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129 Cards in this Set

  • Front
  • Back
The donor history questionnaire was developed by ?
AABB (American Association of Blood Banks)
What are the 3 steps in the donor screening process?
1. registration 2. health history 3. physical exam
A donor applicant who has received a tattoo or permanent makeup at a facility that it not state regulated must be deferred for how long?
1 year
A donor applicant with a history of hepatitis after his 11th birthday will be deferred for how long?
permanently deferred
Donor applicants taking Warfarin/Coumadin will be deferred for how long?
1 week
Donor applicants who have recently received a Hepatitis B vaccine will be deferred for how long?
28 days
A donor applicant who tests positive for hepatitis B surface antigen will be deferred for how long?
permanently deferred
A donor applicant who tests positive for hepatitis B antigen on more than one occasion will be deferred for how long?
permanently deferred
Donor applicants who have recently received a vaccine for viruses OTHER THAN German measles, Chickenpox, or hepatitis will be deferred how long?
2 weeks
A donor applicant with past or present lab evidence of hepatitis C virus will be deferred for how long?
permanently deferred
A donor who has received a rabies vaccine after an animal bite must be deferred for how long?
1 year
Donor applicants who have recently received the German measles or Chickenpox (Varicella-zoster) vaccines will be deferred how long?
4 weeks
Donor applicants taking bovine insulin will be deferred for how long?
indefinitely
A donor applicant must wait how long to donate blood after pregnancy?
6 weeks
A donor applicant with past or present lab evidence of human T-cell lymphotropic virus will be deferred for how long?
permanently deferred
Donor applicants who have hepatitis B immune globulins will be deferred for how long?
1 year
A donor applicant with past or present lab evidence of HIV infection will be deferred for how long?
permanently deferred
A donor applicant with a history of babesiosis or Chagas disease will be deferred for how long?
permanently deferred
A donor applicant with a history of malaria or who has lived in a country for 5 consecutive years or more where malaria is endemic will be deferred for how long?
3 years
A donor applicant with a family history of CJD/Mad Cow disease will be deferred for how long?
permanently deferred
A donor applicant that has traveled to an area where malaria is endemic will be deferred for how long?
1 year after departure
A donor applicant who has lived 3 months or more in the U.K. from 1980-1996 will be deferred for how long?
indefinitely
Donor applicants taking Accutane will deferred for how long?
1 month
A donor applicant who has received dura mater or human pituitary growth hormone will be deferred for how long?
permanently deferred
A donor applicant who has lived 5 years or more in Europe from 1980 to the present will be deferred for how long?
indefinitely
Donor applicants taking Propecia will be deferred for how long?
1 month
Any donor applicant who has received a blood transfusion or human tissues must be deferred for how long?
1 year
A donor applicant who has used a needle to self-administer nonprescription drugs will be deferred for how long?
permanently deferred
Donor applicants taking aspirin will be deferred for how long?
2 days FOR PLATELET DONORS ONLY
Donor applicants taking Plavix will be deferred for how long?
14 days FOR PLATELET DONORS ONLY
A donor applicant who has been incarcerated for more than 72 hours must be deferred for how long?
1 year
The antecubital site where a blood donation is to be made from must be sterilized with 10% __ or .7% __.
10% Betadine (povidone-iodine) or 0.7% iodine (aqueous iodophor)
What size needle is normally used during a blood donation?
16 gauge
If a donor begins to complain of weakness, dizziness, pallor, nausea and vomiting, what should you do?
1. remove needle and tourniquet 2. elevate legs above head 3. apply cold compresses to forehead and back of neck
If a donor faints (syncope) what should you do?
Apply cold compresses on back of neck.
If a donor has a hematoma, what should you do to minimize the bruise?
apply pressure for 7-10 mins, then ice for 5 mins
If a donor begins having convulsions while donating blood, what should you do?
1. call for help 2. prevent donor from falling or injuring himself 3. ensure donor has adequate airway
The donor should notify the blood center if they experience any reactions from their blood donation within how long?
2 weeks
Donations made to the general population are called ?
allogeneic
Donations made for the donor's personal use are called ?
autologous
Donations contributed for use by a specific person other than the donor are called ?
directed donations
What are the 5 advantages of an autologous blood donation?
1. prevents transmission of disease 2. prevents alloimmunization 3. supplements the blood supply 4. prevents febrile and allergic reactions 5. reassures the patient
What are the 5 disadvantages of making an autologous blood donation?
1. inventory control 2. preoperative anemia 3. increased cost 4. high wastage 5. increased incidence of adverse reaction to donation
When blood is drawn and stored before the anticipated date of surgery, this is called a __ donation.
preoperative
Removing units of blood at the beginning of surgery and reinfusing them at the end of surgery is called a __ donation.
normovolemic
When a medical device washes, filters, and concentrates blood during an operation, this is called __ __.
blood recovery
A donor applicant's hemoglobin must be at least __ g/dL to donate.
12.5 g/dL
A donor applicants hematocrit must be at least __% to donate.
38%
A donor applicants temp must be less than or equal to __ degrees Celsius.
37.5
A donor applicants must be at least __ years old to donate.
17, or in accordance with state law (18 in Delaware)
To make a preoperative donation, a patient's hemoglobin must be at least __ g/dL.
11
To make a preoperative donation, a patient's hematocrit must be at least __%.
33
A patient can make a preoperative donation up to how many hours before an operation?
72
You must wait how many days after a blood donation to make another one?
56 days
When blood components are separated and the remaining blood is returned to the donor, this is called ?
apheresis
When white blood cells are separated for a donation, this is called ?
leukapheresis
Plateletpheresis donations must be made at least how many hours apart and how many times per week?
48 hours apart, no more than twice per week
What immunoglobulin levels are monitored when making a donation for frequent plasmapheresis?
IgG and IgM
After donating for red cell apheresis, deferral for making another donation is how long?
16 weeks
Testing blood for ABO, D type, and antibody screening is what category of test?
Immunohematologic testing
Testing blood for infectious agents is called what category of testing?
infectious disease screening
NAT stands for?
nucleic acid test
What does HBsAg stand for?
Hepatitis B surface antigen
What does anti-HBc stand for?
antibody to Hepatitis B core
When testing for Trypanosoma cruzi (Chagas disease) we are really looking for what antibody?
IgG antibody to T. cruzi
HTLV stands for?
Human T-cell lymphotropic virus
Certain people require blood that has been tested for CMV. What are the 3 groups of people?
1. immunocompromised 2. babies 3. pregnant women (or women of child bearing age)
What 4 tests are performed on blood to check for hepatitis?
1. HBsAg (hepatitis B surface antigen) 2. anti-HCV (antibody to hepatitis C virus) 3. Anti-HBc (antibody to hepatitis B core) 4. HCV NAT (hepatitis C virus nucleic acid test)
RPR stand for?
rapid plasma reagin
Syphilis is caused by what infectious agent?
Treponema pallidum
What test is used to check blood for syphilis? What test is used to confirm?
RPR test, confirmed with Fluorescent treponemal antibody adsorption test
What does EIA stand for?
Enzyme-linked Immumosorbent Assay
Indirect EIA detects what?
antibodies
Sandwich EIA detects what?
antigens
What is the advantage of a NAT over other tests?
NAT can detect VERY low numbers of viral copies in plasma, even before antibodies appear
Which kinds of hepatitis can be transmitted by IV?
B, C, D
HBsAG (hepatitis B surface antigen) tests for a __ on the viral surface that indicates the patient has been infected.
protein
What antibody appears in a patient after HBsAG but before symptoms appear?
anti-HBc (antibody to hepatitis B core antibody)
What makes a retrovirus different from a DNA virus?
A retrovirus has reverse transcriptase that allows the virus to convert RNA to DNA and integrate the new DNA into the cell
HTLV-1 is associated with ?
adult T-cell leukemia
Even after blood has been leukareduced, some WBCs remain and the patient can still be infected by __.
HTLV-1
What 4 infectious agents can trigger a look-back investigation?
1. hepatitis 2. HIV 3. HTLV 3. WNV
Chagas disease is the result of what infectious agent?
Trypanosoma cruzi
Trypanosoma cruzi is transmitted by what bug?
Reduviid bug
What substance supports ATP generation by the glycolytic pathway?
dextrose
What substance acts as a substrate for red cell ATP synthesis?
adenine
What substance prevents coag by chelating calcium and protects donated RBC membranes?
citrate
What substance prevents an excessive decrease in donor blood pH?
sodium biphsophate
What substance is an osmotic diuretic that acts as a membrane stabilizer?
Mannitol
CPD and CP2D can allow blood to be stored for how many days?
21
CPDA-1 can allow blood to be stored for how long?
35 days
Additive solution AS-5 can allow blood to be stored for how long?
42 days
CPD stands for?
Citrate-phosphate-dextrose
What increases when blood is stored?
potassium and plasma hemoglobin due to RBC lysis
RBC ATP and 2,3 DPG go (up or down?) once blood has been stored?
down
Platelet-rich plasma (PRP) is expelled into a satellite bag when whole blood undergoes a (light or heavy?) spin.
light
Platelets are separated from plasma when PRP is spun at a (heavy or light?) spin?
heavy
Plasma can be further processed into __ __ __ during a heavy spin.
fresh frozen plasma (FFP)
FFP (fresh frozen plasma) can be processed into __.
cryoprecipitate
A unit of whole blood increases a recipient's hemoglobin by how much?
1g/dL
A unit of whole blood increases a recipient's hematocrit by what percent?
3%
RBC component must be stored at what temp?
1-6C
Frozen RBCs must be stored at what temp?
-65C or lower
Frozen RBCs remain viable for how long?
10 years
Deglycerolized or washed RBCs must be stored at 1-6C and are good for how long?
24 hours
Irradiated RBCs must be stored at what temp?
1-6C
Irradiated RBCs are good for how long?
28 days from irradiation or their pre-irradiation expiration date
Fresh frozen plasma (FFP) must be stored at what temp?
-18C or less
If stored at -18C, FFP is good for how long?
1 year
Once thawed, FFP and PF24 are good for how long?
24 hours
Leukocyte reduced apheresis platelets should be stored at what temp?
20-24C
Leukocyte reduced apheresis platelets are good for how long?
5 days
Cytokines produced by WBCs can cause _ reactions.
febrile reactions
Cytokines produced by leukocytes can cause what 3 reactions?
1. fever 2. shaking 3. chills
Removing WBCs does not prevent GVH disease (graft VS host) but what does?
irradiation
The final RBC apheresis must have at least __ g of hemoglobin and a minimum volume of __ mL.
51g, 153mL
Automatic collection of 1 unite of apheresis RBCs takes place once every __ weeks.
8
What do we wash RBCs with to remove plasma proteins that might cause allergic, febrile, or anaphylatic reactions?
saline
GVH disease is a reaction to __ on T cells.
HLAs
Which is better: Apheresis platelets or pooled platelets?
apheresis
FFP and PF24 contain all coag factors, but PF24 is deficient in what coag factor?
8
Patients in need of which 4 factors can be given FFP?
II, V, X, XI
What 6 reasons are there for giving someone FFP?
1. coag deficiency 2. mass transfusion 3. warfarin 4. therapeutic plasmapheresis 5. live disease and factor deficiency 6. DIC
FFP and PF24 thaw in __ mins and should be stored at what temp?
30-45 mins, 1-6C
If FFP and PF24 have not been transfused within 24 hours, it can be stored at 1-6C and used within __ days.
5
Thawed plasma cannot be used to replace factor __.
8
CRYO must have __ mg of fibrinogen and __ international units of factor __ per unit.
150mg, 80 IU, factor 8
CRYO contains what factors?
VWF, fibrinogen, 8, fibronectin, 13
AABB standards required all facilities to convert to __ by May 1, 2008.
ISBT 138