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80 Cards in this Set
- Front
- Back
Monohybrid cross
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A cross that differs in only one characteristic
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For each characteristic an organism inherits how many alleles?
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2
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An organisms physical traits are called?
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phenotype
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An organisms genetic makeup is called
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Genotype
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When an organism has identical alleles for a gene it is called
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homozygous
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when an organism has different alleles for a gene it is called
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Heterozygous
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What are the two hypotheses for gene assortment in a dihybrid cross?
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-Dependant assortment
-Independent assortment |
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Most human genetic disorders are what?
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Recessive
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Achondroplasia is a form of what?
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Dwarfism
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The immune system produces what?
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Blood proteins
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What can happen if blood cells of a different type enter the body?
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Clotting
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Genes located close together on a chromosome are known as?
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Linked genes
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An organism's genotype is the sequence of what?
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nucleotide bases in DNA
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What happens in Transcription?
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DNA to RNA
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What happens in Translation?
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RNA to Protein
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What is the second phase of Transcription?
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elongation
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What is the 3rd phase of transcription?
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termination
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what organelles make polypeptides?
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Ribosomes
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What is the first phase of translation?
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Initiation
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Elongation continues until the ribosomes reach what?
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a stop codon
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In eukaryotic cells, where does transcription and translation take place?
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Transcription=in the nucleus
Translation= in the cytoplasm |
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any change in the nucleotide sequence of DNA is known as?
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a mutation
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What are the two general categories of mutations?
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Insertion and Deletions
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Control sequences
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stretches of DNA that coordinate gene expression
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a cluster of genes with related functions is called?
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an operon
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What were Mendel's four hypotheses?
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1. There are alternative forms of genes called alleles
2. For each characteristic, an organism inherits 2 alleles, one from each parent 3. Alleles can be dominant or recessive 4. Gametes carry only one allele for each inherited characteristic |
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Mendel's law of segregation states that
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Two members of an allele pair segregate from each other during the production of gametes.
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What are 2 characteristics of Homologous chromosomes?
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-Have genes at specific loci
-Have alleles of a gene at same locus. |
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PP and aa would be examples of what type of allele?
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Homozygous
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Bb is an example of what type of allele?
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Heterozygous
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3 purple : 1 white, is showing what type of ratio?
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Phenotypic
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1PP: 2Pp: 1pp is showing what type of ratio?
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Genotypic
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Mendel's law if independent assortment state that?
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Each pair of alleles segregates independently of the other pairs during gamete formation.
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A family pedigree shows what?
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the history of a trait in a family
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Incomplete dominance
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When hybrids have an appearance in between the phenotypes of the two parents
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ABO blood groups in Humans are an example of what?
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Multiple alleles
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When alleles exhibit codominance it means what?
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Both alleles are expressed in the phenotype.
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The behavior of what during meiosis and fertilization account for inheritance patterns.
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Chromosomes
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Genes located on a sex chromosomes are called?
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Sex-linked genes
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What are the 4 nucleotides found in DNA?
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thymine, cytosine, adenine and Guanine
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What are the 4 nucleotides found in RNA?
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Uracil, cytosine, adenine and guanine
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What type of bonding is found in DNA?
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Hydrogen
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The enzyme known as the "unwinder" of DNA is called what?
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Helicase
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What holds open the DNA during reproduction?
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Single stranded proteins
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Each segment or "chunk" in DNA replication is known as what?
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Okazaki fragments
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Genetic Information in DNA is transcribed into RNA and then translated into what?
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polypeptides
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Triplets of bases specify all the what?
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Amino Acids
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Sequences of 3 bases are called what?
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Codons
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What is the Language of nucleic acids in DNA?
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Sequences of nucleotide bases
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What is the result of transcribed DNA
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RNA
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We call the set of rules relating to nucleotide sequence to amino acid sequence what?
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genetic code
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What is the enzyme that makes protein?
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RNA polymerase
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The "Start transcribing" signal is a nucleotide sequence called a what?
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Promoter
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What two things happen during transcription?
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-RNA polymerase attaches to the promoter
-RNA synthesis begins |
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What happens during elongation?
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The RNA strand grows longer
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What happens during termination?
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RNA polymerase reaches a sequence of DNA bases called a terminator.
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RNA processing includes what 3 things?
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-Adding a cap and tail
-Removing introns -splicing exons together |
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Which exits the nucleus, exons or introns?
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Exons
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what does the m and t mean in mRNA and tRNA?
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m= messenger
t= transfer |
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What 3 thing does tRNA do?
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-Acts as a molecular interpreter
-carries amino acids -matches amino acids with codons in mRNA using anticodons. |
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What does tRNA use to match codons in mRNA?
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anticodons
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What is the last letter in a codon called?
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Wobble
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What 3 things does the first phase of Translation bring together
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-the mRNA
-the first amino acid with its attached tRNA -The two subunits of the ribosome |
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mRNA's cap and tail help it bind to what?
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the ribosome
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What happens during step one of elongation?
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Codon recognition, the anticodon of an incoming tRNA pairs with the mRNA codon.
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What happens during the second step of elongation?
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peptide bond formation, the ribosome catalyzes bond formation between amino acids
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What happens during the third step of elongation?
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Translocation, a tRNA leaves the P site of the ribosome. The ribosome moves down the mRNA
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Mutations can result from what two things?
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-errors in the DNA replication
-Physical or chemical agents called mutagens |
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What can alter gene expression based on environmental factors?
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Bacteria
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A cluster of genes with related functions, including the control sequence are know as?
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An operon
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What are the two parts of an operon?
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Promoter, operator
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The site where the transcription enzyme initiates transcription
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promoter
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RNA polymerase binds to what site?
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a promoter
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The regulatory part of an operon is the?
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operator
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what is an operator?
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a DNA sequence between the promoter and the enzyme genes
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What acts as the on/off switch for genes?
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the operator
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what sits on the operator to act as a road blocker?
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The repressor
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The many proteins involved in transcriptional regulation in eukaryotes are collectively known as?
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transcription factors
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Transcription factors bind to DNA sequences called?
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enhancers
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What do repressor proteins do? How do they do this?
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inhibit transcription, by binding to DNA sequences called silencers.
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