blood pressure
2. sympathetic nervous system triggers hypothalamus, constricts arterioles, and improves venous return
3. hormonal effecs increase cardiac output
What is shock a result of?
Failure to restore blood pressure
what are 4 long term responses to hemorrhage?
1. recall of fluids from interstitial spaces
2. aldosterone and ADH promote fluid retention and reabsorbtion
3. increase of thirst
4. red blood cells production are stimulated by EPO
Which organs have seperate mechanisms to control blood flow?
brain, heart, lungs
Where is blood flow top priority and has a high oxygen demand?
the brain
What is another term for a stroke?
cerebrovascular accident (CVA)
What is a stroke?
blockage in cerebral artery that stops blood flow
How is blood transported to the heart?
by coronary arteries
What is a heart attack?
blockage of coronary blood flow that can be fatal
What is blood flow to the lungs regulated by?
oxygen levels in alveoli
High oxygen: vessels dilate
Low oxygen: vessels constrict
Are embryonic lungs and digestive tracts funtional during fetal circulation?
No
What is the function of the placenta?
to provide respiratory functions and nutrition
Explain how blood flows thru the placenta
Blood flows thru a pair of umbilical arteries, which arise from internal iliac arteries, and enter umbilical cord
How does blood return from the placenta?
in an umbilical vein
What happens at birth?
Newborn breathes air, lungs expand, oxygen is circulated
What is foramen ovale?
interatrial opening covered by valve-like flap that directs blood from right to left atrium
What is ductus arteriosus?
short vessel that connects pulmonary and aortic trunks
How does the cardiovascular change at birth?
pulmonary vessels expand
blood flows
rising oxygen levels cause ductus arteriosus constriction
rising left atrium pressure closes foramen ovale
What are 3 age related changes in blood?
1. decreased hematocrit
2. blood clots
3. blood pooling in legs
What are 5 age related changes in the heart?
1. reduced cardiac output
2. changes in cell behavior
3. reduced elasticity of fibrous skeleton
4. progressive atherosclerosis
5. replacement of damaged cells by scar tissue
What are 3 age related changes in blood vessels?
1. arteries become less elastic
2. calcium deposits on vessel walls
3. thrombi can form