Blood Bank Review Boc

Front 1

Naturally Occurring ABs

Back 1

ABO, Lewis, P1, MN, Lua

Front 2

Clinically Significant ABs

Back 2

ABO, Rh, Kell, Duffy, Kidd, SsU

Front 3

Cold ABs

Back 3

M, N, P1

Front 4

AB that usually only reacts in AHG

Back 4

Kell, Duffy, Kidd

Front 5

AB that can react in any phase of testing

Back 5

Lewis

Front 6

ABs that are enhanced by enzymes

Back 6

Rh, Lewis, Kidd, P1

(Rhotten, Kidd, Pinched, Lewis)

Front 7

ABs that are destroyed by enzymes

Back 7

M, N, Duffy

(daMN DUFFY)

Front 8

AB's that show dosage

Back 8

Rh (not D), MNS, Duffy, Kidd

Front 9

ABs that bind complement

Back 9

I, Kidd, Lewis

Front 10

ABs that cause in vitro hemolysis

Back 10

ABO, Lewis, Kidd, Vell, some P1

Front 11

AB that commonly causes delayed transfusion reaction

Back 11

Kidd

Front 12

AB associated with PNH

Back 12

Anti-P

Front 13

Associated with Cold Agglutinin Disease

Back 13

Anti-I

Front 14

What is the type of transfusion reaction is this:

1 Hr after administration pt has Hb in urine and serum, mixed field DAT, decreased haptoglobin, HB, and HCT

Back 14

Acute hemolytic transfusion reaction

Front 15

What is the cause of Febrile Transfusion reactions? What type of product should be administrated to this patient?

Back 15

Caused by Anti-leukocyte ABs or cytokines

Future transfusions should be with leukoreduced components.

Front 16

What is the cause of Allergic Transfusion reactions?

Back 16

Foreign plasma proteins

Front 17

What is the cause of Anaphylactic Transfusion reactions? What kind of product should this person receive in the future?

Back 17

Anti-IgA in IgA deficient recipient.

Should receive washed products in the future

Front 18

Shelf life of product with CPD, CP2D, and CPDA-1 anticoagulants?

Back 18

CPD and CP2D= 21 days

CPDA-1= 35 days

Front 19

What is the shelf life of RBCs with Additive Solution?

Back 19

42 Days

Front 20

1 Unit of RBC increases Hb and HCT by how much?

Back 20

Hb: 1 g/dL
HCT: 3%

Front 21

Shelf life of frozen RBCs in <65C? After deglyc?

Back 21

Frozen:10 years

After Deglyc: 24 hours (stored at 1-6C)

Front 22

Shelf life of washed RBC and what are the indications?

Back 22

Shelf life: 24 hours after washing

Indications: History of severe allergic rxn (IgA, other plasma proteins)

Front 23

RBCs leukoreduced: Shelf life, indications, and QC.

Back 23

Shelf life: Closed system same as RBC, Open system 24 hrs

Indications:History of febrile rxn

QC: must retain 85% of original RBCs and <5x10^6 WBCs

Front 24

RBCs irradiated: Shelf life, indications

Back 24

Shelf life: original outdate or 28 days from irradiation, which ever comes first.

Indications: immunodeficiency, malignancy, bone marrow, tx from relative, neonatal, intrauterine.

For prevention of GVHD, kills donor T cells

Front 25

FFP: Storage temp, Shelf life, Indications

Back 25

Storage temp: <-18 C, after thawing 1-6 C

Shelf life: Frozen 12 mo., Thawed 24 hr

Indications: deficiency of coag factors

Front 26

Cryo: Storage temp, Shelf life, Indications, QC

Back 26

Storage Temp: Frozen <-18 thawed RT

Shelf life: Frozen 12 mo. thawed 6 hours (non sterile pooled 4)

Indications: Fibrinogen and factor XIII deficiencies

QC: >80 IU Factor VIII and >150 mg fibrinogen

Front 27

Platelets: Storage temp, Shelf life, Indications QC

Back 27

Storage: 20-24 C

Shelf life: 5 days from collection (4 hr after pooling)

Indications: Severe thrombocytopenia or abnormal platelet function

QC: 40-70 mL plasma, >5.5x10^10 plt, pH>6.2

Front 28

Apheresis platelets: Storage temp, Shelf life, Indications, QC

Back 28

Storage temp: 20-24C

Shelf life: 5 days with agitation

Indications: Severe thrombocytopenia or abnormal platelet function

QC: >3.0x10^11 plt

Front 29

What is the purpose of leukoreduction?

Back 29

1.Decrease WBC to decrease febrile nonhemolytic transfusion reactions

2.Transmission of CMV

3.HLA alloimmunization

Front 30

What is increased during RBC Storage Lesion

Back 30

-Lactic Acid

-Plasma K+

-Plasma Hb

-Microaggragates

Front 31

What is decreased during RBC Storage Lesion?

Back 31

-ATP

-2,3 DPG

-pH

-Glucose

-Viable Cells

-Labile coag factors

Front 32

RBC storage lesion shows what type of O2 shift?

Back 32

Shift to the left ( inc Hb/O2 affinitty, dec O2 delivery to tissues)

Front 33

FFP must be separated from RBCs and frozen solid at less than or equal to -18 degrees Celsius within _______ hours of collection.

Back 33

8

Front 34

The majority of Lea antibodies are....

Back 34

IgM

Front 35

What is the most prudent step to follow to select units for cross-match after recipient antibodies have been IDENTIFIED?

Back 35

antigen type patient cells and any donor cells to be cross-matched

Front 36

A 300 µg dose of RhIg can suppress immunization to how many mL of D-positive whole blood?

Back 36

30 mL

Front 37

A patient's serum reacts with all reagent red cell samples. The autocontrol is negative. An alloantibody to a high incidence antigen is suspected. Which of the following would be most likely to be a compatible donor:

Parents, Siblings, Children, Random Donor?

Back 37

Siblings

Front 38

_______________ is the gold standard for anti-HIV-1 confirmation.

Back 38

Western Blot

Front 39

Criteria for allogenic blood donation

Back 39

Age: 16

Hb/HCT: >12.5 g/dL, >38%

Temp: <37.5C (99.5F)