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26 Cards in this Set
- Front
- Back
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Insulin order of fast acting
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– lispro (humilog)
– aspart (novolog) – regular – NPH (lente) – Ultralente – Lantus |
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What are the shorter acting sulfonurea type drugs
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– Meglitinides
– end in glinide |
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Metformin action and contraindicationa
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– inhibits hepatic gluconeogenesis and increases peripheral sensitivity
– don’t give to elderly or renal disease |
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Thiazolidinediones SE’s
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– glitazones
– weight gain, edema, liver damage |
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Myxedema coma Tx
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– IV levothyroxine and IV hydrocortisone (until you rule out Addisons)
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The names for MEN syndromes
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– Wermers is 1 and Sipple’s is 2
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Markers of increased bone turnover
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– Urinary N-telopeptides
– deoxypyridinoline |
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Paget’s disease (bone)
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– normal Ca and P
– do radionuclide bone scan – give bisphos and calcitonin |
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Hyperparathyroidism Tx
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– give IV fluids, bisphos and calcitonin – lasix if renal or heart failure
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Acromegaly medical treatment
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– octreotide
– pergolide – pegvisomant |
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Prolactinoma medical treatment
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– Cabergoline
– Bromocriptine – Pergolide |
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Adrenal insufficiency Dx
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– hyperkalemia only in 1o (b/c 2o is due to decreased ACTH and not actual adrenal glad dysfunction, so mineralcorticoids still work)
– random > 20 excludes – stress test < 20 confirms |
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Conn syndrome Dx
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– presents w/ muscles weakness and numbness
– metabolic alkalosis – hypomagnesemia – increased 24 hr urine ALD – can tx w/ spironololactone if hyperplasia |
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What are most thyroid nodules?
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– benign colloid nodules
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Bartters syndrome
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– defective LOH resorption of Na and Cl leads to RAAS activation
– Renin and ALD are both increased w/ normal BP – you loose K and H – can be associated w/ MR if presents early |
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What labs make you check thyroid function?
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– hyponatremia
– hyperlipidemia – increased CK |
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How do sarcoid and heme malignancies cause hypercalcemia?
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– they increase 1,25-D conversion
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Nephrogenic DI Tx
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– Indomethacin and HCTZ
– if from Li tox, do Amiloride |
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21-OH deficiency
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– can present later w/out salt wasting (non-classic)=
– 17-a-something builds up |
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17-OH deficiency
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– delayed puberty and increased mineralocorticoids
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11-OH deficiency
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– increased androgens and increased mineralocorticoids
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3-B-OH deficiency
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– DHEA-S excess w/ decreased testosterone and decreased mineralocorticoids
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Sick euthyroid syndrome labs
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– decreased T3 but normal T4 and TSH
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Low RAIU w/ thyrotoxicity
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– thyroiditis
– OD – struma ovarii – iodine induced |
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Milk alkali Triad
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– hypercalcemia
– metabolic alkalosis – renal insufficiency |
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Untreated hypothyroid
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– increase clast so rapid bone loss
– also increased risk of thyroid lymphoma regardless |
