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23 Cards in this Set
- Front
- Back
introns are usually indicated by |
loops |
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there is always one more exon than an intron |
true |
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which type of RNA molecule is derived from a long single stranded RNA transcripts and known to suppress the expresssion and movement of transposons in animal germ cells? |
piRNA
they bind to Piwi proteins and degrade mRNA transcribed from transposons |
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which mechanism is used by cells to regulate gene expression and defend against certain viruses and by researchers to block expression of specific genes? |
RNA interference |
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process by which expression of a specific gene is blocked in the presence of a double-stranded RNA molecule |
RNA interference |
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Anticodon of a tRNA molecule |
It serves as the attachment site for amino acids. It is CCA. |
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which mechanism produces from a single gene, multiple mRNAs of different lengths, encoding different polypeptides? |
alternative splicing and RNA editing |
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which mechanism produces from more than one gene, multiple mRNAs of different lengths, encoding different polypeptides? |
trans-splicing |
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what is present on a bacterial gene but not a eukaryotic gene? |
shine-dalgarno sequence in the 5' UTR |
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what is the function of the shine-dalgarno sequence? |
serves as a ribosome binding site during translation |
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what critical observation led to disproving rRNA as the intermediary molecule? |
the ribosomes isolated after switching the phage-infected bacterial cells to grow in a medium containing lighter radioisotope, only contained the original heavy isoptopes. (15N and 13C). The bacterial ribosomes required for phage propagation were not newly produced upon the phage infection coupled with media switch |
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which of the following types of genes would typically only contain nucleotide sequences designed for amino acid sequence of a protein? |
neither bacterial nor eukaryotic genes. this notion does not account for sequences that are transcribed but not part of the coding region in both eukaryotic and prokaryotic genes |
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which RNA molecules help to cleave and modify eukaryotic rRNAs? |
small nucleolar RNAS (snoRNAs) |
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which mechanism allows rare bases to be incorporated into tRNA molecules? |
enzyme-mediated chemical modifications of normal RNA bases |
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function of tRNA modifying enzymes |
they convert normal RNA bases in tRNA into rare bases |
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a particular mutation occurs, which results in changing of the branchpoint A within an intron to a U. What is the most likely effect of this mutation? |
production of a longer than normal mRNA and an abnormal protein product |
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further description---> |
in the absence of a functional branchpoint, the intron will not be removed, and the coding sequence will be disrupted |
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a geneticist identifies an mRNA molecule in which the 5' end is derived from a gene on chromosome 3 and the 3' end is derived from a gene on chromosome 6. Which mechanism can explain this? |
trans-splicing |
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transcription and translation are separated temporarily as well as spatially in_______cells |
eukaryotic cells |
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which type of molecule can accomplish RNA interference by inhibiting transcription and generally is derived from sequences within the gene that it regulates? |
siRNA
these molecules are derived from their target genes and can inhibit transcription of target genes |
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this mechanism puts together exons that are derived from different genes |
trans-splicing |
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where are rRNAs modified? |
modified by snoRNAs in the nucleolus where ribosomal subunits are assembled |
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fd |
dsf |