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236 Cards in this Set

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Positive Giemsa Stain
Borrelia, Plasmodium, trypanosomes, Chlamydia
#microbiology
Ziehl Neelsen Stain
Acid Fast orgnaism
#microbiology
Silver Stain
Fungal (PCP), Legionella
#microbiology
Obligate Aerobes
Norcardia
Pseudomonas
Mtb
Bacillus


Mn: These Nagging Pests Must Breath
#microbiology
Obligate Anae3robes
Clostridium
Bacteroides
Actinomyces

Mn: These Can't Breathe Air

AminOglycosides ineffective because they require O2 to fnx
#microbiology
Intracelular Bugs
Obligate:
Rickettsia, Chlamydia (cannot make own ATP)

Facultative: Salmonella, Neisseria, Brucella, Mycobacterium, Listeria, Francisella, Legionella, Yersinia

Mn: Some Nasty Bugs May Live FacultativeLY
#microbiology
Catalase Positive Organisms
S aureus
Serratia
Pseudomonas
Actinomyces
Candida
E coli

Mn: make Some SPACE for your cats

people with granulomatous ds (NADPH oxidase deficiency) will have recurrent infx because they can survive the limited H2O2 prodxn
#microbiology
Bacteria with toxins induced by viral Lysogeny
ShigA-like Toxin
Botuliism Toxin
Chlorera Toxin
Diphtheria toxin
Erythrogenic Toxcin of S Pyogenes

Mn: ABCDE
#microbiology
pupil constricts to accomodation but not light
Argyll-Robertson pupil
(aka "Prostitutes Pupil"

3* syphillis
#microbiology
Argyll-Robertson Pupil
aka "Prostitutes Pupil"

constricts to accomodation but does not react to light

3* syphillis
#microbiology
Weil Felix reaction
anti-Rickettsial cross react with Proteus antigens

(Q fever is negative)
#microbiology
Rashes which involve the palms and soles
Coxsackie A
Rocky Mountain Spotted Fever (R rickettskii, Dermacentor)
Syphillis

Mn: you Drive CARS with your palms and soles
#microbiology
Chalmydia trachomatis serotypes
A-C: Chronic infxs which cause blindness in Africa

Mn: ABC: Africa, Blindness, Chronic Infx

D-K: everything else

L1-2 : Lymphogranuloma venereum
#microbiology
Nematode Routes of Infx
Ingested:
Enterobius, Ascaris, Trichinella (Mn: EAT)

Cutaneous: Strongyloides, Ancylostoma, Necator (Mn: SANd)
#microbiology
Parasite which causes
Brain cysts & seizures
Taenia solium (Cysticercosis)

Cestode (tapeworm)

Eat the larva → intestinal tapeworms

Eath the eggs → neurocysticercocsis "swiss cheese brain"

DOC: Praziquantel
#microbiology #parasites
Parasite which causes
Liver Cysts
Echinococcus granulosus

Cestode (tapeworm)

Eating eggs from dog feces → liver cysts

if cyst disturbed (ie surgical removal) → release of antigens → anaphylaxis

surgeons inject ethanol to fix ts before removing

DOC: mebendazole
#microbiology #parasites
Parasite which causes
B12 Deficiency
Diphyllobothrium latum

Cestode (tapeworm)

Raw Freshwater Fish
#microbiology #parasites
Parasite which causes
Cholangiocarcinoma
Clonorchis sinensis

Trematode (Fluke)

undercooked fish → biliary tract inflam → brown gallstones → cholangiocarcinoma

DOC: Praqiqunatel (all trematodes)
#microbiology #parasites
Parasite which causes
Hemoptysis
Paragonimus westermani

Trematode (Fluke)

Undercooked Crab meat

inflam & bacterial 2° infx of lung

DOC: Praqiqunatel (all trematodes)
#microbiology #parasites
Parasite which causes
Portal hypertension
Schistosoma mansoni

Trematode (Fluke)

Penetrate skin → inflam, granulomas, fibrosis

DOC: Praqiqunatel (all trematodes)
#microbiology #parasites
Parasite which causes
bladder cancer
Schistosoma haematobium

Trematode (Fluke)

Penetrate skin → inflam, granulomas, fibrosis

S haematobium: irritates bladder → hematuria → bladder cancer

DOC: Praqiqunatel (all trematodes)
#microbiology #parasites
Parasite which causes
Microcytic Anemia
Hookworms: Ancylostoma & Necator (ANemia)

Penetrate feet → suck blood from intestinal walls

DOC: mebendazole

Mn: Worms are Bendy, treat with Bendazoles
#microbiology #parasites
Parasite which causes
Perianal pruritis
Enterobius (Pinworm)

Ingest food
Scotch Tape Test
#microbiology #parasites
Flashcard note: Worms not carded
Ascaris Lumbricoides, Trich spiralis, Stronyloides stercoralis, Dracunculus medinensins, oncheocerca volvus, loa loa, wucheria banchronfi, toxcara canis
#microbiology #parasites
HIV pt with superficial vascular proliferation
If biopsy reveals lymphocytic inflammation: Kapsoi's sarcoma (HHV8)

if biopsy primarily PMN infiltrate: Bacillary angiomatosis of bartonella hensellae
#microbiology #HIV
HIV pt with Encephaolopathy
reactivation of latent JC virus (PML)

results in demyelination
#microbiology #HIV
HIV pt with ring enhancing lesions in brain
Brain abscesses of Toxoplasma gondii
#microbiology #HIV
HIV pt with dementia
directly caused by HIV
#microbiology #HIV
Cause of HIV Hairy leukoplakia
EBV
#microbiology #HIV
Cause of HIV pneumonia
Typical: PCP
Interstitial: CMV
TB-like: Mai
#microbiology #HIV
Bug which mimics Appendicitis
Yersinia Entercolitica

mesenteric adenitis
#microbiology #HIV
Viruses which cause watery diarrhea
rotavirus, adenovirus norwalk virus

NB: no virus causes bloody diarrhea
#microbiology #HIV
Neonate with:
chorioretinitis,
hydrocephalus,
intracranial calcifications
Toxoplasma gondii
#microbiology #neonates
Neonate with:
PDA, cataraqcts and deafness
Rubella
#microbiology #neonates
Neonate with:
hearing loss, seizures, petechial "blueberry muffin" rash
CMV
#microbiology #neonates
Neonate with:
recurrent infx, chronic diarrhea
HIV
#microbiology #neonates
Neonate with:
temproal encephalitis, vesicular lesions
HSV-2
#microbiology #neonates
Neonate with:
saddle nose, CN deafness
sphyillis

notched teeth, short maxilla and saber shins as well
#microbiology #neonates
Several days of fever followed by macular rash
Roseola of HHV-6

esp neonates
#microbiology
#neonates
Rash with post-auricular lymphadenopathy
Rubella (German Measles)
#microbiology
Nosocomal Infx in Newborn nursery
CMV, RSV
#microbiology
#neonates
Nosocomial Infx 2° to Urinary catheteriation
E coli, Proteus
#microbiology
Nosocomial Infx 2° Repsiratory Thepray
Pseudomonas

Legionella if water aerosols
#microbiology
Nosocomical Infx 2° Dialysis
HBV
#microbiology
Bilateral Bell's Palsy
Borrelia Burgdorferi
#microbiology #neurology
Aztreonam spectrum
Gram negative aerobes!

Syngergistic with aminoglycosides

Best for penicillin allergic pts with bad kidneys who cannot tolerate high dose aminoglycosides
#pharmacology #toxicities
ANtibiotics to avoid in pregnancy
Clarithormycin - embryotoxic
Sulfonamides - kernicterus
Aminoglycosides -ototoxic
Fluoroquinolones - cartilage
Metronidazole - mutagenic
tetracyclines - bone
Ribavirn - tertagoen
grisoefulvin 0teratogen
chloramphenicol -grey baby

Mn: Countless SAFe Moms Take Really Good Care
#pregnancy #pathology #pharmacology #toxicity
HIV integrase inhibitors
Raltegravir

Inhibits HIV integrase

causes hypercholesteorlemia
#HIV #pharmacology
Raltegravir
unique: integrase Inhibitor v HIV

causes hypercholesteorlemia
#HIV #pharmacology
NNRTI's
NeVIRapine
EfaVIRenz
DelaVIRdine

do not req phosphoyrlation to beocme active
do not compete v nucleotides
#HIV #pharmacology
IFN's
IFN αand βinhibit viral protein synth
IFN γincreases MHC expressn
all activate NKs

IFNα: chornic Hep B anc C, Kapsoi's sarcoma
IFN β: MS
IFN γ: NADPHoxidase deficiency

Toxicity: PMNpenia
#immunology #pharmacology
VJ recomination vs VDJ recombination
VJ: light chains
VDJ: heavy chains
#immunology
Mn: IL's
Hot T-Bone stEAk

IL1: Fever
2: T cells
3: Bone Marrow
4: IgE prodxn
5: IgA prodxn

"Clean up on Aisle 8" PMN's recruited by Il8
#immunology
CD14
CD14 and CD40 = M∅

CD14 is receptor for endotoxin
#immunology
CD40
CD14 and CD40 = M∅

CD14 is receptor for endotoxin
#immunology
Tamoxifen v Raloxifene
Tamoxifen:
Agonist in Bone & Endometrium
Antagonist in Breast

Raloxifene:
Agonst on Bone
Antagonist in Breat & Endometrium

Mn: "Tammy still got Cancer"
#pharmacology #neoplasia
Daclizumab
anti-IL2 antibody

used to prevent acute rjxn of renal transplant
#pharmacology #immunology
Ataxia Telangiectasia
ATM gene for DNA repair

Cerebellar Defects (Ataxia)
Spider angiomas (telangiectasia)
IgA deficiency
#pathology #immunology #geneticdzs
Wickott-Aldrich Sro
X linked
progressive deltion of Bs and T's

Triad of TIE
Thromobcytopenic Purpura
Infx
Eczema

severely ↓ IgM
↑ IgE & IgA
#pathology #immunology #geneticdzs
Mets to the brain are likely from
Lung > Breast > Kidney > Melanoma

will present at grey/white jnx
#pathology #neoplasia
Mets to the liver are likely from
Colon > stomach >pancreas
#pathology #neoplasia
Mets to the bone are likely form
Prostate, breast > lung >thyroid, testes
#pathology #neoplasia
Maintenance Dose
Target Concentration * Clearance

adjusted for bioavilability

CL = Vd * Ke = 0.7*Vd/λ
#pharmacology
calculating λ
λ = 0.7 * Vd/ CL

λ = Vd * Ke

Ke = 0.7/λ
#pharmacology
Bethanechol
Direct Muscarinic Agonist

most fnx on GI & GU

Uses: Ileus & urinary retention

Mn: Bethany's Bowels & Bladder Call

Direct agonists:
Bethanechol, Carbachol, Pilocarpine, Methacholine
#pharmacology #autonomics
Carbachol
Direct muscarinic agonist

Used for glaucoma

Mn: "CARBon copy of ACh"

Direct agonists:
Bethanechol, Carbachol, Pilocarpine, Methacholine
#pharmacology #autonomics
Pilocarpine
Direct Muscarinic agonist

Potent activator of sweat, tears, and saliva

Mn: This PILLOw has been cried, sweat, and drooled upon

Direct agonists:
Bethanechol, Carbachol, Pilocarpine, Methacholine
#pharmacology #autonomics
Methacholine
Direct Muscarinic Agonist

Used for challenge diagnosis of Asthma

Direct agonists:
Bethanechol, Carbachol, Pilocarpine, Methacholine
#pharmacology #autonomics
Neostigmine
anitcholinesterase

Post-op reversal of NMJ blockade

NeOstigmine = NO CNS penetration
#pharmacology #autonomics
Pyridostigmine
anticholinesterase

long acting, used for myasthenia gravis

Mn: PyRIDostigmine gets RID of MG
#pharmacology #autonomics
Physostigmine
anticholinesterase used for glaucoma

✓xBBB → used v Atropine OD

PHYsostigmine PHYxes atropine OD
#pharmacology #autonomics
Echothiophate
anticholinesterase used vs Glaucoma
#pharmacology #autonomics
Donepazil
anitcholinesterase used v Alzheimer's
#pharmacology #autonomics
Benztropine
muscarinic antagonist used in parkinson's

Mn: PARKing my BENZ
#pharmacology #ans
DOC: Htn + Renal Dz
Clonidine or α-methyldopa

centrally acting α2 agonists

↓ SNS outflow
no ↓ bloodflow to kidneys
#pharmacology #ans
α2 antagonists
mirtazapine

treatment for depression

causes sedation, hypercholestrerlemia and ↑ appetite
#pharmacology #ans
Mirtazapine
α2 antagonist used v depression

causes sedation, hypercholestrerlemia and ↑ appetite
#pharmacology #ans
β1 selective antagonists
acebutolol
betaxolol (partial)
esmolol
atenolol
metoprolol

Mn: A BEAM of β1 blockers
#pharmacology #ans
Non-selective β antagonists
Propraolol, Timolol, Nadolol, Pindolol

Mn: Please Try Not βeing Picky
#pharmacology #ans
Nonselective α + β antagonits
carvedilol, labetalol
#pharmacology #ans
partial β agonists
Pindolol Acebutolol

Mn: Partial Agonists
#pharmacology #ans
DOC: Theophylline OD
β blockers
#pharmacology #toxicity
Drug which causes

Coronary vasospasm
cocaine
supatriptan
#pharmacology #toxicity
Drug which causes
cutaneous flusshing
VANC

Vancomycin
Adenosine
Niacin
Ca2+ channel blockers
#pharmacology #toxicity
Drug which causes
TDP
Class III (K blockers: sotalol and antiarrhytmics and Class IA (DQP)

Class III: Ibutilide, Sotalol, Bretylium, Amiodarone, Dofetilide

Mn: K IS BAD (Amiodarone ≠ TDP)
#pharmacology #toxicity
Drug which causes
Agranulocytosis
Cloazpine
Carbamazepine
Colchicine
Colchicine
Propthiouracil
Methimazole
Dapsone

Mj: Agranulocyctosis Could Certainly Cause Pretty Major Damage)
#pharmacology #toxicity
Drug which causes
Direct Coombs + Hemolytic Anemia
Methyldopa
#pharmacology #toxicity
Drug which causes
Hemolysis in G6PD deficiencts
Mn: Hemolysis IS PAINful

INH
Sulfas
Primaquin
Aspirin
Ibuprofen
Nitrofurantoin
#pharmacology #toxicity
Drug which causes
Megaoloblastic Anemia
Phenytoin
Methortrexate
Sulfas

Mn: having a blast with PMS
#pharmacology #toxicity
Drug which causes
Pulmonary Fibrosis
Bleomycin
Amiodarone
Busulfan

Mn: hard to BLAB on with Pulmonary Fibrosis
#pharmacology #toxicity
Drug which causes
Cholestatic Hepatitis
Macrolides
#pharmacology #toxicity
Drug which causes
Hepatic Necrosis
Mn: wreaking HAVAc on the liver

Halothane
Acetaminophen
Valproic Acid
Amanita phalloides
#pharmacology #toxicity
Drugs which cause pseudomembranous colitis
clindamycin, ampicillin
#pharmacology #toxicity
Drug which causes
gynecomastia
Mj: Some Drugs Create Awesome Knockers

Spirolactone, Digitalis, Cimetidine, Alcohol, Ketoconazole, Estrogens
#pharmacology #toxicity
Drug which causes
Hot Flashes
Tamoxifen, Clomiphene
#pharmacology #toxicity
Drug which causes
Hypothyroidism
Lithium, Amiodarone, Sulfas
#pharmacology #toxicity
Drug which causes
Hyperglycemia
Niacin, Tacrolimus, Protease Inhibitors
#pharmacology #toxicity
Drug which causes
Disulfram Like Reaction
Metronidazole
Cephalosporins
Procarbazine
1st gen sulfonyruas
#pharmacology #toxicity
Drug which causes
Sizures
Wellburtin (Buproprion)
Imipenem, Cilastatin
INH
#pharmacology #toxicity
Drug which causes
Gout
Furosemide, Thiazides, Niacin, Cyclosproine, Pyrazinamide
#pharmacology #toxicity
Drug which causes
Myopathies
Fibrates, Niacin, Colchicine, Hydroxychlorquine, IFNα, Penicillamine, Statins, Glucocorticoids

Fish N CHIPS Give you Myopathies
#pharmacology #toxicity
Drug which causes
Osteoporosis
Corticosteroids, Heparin
#pharmacology #toxicity
Drug which causes
Stevens-Johnson Rash
Mn: Bad Rash after PEC SLAPP

Penicillin, Ethosuximide, Carbamazepine, Sulfas, Lamotrigine, Allopurinol, PHenytoin, Phenobarbitol
#pharmacology #toxicity
Drug which causes
SLE
Hydralazine, INH, Procainamide, Phenytoin

Mn: It's not HIPP to have Lupus
#pharmacology #toxicity
Drug which causes
Interstitial Nephritis
Methicillin
NSAIDS
Furosemide
#pharmacology #toxicity
Drug which causes
Hemorrhagic Cystitis
Cyclophosphamide, Isofosphamine (prevent w/ mesna coadmin)
#pharmacology #toxicity
Drug which causes
SIADH
Carbamazepine,Cyclophosphamide
#pharmacology #toxicity
Sulfa Drugs
Mn: Pop FACTSSS

Probenecid
Furosemide
Acetazolamide
Celecoxib
Thiazides
Sulfonamide antibiotics
Sulfasalazine
Sulfonylureas
#pharmacology #toxicity
erythroderma, lymphadenopathy, hepatosplenomegaly, atypical T cells
Sezary Sro aka Mycois Fungoides

Indolent CD4 lymphoma

adult onset, cutaneous patches

Contrast to "Adult T cell lymphoma" HTLV-1 induced aggressive neoplasm
#pathology #neoplasia
HTLV-1
induces Adult T cell lymphoma

aggressive, presents with cutaneous lesions
#pathology #neoplasia
Back Pain, Fever, Night Sweats, Weight Loss
Pott's Dz

NB: Fever, Night Sweats & Weight Loss = Classic B Cell Lymphoma signs
#buzzwords
McCune Albright Sro

fundamental defect
mosaic G protein signalling mutation
#buzzwords
horizontal diplopia
Intranuclear opthalmoplegia 2° to damage to MLF
#buzzwords
Dog or cat bit → Infx at bite
pasteurella multilocida
#buzzwords
Which collagen defective in ehler's danlos
Type 3
#pathology #geneticdzs
Hepatosplenomegaly, Osteoporosis, Neurologic Sx
Gaucher's Dz
#buzzwords
Hamartomous GI polyps, Hyperpigmentation of Mouth, ands and feet
Peutz-Jeghers, genetic benign polyposis

likely to cause bowl obstrx, ↑ CA risk
#buzzwords
Hereditary nephritis, sensorineural hearing loss, cartaracts
alp[ort's mutation in α chain of Type 4 collagen
#buzzwords
Extremely Hungry, Extremely Sexual, Hyperoral, Extremely Docile
Kluver-Bucy Sro: Bilateral Amydgala Lesions
#buzzwords
Sequelae of Plummer Vincent Sro
Esophageal Squamous Cell Carcinoma
#pathology #neoplasia #gastrointestinal
Bilateral Amydgala Lesions
Kluver-Bucy Sro: Hyperphagic, Hypersexual, Hyperoral, Extremely Docile
#pathology #neurology
Hypotension, Hypokalemic, Metabolic Alkalosis
Conn Sro
#buzzwords
Indurated, ulcerated gential lesion
Non-painful: Syphillic Chancre

Painful: Haemophilus ducreyi chancroid
#buzzwords
Infant with failure to thrive, hepatosplenomegaly, neurodegeneration
Neiman Pick
#buzzwords
Infant with hypoglycemia, failure to thrive, hepatomegaly
Cori's Dz (debranching enzyme)
#buzzwords
Infant with microcephaly, rocker0bottom feet, clenched hands, structural heart defect
Edward's Sro
#buzzwords
Mucosal bleeding and prolonged bleeding time
Glanzmann's Thrombasthenia

(lack of GpIIb/IIIa)
#buzzwords
Multiple Colonic Polyps, Osteomas, Soft Ts Tumors, Impacted supernumiary teeth
Gardner's Sro,

subtype of FAP
#buzzwords
Painful blue fingers, toes + hemolytic anemia
Myobplasma pneumonia induced cold agglutinin dz
#buzzwords
Osler's Nodules vs Janeway lesions
Osler's are painful
#buzzwords
Adult onset painless jaundice
pancreatic cancer obstructing bile duct
#buzzwords
Palpable purpura on buttocks &legs, joint pain abdominal pain (child)
Henloch-Schonlein IgA vasculitis
#buzzwords
Polyuria, acidosis, growth failure, elyte imbalances
Fanconi's Sro
#buzzwords
bilateral renal cell carcinomas, hemangioblastomas, pheos
VHL deletion 3
#buzzwords
Retinal Hemorrhages with pale centers
Roth spots: Bacterial Endocarditis
#buzzwords
Fanconi's Anemia
Short Stature
Aplastic Anemia
often progresses to AML
#buzzwords
Strawberry Tongue
Scarlet Fever
Kawasaki
Toxic Shock
#buzzwords
Thyroid, Parathyroid Tumors + Pheos
MEN2A ret tumor suppressor
#buzzwords
Thyroid Tumors, Pheos, Ganglioneurotamtosis
MEN2B
ret tumor suppressor
#buzzwords
anti-centromere antibodies
CREST
#buzzwords
pANCA v cANCA
pANCA = microscopic polyangitis, Churg Strauss
cANCA = Wegners
#buzzwords
anti-topoisomerase antibodies
diffuse scleroderma
#buzzwords
Basophilic stains w/in RBCs
Nuclear Remnants: Howell-Jolly Bodies --nonfnx/absent spleen

Stippling: Lead poisoning or Sideroblastic Anemia
#buzzwords
Boot Shaped Heart on CXR
Tetrology of Fallot

or

RVH
#buzzwords
Brown tumor of bone
hemorrhage due to

1. hyperparathyroidism
2. osteitis fibrosa cystica
#buzzwords
Cardiomegaly with apical atrophy
Chagas Dz
#buzzwords
Chocolate Cyst in Ovary
Endometriosis
#buzzwords
Circular grouping of dark tumor cells surrounding neurofibrils
Hormer Wright rosettes

neuroblastoma,medulloblastoma, retinoblastoma
#buzzwords
Degeneration of the dorsal column nerves
3* syphilis
#buzzwords
desquamated epithelium casts in sputum
curshmann's spirals of bronchial asthma
#buzzwords
disarayed granulosa cells in eosinophilic fluid
Call-Exner bodies (granulosa theca cell tumor of the ovary)
#buzzwords
curshmann's spirals
desquamated epithelium casts in sputum

indicative of bronchial asthma
#buzzwords
Call-Exner bodies
disarayed granulosa cells in eosinophilic fluid

indicative of granulosa theca cell tumor of the ovary
#buzzwords
"Orphan Annie" cells
enlarged thyroid cells with ground glass nuclei

indicative of papillary carcinoma of the thyroid
#buzzwords
enlarged thyroid cells with ground glass nuclei
"Orphan Annie" cells

indicative of papillary carcinoma of the thyroid
#buzzwords
eosinophilic cytoplasmic inclusion in liver cell
mallory bodies of alcoholic liver dz
#buzzwords
mallory bodies on liver biopsy
eosinophilic inclusions in cytoplasm indicative of alcoholic liver dz
#buzzwords
Lewy Body
eosinophilic inclusion in nerve cytoplasm

Parkinson's dz
#buzzwords
eosinophilic inclusion in nerve cytoplasm
Lewy Body

Parkinson's dz
#buzzwords
Eosinophilic inclusion in cytoplasm of hippocampal nerve cells
rabies virus
#buzzwords
glomerulus-like strx surrounding vessel in germ cells
Schiller Duval bodies

(yolk sac tumor)
#buzzwords
Schiller Duval bodies
yolk sac tumor

glomerulus-like strx surrounding vessel in germ cells
#buzzwords
"Hair on End" (crew cut) appearance on x ray
marrow expansion of β thal or sickler
#buzzwords
Honey Comb Lung on X ray
interstitial fibrosis
#buzzwords
Iron containing nodules in alveolar septum
ferruginous bodies

indicative of asbestosis w/ ↑ mesothelioma
#buzzwords
Colon appears as lead pipe on x ray
UC: loss of haustra
#buzzwords
Lytic "hole-punched" bone lesions on X-ray
Multiple Myeloma
#buzzwords
Blue Domed Cyst on Breast
Fibrocystic Change
#buzzwords
Nutmeg Liver
RHF
#buzzwords
Onion Skin periosteal reaction
Ewin'g ssarcoma (Malignant round cell tumor)
#buzzwords
Codman's triangle
Osteosarcoma
Ewing's sarcoma
Pyogenic osteomyelitis
#buzzwords
Podocyte fusion on EM
Minimal change dz
#buzzwords
protein aggregates in neurons from hyperphosphorylation of tau protein
neurofibrillary tangels of Azhemiers and CJD
#buzzwords
Rectangular, crystal like inclusions in Leydig cells
Reinke crystals

indicative of
leydig cell tumor
#buzzwords
Reinke crystals
Rectangular, crystal like inclusions in Leydig cells

indicative of
leydig cell tumor
#buzzwords
silver-staining spherical aggregation of tau proteins in neurons
pick bodies

pick's dementia: progressive personality changes
#buzzwords
pick bodies
silver-staining spherical aggregation of tau proteins in neurons

pick's dementia: progressive personality changes
#buzzwords
"Soap Bubble" mass in femur
giant cell tumor of bone (benign)
#buzzwords
Spikes on basement membrane, "dome like" subepithelial deposits
Membranous glomerulonephritis
(may progress to nephrotic)
#buzzwords
stacks of RBC's in blood
rouleaux formation
multiple myeloma
#buzzwords
thrombi w/ coloration stripes
Zahn lines of arterial thrombus:

alternating layers of platelets & rbcs
#buzzwords
thyroid like apperance of kidney
chronic bacterial pyelonephritis
#buzzwords
Tram Tack LM
membranoproliferative glomerulonephritic
#buzzwords
Smudged WBC's
CLL (B cells)
#buzzwords
"wire loop" glomerular LM
Lupus nephropathy
#buzzwords
yellow CSF
xanthochroma of previous SAH
#buzzwords
DOC: arrhytmia w/in damaged cardiac ts
Class IB anti-arrhythmics
#buzzwords
DOC: breast cancer in post menopausal women
aromatase inhibitors

anastrazole, letrozole, exemestane
#buzzwords
DOC: chlamydia trachomatis
Doxy
add ceftriaxone for gonorrhea coinfx

erythromycin eyedrops for neonate
#buzzwords
DOC: chronic gout
probenecid (underexcretor)
allopurinol (overproducer)
#buzzwords
DOC: CML
Imatinib
#buzzwords
DOC: clostridii
botulinum: antitoxin
difficil: oral metronidazole
tetani: antitoxin + vaccine booster + diazepam
#buzzwords
DOC: Cyrptococcus neoformans
Fluconazole
#buzzwords
DOC: Cystic Fibrosis
N-acetylcysteine + antipseudomonal prophylaxis (trobramycin + azithromycin)
#buzzwords
DOC: diabetes insipidus
Central:
Desmospressin

Nephrogenic:
Hydrochlorothiazide
Indomethacin
Amiloride
#buzzwords
DOC: DKA
Fluids, insulin, K+
`#buzzwords
DOC: enterococci
Vanc/amp + amioglycoside
#buzzwords
DOC: Haemophilus influenzae
rifampin
#buzzwords
DOC: hemorrhagic cystitis
mesna
#buzzwords
DOC: Legionella
Erythromycin
#buzzwords
DOC: malaria
Blood: chlorquine/mefloquin

liver: primaquine
#buzzwords
DOC: Multiple Sclerosis
β IFN
#buzzwords
DOC: prostate cancer
leuprolide / continuous GnRH infusion

flutamide
#buzzwords
DOC: uterine fibroids
leuprolide / continuous GnRH infusion
#buzzwords
DOC: pulmonary hypertension
bosentan
#buzzwords
DOC: Rickettsia rickettsii
Doxycycline, chloramphenicol
#buzzwords
DOC: Schizoephrenia
negative: 5HT2A antagonist olanzepine

positive sx:
DA2 antagonist
#buzzwords
DOC: sporothrix shenkii
Oral KI
#buzzwords
DOC: strep bovis
penicillin
#buzzwords
DOC: strep pneumo
penicillin/cephalosporin

vanc if meningeal
#buzzwords
DOC:UC
5-ASA, infliximab
#buzzwords
DOC: UTI prophylaxis
TMP-SMX
#buzzwords
DOC: Wegener's
Cyclosphsophamide, Corticosteroids
#buzzwords
Aortic Aneurysms
Dissecting: HTN
Abdominal: Atherosclerosis
Ascending: Marfan's
#buzzwords
Adult vs childhood meningitis
Adult
#buzzwords
Benign melanocytic nevus
spitz nevus
most common in first two decades
#buzzwords
Bleeding disorder with GpIb deficiency
Bernard-Soulier dz

(defective platelet adhesion to vWF)
#buzzwords
Breast Mass

most likely dx
Premenopausal: Fibrocystic Change

Post menopausal: Carcinoma
#buzzwords
Cardiac Tumor of Kids
Rhabdomyoma of Tuberous Sclerosis
#buzzwords
Endocarditis on both sides of mtiral valve
SLE
#buzzwords
Chronic Atrophic Gastritis

assoc
gastric carcinoma
#buzzwords
Most likely cause of constrictive pericarditis
3rd World: TB
1st world: SLE
#buzzwords
Most likely Coronary artery to thrombose
LAD > RCA > LCA
#buzzwords
Cause of Death in CML
blast crisis
#buzzwords
Most common cause of adult nephritic sro
Berger's IgA Dz
#buzzwords
Heart valve affected by bacterial endocarditis
IV drugs: tricuspid
Rheumatic Fever: Mitral > Aorta
#buzzwords
Top 3 causes of nosocomial pneumonia
Kleb, E coli, Pseudomonas
#buzzwords
Cause of osteomyelitis in IV drug abuser
s aureus & psuedomonas
#buzzwords
Most common ovarian tumor
Benign: Serous cystadenoma

Malignant: Serous cystadenocarcinoma
#buzzwords
Age of Pts with Leukemias
ALL; Child
CML: 30-60
AML ~60
CLL: >60
#buzzwords
Most common Lymphomas
Hodgkins: Nodular sclerosis (mixed cellularity)

Non-Hodgkins: Diffuse large cell
#buzzwords
Most common tumor in women
leiomyoma

estrogen dpt
not precancerous
#buzzwords
most common testiulcar
seminoma
#buzzwords
most common thyroid cancer
papillary carcinoma
#buzzwords
Henderson hasselbalch eqtn for determining blood pH
pH = pKa + log[HCO3-]/0.03 PCO2
#buzzwords
MAP
SV * HR
=
1/3 systolic + 2/3 diastolic
#buzzwords