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6 Cards in this Set
- Front
- Back
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Name 6 theories for etiology of rosacea?
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1 - innate immune system (incr cathelicidins, kalikrin)
2 - UVR (stimulates angiogenesis, VEGF, icnr ROS, incr MMP) 3 - Change in vasculature: incr BF, flush, incr EGF 4 - Decr epidermal barrier fn (hence sensitive, incr water loss) 5 - Neurologic inflam: VD due to neuron release 6 - Microbes: demodex mites incr staph |
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Name 4 forms of rosacea...and how best to tx them
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1 - Erythrotelangectias (flush, erythema, telangecasia)
-tx: avoid triggers, SPF, gentle skin care 2 - Papulopustular -tx: topical or po Abx x4-6wks (va acne 4-6 months) 3. Ocular -tx: optho consult if eye pain, photophobia lavage of eyelid margins 4. Phymatous changes(hypertrophy of sebaceous glands in nasal area) -5 types: Ganthophma (chin) Mentophyma (forehead) Blepharphyma (eyelid) Otophyma (ear lobes) Rhinophyma (nose) -tx: po isotretinoin surgery CO2 laser |
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What is PERT syndrome?
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Post erythema revealed telangectaia
-need to warn patient about -a/f tx po Abx, need to keep on topcial or else relapse within 3-6months |
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What are some other variants of rosacea?
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Granulomatous rosacea
Rosacea fulminans Rosacea conglobata Extra facial lesions of rosacea Pre-rosacea: freq face flushing Lupus miliaris dissem faceai |
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What are the 3 OCP FDA approved for acne?
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Ortho tri-cyclen
Estrostep Yaz |
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What are 2 mech of action for spironolactone?
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-inhiits 5 alpha reductase
-androgen receptor blocker |
