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42 Cards in this Set

  • Front
  • Back
double helix
two strands of nucleotides twisted around each other
nucleosome
the phosphate groups in DNA create a negative charge; which attracts the DNA to the positively charged histone proteins
semiconservative replication
parental strands of DNA separate serve as templates and produce DNA molecules that have one strand of parental DNA and one strand of new DNA
Okzaki fragments
it is synthesized discontunely into small segments
DNA polymerase
catalyzes the addition of appropriate nucleotides to the new DNA strand
RNA
contains the sugar ribose
Messenger RNA
molecules are long strands of RNA are found living cells
Ribosomal RNA
is the type of RNA that associates with proteins to form ribosomes in the cytoplasm
Transfer RNA
are smaller segments of RNA nucleotides tha transport amino acids to the ribosome
transcription
the first step of the central dogma involves the synthesis of mRNA from DNA process
RNA polymerase
DNA is unzipped by the _____
Introns
these sequences are called intervening sequences
Exons
the coding sequences that remain in the final mRNA
codon
three-base code in DNA or in mRNA is called ____
translation
code is read in a process called ____
Gene regulation
ability of an organism to control which genes are transcribed in the response to the environment
Operon
is a section in the DNA that contains the genes for the proteins needed for a specific metabolic pathway
Mutation
permanent change occurs in a cell's DNA
Mutagens
substances which cause mutations
Selective Breeding
process for which desired traits are selected and passed on to their future generations
inbreeding
in which two closely related organisms are bred to have the desired traits and to eliminate the undesired ones in future generations
test cross
involves breeding an organism that has the unknown genotype with the one that is homozygous recessive for the desired trait
genetic engineering
technology that involves manipulating the DNA of one organism in order to insert exogenous DNA
genome
is the total DNA present in the nucleus of each cell
restriction enzymes
that recognize and bind to specific DNA sequences and cleave the DNA within that sequence
gel electrophoresis
an electric current is used to separate DNA fragments according to the size of the fragments
recombinant DNA
this newly generated DNA molecule; with DNA from different sources
Plasmids
small;circular double-stranded DNA molecules that occur naturally in bacteria and yeast cells
DNA ligase
joins the two DNA fragments chemically
transformation
bacterial cells take up the recombinant plasmid DNA through a process called ____
cloning
large numbers of identical bacteria each containing the inserted DNA molecules
polymerase chain reaction
makes millions of copies of a specific region
transgenic organisms
organisms genetically engineered by inserting a gene organism
DNA fingerprinting
involves separating these DNA fragments using gel electrophoresis in order to observe the distinct banding patterns
bioinformatics
creating and maintaining databases fo biological information
DNA microarrays
tiny microscope slides or silicon chips that are spotted with DNA fragments
single nucleotide polymorphisms
variations in the DNA sequence that occur when a single nucleotide in the genome is altered
haplotypes
regions of linked variations in the human genome
pharmacogenomics
study of how genetic inheritance affects the body's response to drugs
gene therapy
technique aimed at correcting mutated genes that cause human diseases
proteomics
large scale study and cataloging of the structure and function of proteins in the human body
Genomics
study of an organisms genome