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3 Cards in this Set
- Front
- Back
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What are the 3 classes of calcium channel blockers (CCBs) |
Dihydroptridone: e.g. nifedipine and amlodipine (vascular effect) - most commonly used Non-Dihydropyridine: (Phenylalkylamines) verapanil - not used much anymore Benzothiazepine: e.g. diltazen |
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What are the pharmacokinetics of Nifedipine? |
Bioavailability: 45%-55% Metabolism (first pass effect): GI and hepatic Half life (time taken for initial dose to halve in bloodstream: 2 hours |
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Side effects of vasodilators |
Hypotension Headaches Flushing Palpitations Bradycardia Oedema Constipation |
