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72 Cards in this Set

  • Front
  • Back

What are the function of the heart?

generating blood pressure


routing blood


regulating blood supply

Definition: the flow of blood from the heart through the lungs back to the heart

pulmonary circulation

Definition: the flow of blood from the heart back through the body, back to the heart

systemic circulation

The heart is located _____ to the vertebral column and _____ to the sternum. It is ___ of the midline, deep to the ______ through _____ intercostal spaces. It sits on top of the ______.

anterior


posterior


left


second


fifth


diaphragm

Definition: a double-walled sac around the heart

pericardium

The pericardium is composed of a superficial ________ and a deep two-layer ________. The _______ layer lines the internal surface of the fibrous pericardium. The ______ layer lines the surface of the heart. They are separated by the ________.

fibrous pericardium


serous pericardium


parietal


visceral


pericardial cavity

The fibrous pericardium does what two things?

protects and anchors the heart


prevents overfilling of the heart with blood

The serous pericardium does what?

its allows for the heart to work in a relatively friction-free environment

What are the three layers of the heart?

epicardium, myocardium, endocardium

The epicardium is the ______ layer of the serous pericardium. It provides ______ against the friction of ___________.

visceral


protection


rubbing organs

Myocardium is the _____ layer forming the bulk of the heart. It is responsible for ______.

muscle


contraction

The endocardium is the _______ layer over a crisscrossing, interlacing layer of ____________. The inner endocardium reduces the ______ resulting from the passage of blood through the heart.

endothelial


connective tissue


friction

Definition: ridges in the ventricles

trabeculae carneae

Definition: raised areas on auricles

musculi pectinati

The _____ is the retrieving chamber of the heart. Each one has a protruding ______. The walls are marked by ______ muscles.

atrium


auricle


pectinate

What are the main veins carrying blood into the heart?

inferior vena cava


superior vena cava


coronary sinus

The ________ veins carry blood from the lungs back to the left atrium of the heart.

pulmonary

The ______ are the discharging chamber of the heart. They are marked by the __________ and the _________.

ventricles


papillary muscles


trabeculae carneae

What are the main arteries that carry blood away from the heart and where do they exit from?

pulmonary trunk - right ventricle


aorta - left ventricle

Each atrium has a flap called an ______. The ________ separates the atria from the ventricles on the exterior. The __________ separate the right and left ventricles on the exterior. The ________ separates the atria from each other. The _________ is the former location of the _________ from which blood bypassed the lungs in the fetus. The ______________ separates the ventricles.

auricle


coronary sulcus


interventricular grooces


interatrial septum


fossa ovalis


foramen ovalis


interventricular septum

The heart valves ensure _________ blood flow through the heart. The _________ valves lie between the atria and ventricles. They prevent ____ into the atria when ventricles ______.

unidirectional


atrioventricular (AV)


backflow


contract

The _________ anchor the AV valves to the _______. The _________ separates the right atrium and ventricle. The _________ separates the left atrium and ventricle.

chordae tendinae


papillary muscles


tricuspid valve


bicuspid valve

The ______ valves prevent back flow of blood into ventricles. The ___________ valve lies between the left ventricle and aorta. The ________ lies between the right ventricle and pulmonary trunk.

semilunar


aortic semilunar


pulmonary semilunar

Blood from the body flows through the right atrium into the ________ and then into the ______. Blood returns from the lungs to the _______ and enters the ________, where it is pumped back to the body.

right ventricle


lungs


left atrium


left ventricle

The ________ branch off the aorta to supply the heart. Blood returns from the heart tissues to the right atrium via the _____ and the _____.

coronary arteries


coronary sinus


cardiac veins

The fibrous skeleton of the heart consists of a plate of fibrous connective tissue. It forms fibrous rings around the _____ and _____ for support. It provides a point of attachment for the _______ and it _______________ the atria from the ventricles.

AV valves


SL valves


heart muscle


electrically insulates

Cardiac muscle cells are ______ and have a _______ located nucleus. Actin and myosin are organized to form sarcomeres, making the muscle ________. However, the ________ and ________ are not as organized as in skeletal muscle.

branched


centrally


striated


T tubules


sarcoplasmic reticulum

In cardiac muscle cells, normal contraction depends on __________. They rely on ____ respiration for ATP production. They have many ________ and are well supplied with ______. Cardiac muscle cells are also joined by _________, which allow action potentials to move from one cell to the next, thus making the cells function ________.

extracellular Ca+2


aerobic


mitochondria


blood vessels


intercalated disks


as a unit

After depolarization and partial repolarization, a ______ is reached, during which the membrane potenital only slowly repolarizes.

plateau phase

The movement of ____ through the ____channels causes depolarization. During depolarization, _____ channels close and _____ channels begin to open. Early repolarization results from closure of the ______ channels and opening of some ____ channels. The plateau exists because ___ channels remain open. The rapid phase of depolarization results from the closure of the ____ channels and the opening of many ____ channels.

sodium


sodium


potassium


calcium


sodium


potassium


calcium


calcium


potassium

Definition: phase during which cardiac muscle cells are insesnitive to further stimulation

absolute refractory period

Definition: phase during which a stronger than normal stimulation can produce an action potential

relative refractory period

Cardiac muscle has a prolonged ______ and thus a prolonged ___________, which allows time for the cardiac muscle to ______ before the next action potential causes a contraction.

depolarization


absolute refractory period


relax

Definition: a slowly developing local action potential

prepotential

Some cardiac muscle cells are _______ because of the spontaneous development of a _____. The prepotential results from the movement of ____ and _____ into the _______ cells. The ______ of the prepotential determines heart rate.

autorhythmic


prepotential


sodium


calcium


SA node


duration

The ___ node is the pacemaker of the heart. A collection of cardiac muscles is capable of spontaneously ___________.

SA


generating action potentials

The SA node and AV node are both in the ________. The AV node is connected to the __________ in the interventricular septum by the _______. The bundle branches give rise to __________, which supply the ventricles.

right atrium


bundle branches


AV bundle


Purkinje fibers

The SA node initiates action potentials, which spread across the ____ and cause them to contract. It generates impulses about __ times/min. Action potentials are ______ in the AV node, allowing the atria to contract and blood to move into the ventricles. AV node _____ the impulse approximately ________. Then the action potential passes from the atria to the ventricles via the ________.

atria


75


slowed


delays


0.11 seconds


atrioventricular bundle

An _____ records only the electrical activities of the heart. The _____ corresponds to the depolarization of the atria (SA node). The ________ corresponds to the ventricular depolarization and masks the atrial repolarization. Based on the _____ of the ECG waves and the _____ between waves, they can be used to diagnose ___________.

ECG


P wave


QRS complex


magnitude


time


heart abnormalities

During systole, that AV valve ______, the pressure inside the ventricles ________, ________ are forced to open, and blood flows into the _______ and _________.

closes


increases


semilunar valves


aorta


pulmonary trunk

At the beginning of diastole, pressure inside the ventricles _______ and ________ close to prevent back flow of blood from the aorta and pulmonary trunk to the ______.

decreases


semilunar valves


ventricles

During atrial systole, the atria ______ and complete the _________.

contract


filling of ventricles

During ventricular systole, the ventricles _____. They produce the ______ on the ECG. The AV valves ______. The contraction of ventricles causes increased _____, which forces the semilunar valve to _____. Blood is _______ the heart.

depolarize


QRS complex


close


ventricular pressure


open


ejected

Definition: the volume of blood in a ventricle just before it contracts

end-diastolic volume

Definition: the volume of blood after contraction

end-systolic volume

During ventricular diastole, the ventricles ______ and produce the _____ on the ECG. When this happens, the ventricles ____ and the blood flowing back toward the ventricles ____________. The AV valves ______. Approximately ___% of ventricular _______ occurs when blood flows from higher pressure in the ____ and ____ to the lower pressure in ventricles.

repolarize


T wave


relax


closes the semilunar valves


open


70


filling


veins


atria

Atrial repolarization produces the ____ on an ECG. The atria contract and complete ________.

P wave


ventricular filling

Contraction of the ventricles forces blood into the aorta. The maximum pressure in the aorta is the _______. _______ of the aorta maintains pressure in the aorta and produces the ________. Blood pressure in the aorta falls as _______. The minimum pressure in the aorta is the _________.

systolic pressure


Elastic recoil


dicrotic notch


blood flows out of the aorta


diastolic pressure

Hearts sounds (lub-dub) are associated with _________. The first sound occurs as the _____ and signifies the beginning of _____. The second sound occurs when ________ at the beginning of ________.

closing of heart valves


AV valves close


systole


SL valves close


ventricular diastole

Definition: average blood pressure in the aorta

mean arterial pressure

How do you find MABP?

CO (cardiac output) x PR (peripheral resistance)

Definition: amount of blood pumped by the heart per minute

cardiac output

Definition: total resistance to blood flow through blood vessels

peripheral resistance

How do you find cardiac output?

HR (heart rate) x SV (stroke volume)

Definition: the amount of blood pumped out by a ventricle with each beat

stroke volume

How do you find stroke volume?

EDV (end-diastolic volume) - ESV (end systolic volume)

Cardiac output is on average about _____. _________ is the difference between resting and maximal CO.

5 L/m


Cardiac reserve

Definition: the amount of blood returning the the heart

venous return

Increased venous return ______ stroke volume by increasing _____. Increased force of contraction ______ SV by decreasing _____.

increases


EDV


increases


ESV

Definition: modifies stroke volume through the functional characteristics of cardiac muscle cells

intrinsic regulation

Definition: the relationship between preload and the stroke volume of the heart

Starling's law of the heart

According to Starling's law, and increased preload will cause the cardiac muscle fibers to contract with _______ force and produce a _______ stroke volume.

greater


greater

Definition: the pressure against which the ventricles must pump blood

afterload

Definition: modifies heart rate and stroke volume through nervous and hormonal mechanisms

extrinsic regulation

The __________ in the medulla oblongata regulates the _______ and ________ nervous control of the heart.

cardioregulatory center


parasympathetic


sympathetic

______ and ______ are released into the blood from the adrenal medulla as a result of sympathetic stimulation. They _______ the rate and force of contraction.

epinephrine


norepinephrine


increase

Parasympathetic simulation is supplied by the ______ nerve. It ______ heart rate. Postganglionic neurons secrete ______, which increases membrane permeability to ______. Hyper polarization of the plasma membrane increases the ______________.

vagus


decreases


acetylcholine


potassium


duration of the prepotential

Sympathetic stimulation is supplied by the ______ nerves. They ____ heart rate and force of contraction. Postganglionic neurons secrete ______, which increases membrane permeability to ______. Depolarization of the plasma membrane decreases the ________.

cardiac


increase


norepinephrine


calcium


duration of the prepotential

_________ monitor blood pressure and the _______ modifies heart rate and stroke volume. In response to a decrease in blood pressure, the receptors _______ HR and SV. When blood pressure increase, the opposite happens.

baroreceptors


cardioregulatory center


increase

The _____ and _________ monitor blood oxygen levels. ________ monitor blood pH and carbon dioxide levels. These are not important for normal regulation of the heart, but are important in the regulation of respiration and blood vessel constriction.

carotid body


aortic chemoreceptor


medullary chemoreceptors

What are some age-related changed to the heart?

-decreased CO and HR


-increased cardiac arrhythmias


-hypertrophy of the left ventricle


-development of stenoses or incompetent valves


-development of coronary artery disease and heart failure

______ improves the functional capacity of the heart at all ages.

exercise