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23 Cards in this Set
- Front
- Back
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Most common cerebral tumor in AIDS
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B-cell lymphoma
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Cushing's triad in brain tumor
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↑ICP leads to bradycardia with hypertension, Cheyne-Stokes breathing,
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The most common primary cerebral neoplasm, peaks in middle age, CT shows central necrosis of mass surrounded by a bright ring
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glioblastoma multiform
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Common tumor in cerebral hemispherees, grows slow and associated with calcifications on Xray, histology shows large round nuclei with clear halo of cytoplasm ("fried egg")
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Oligodendroglioma
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Diseases that have + psammoma bodies:
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meningioma
serous papillary cystadenocarcinoma (ovarian) papillary adenocarcinoma of thyroid mesotheiloma "PSMM" |
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What are the genetic components of neuroblastoma and retinoblastoma, respectively.
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N-myc amplification
rb deletion |
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von Hippel-Lindau can ectopiclly produce________leading to________.
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erythropoietin; erythrocytosis
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This drug is used to tx HTN ADR are hypokalemia, hypercalcemia, and hyperuricemia CI in sulfa-allergic patients. MOA
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block Na+ uptake in the DCT
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Diltiazam, nifedipine, and verapamil affect smooth mm to decrease HTN. Where do each have their greatest effect?
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Diltiazem - vasculature and heart EQUALLY
Nifedipine - vasculature Verapamil - HEART (Verapamil = Ventricle) |
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What is the odd ADR of minoxidil?
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hypertrichosis
growth of body hair (this is Rogaine) also used to tx HTN via vasodilation |
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So you are hellbent on loosing your medical license because during a hypertensive emergency (210/150) you gave the pt nitroprusside p.o.. How did he die and what will you do now?
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nitroprusside orally is metabolized to cyanide which blocks oxidative phosphorylation in mitochondria, no ATP, no living.
You will most likely suck dick for coke |
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Target blood pressures in the various patients:
All patients High risk CAD Stable angina Unstable angina MI CHF |
140/90
130/80 130/80 130/80 130/80 120/80 |
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What is stage II HTN
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160/100
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Protocol for treating a hypertensive emergency
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Drop that diastolic to 130 if patient has a pre-existing condition (CHF, cerebral hemorrhage)
IV nitroprusside |
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Receptors:
M N |
Bind ACh, G protein coupled, found extensively in the brain
Bind ACh, are ligand-gated ion channels, ionotropic, modifies the states of neurons |
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Asian dude presents with hx of blindness and paraplegia, make the dx
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Devic's syndrome
varient of MS |
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Child presents with visual, motor, auditory and psychiatric disorders. CT of the head shows diffuse sclerosis of the occipital lobes and corpus callosum. Adrenals are atrophied
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Schilder's diffuse cerebral sclerosis
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Kid shows up with mom after post-vaccination with hyperacute allergic reaction with brain sxs of edema, petechiae, bleeding.
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Hemorrhagic encephalomyelitis
usually from measles or smallpox |
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pt presents post infection with muscle weakness and paralysis that began in the lower extremities and has ascended. He has diminished reflexes and is currently in respiratory failure. Make the dx and describe the CSF
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This is Guillian-Barre syndrome
infection could be viral or from camplytomacter CSF shows an increase in protein without an increase in cells (albumin-cytologic dissociation) |
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pt presents acutely with sxs of quadraparesis, dysphagia, and diplopia, and fluctuating consciousness. T2 MRI shows bilateral symmetrical hyperintensities in the caudate nucleus and putamen, sparing the globus pallidus. What caused this?
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Rapid correction of hyponatremia (locked in syndrome)
also seen in liver transplant pts |
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What are the trinucleotide repeats in the following:
Huntington's Friedreich's ataxia Spinocerebellar degeneration |
CAG
GAA CAG |
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What stain do you use to stain Pick bodies?
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Silver stain
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Three great ways to induce Parkinsonian like sxs?
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Manganese intoxication
synthetic heroin phenothiazine - insecticide and contained in the synthetic dye "methylene blue" |
