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71 Cards in this Set

  • Front
  • Back
Chagas dz
Trypanosoma cruzi
First line for Chagas
Nifurimox
Second line for Chagas
Benznidazole
African sleeping sickness
T. bruci
T. gambiense
T. rhodesiense
1st line treament of early stage (no CNS involvement) sleeping sickness if caused by T.b. or T.g.?
Suramin + pentamidine or eflornithine
2nd line treatment of early stage sleeping sickness?
Pentamidine (effective against both T.b. and T.g.
1st line treatment of early stage sleeping sickness if caused by T.r.?
Suramin
1st line treatment for late stage (CNS involvement) sleeping sickness (by any of the 3)
Melarsoprol
2nd line treatment for late stage sleeping sickness?
Eflornithine (effective against only T.b. and T.g.)
Leishmaniasis
American cutaneous
Mucocutaneous
Viseral (kala azar)
Cutaneous (oriental sore)
Cause of Leishmaniasis (cutaneous and mucocutaneous)
Leshmania braziliensis
L. mexicana
Cause of Viseral Leshmania
L. donovani
Cause of cutaneous Leshmania
L. tropica
1st line treament for american cutaneous and mucocutaneous infection?
Second line?
1st: Sodium stibogluconate
2nd: Amphotericin B
1st and 2nd line treatment for viseral leshmania
1st: Sodium stibogluconate
2nd: pentamidine
1st line treatment for cutaneous (oreintal sore) leshmania
Sodium Stibogluconate
Amebiasis
Entamoeba histolytica
1st line treatment for Amebiasis
Iodoquinol
2nd line treatment for Amebiasis
Paromomycin
Any other drugs we can use for Amebiasis
Diloxanide furoate (DF)
Alternate 1st line therapy for Amebiasis (thought you were done didn't you)
Alternate 2nd line?
1st: Metronidazole + iodoquinol

2nd: Paromomycin + DF
Babesiosis- name that organism
1st line therapy
Babesia microti
Clindamycin + quinine sulfate
Cyclosporosis- name that organism
1st line therapy
Cyclospora (clever huh?)

TMP/SMX
Cryptosporidiosis organism and 1st line therapy
Cryptosporidium
Paromomycin
Giardiasis- name that organism
1st line therapy
2nd line therapy
Giardia lamblia
1st: Metronidazole
2nd: Albendazole
Isosporiasis
1st line therapy
Isospora belli

TMP/SMX
Microsporidiosis
1st line
2nd line
Microsporidia
1st: Atovaquone
2nd: Albendazole
PCP
1st line
Pneumocystis carinii

TMP/SMX
2nd line for PCP infection
Pentamidine isethionate or atovaquone
1st line treatment for acute Toxoplasma gondii infection
Pyrimethamine + Sulfadiazine
2nd line treatment for acute T. gondii infection
Pyrimethamine + Clindamycin or Atovaquone
*With pyrimethamine need to give folic acid (leucovorin) to protect bone marrow
1st line prophalaxis for T. gondii
TMP/SMX
2nd line prophalaxis for T. gondii
Pyrimethamine + dapsone
1st line treatment for Trichomonas vaginalis infection
Metronidazole
2nd line treatment for Trichomonas vaginalis infection
Tinidazole
Ascaris lumbricoides
First line
Mebendazole or pyrantel pamoate
Ascaris lumbricoides
Second line
Albendazole or invermectin
Capillaria phillipinesis
first line
Albendazole
Capillaria phillipinesis
second line
Mebendazole
Dracunculus medinensis
First line
Second line
Metronidazole
Use second line only for extraction of the worm
Enterobius vermicularis
First line
Mebendazole
E. vermicularis
Pyrantel pamoate or albendazole
Wucheria bancrofti
Diethylcarbamazine or ivermectin
Brugia malayi
Diethylcarbamazine or ivermectin
Dipetalonema perstans
Diethylcarbamazine or ivermectin
Loa loa
Diethylcarbamazine
Onchocerca volvulus
1st
2nd
1st: Ivermectin
2nd: DEC
Necator americanus (hookworm)
1st
Mebendazole or albendazole
Ancylstoma duodenale (hookworm)
1st
Mebendazole or albendazole
Necator americanus (hookworm)
pyrantel pamoate
Ancylstoma duodenale (hookworm)
2nd
Pyrantel pamoate
Cutaneous larva migrans
1st
2nd
1st: Albendazole
2nd: Thiabendazole
Stongyloides stercoralis
1st
2nd
1st: Albendazole
2nd: Thiabendazole or ivermectin
Toxocara spp.
1st: Albendazole
2nd: Thiabendazole or ivermectin
Trichinella spiralis
1st
2nd
1st: Albendazole
2nd: Thiabendazole
Trichuris trichiura
1st
2nd
1st: Mebendazole
2nd: Albendazole or ivermectin
Taenia saginata
1st
2nd
1st: Praziquantel
2nd: Niclosamide
T. solium
1st: Praziquantel
2nd: Niclosamide
Neruocysticercosis
1st
2nd
1st: Albendazole
2nd: Praziquantel
Diphyllobothrium latum
1st
2nd
1st: Praziquantel
2nd: Niclosamide
Hymenolepis nana
1st
2nd
1st: Praziquantel
2nd: Niclosamide
Echinococcus granulosus
1st
2nd
1st: albendazole
2nd: Surgical resection
Echinococcus multilocularis
1st
2nd
1st: albendazole
2nd: Surgical resection
Schistosoma hematobium, japonicum, mansoni, mekongi
1st
2nd
1st: Praziquantel
2nd: Oxamniquine for S. mansoni
Fasciolopsis buski
Praziquantel
Heterophyes heterophyes
Praziquantel
Metagoniums yokogawai
Praziquantel
Clonorchis sinensis
Praziquantel
Opisthorchis felineus and viverrini
Praziquantel
Fasiciola hepatica
1st
2nd
1st: Triclabendazole
2nd: Bithionol
Paragonimus spp.
Praziquantel