Biochem Test

Front 1

1. 25-OH D3 is called

Back 1

Calcidoil

Front 2

Proteoglycans differ fromglycoproteins in

Back 2

a. Sugars modified by sulpho group /o:p>

Front 3

1. The cofactor of Prolylhydrioxylase and lysyl hydroxylase is --~

Back 3

Fe2

Front 4

Whichamino acid is melanin produced from~)|

Back 4

Tyrosine

Front 5

1. Vitamin K is animportant cofactor participating inkp_inclu~*

Back 5

a. Glutamic acidcarboxylation ~*

Front 6

1. Inositol

Back 6

Cyclic polyalcohol

Front 7

The nervous tissue does not oxidize

Back 7

Fatty acids

Front 8

1. Which of the followingamino acids contain an R-group that can function as a buffer at pH 7,0?e.com,homesan~*

Back 8

Hisitidine

Front 9

1. Regarding α-helix, all the statements are correct, except: /~*i*

Back 9

a. It is the predominantstructure of collagen ~*

Front 10

1. Isoenzymes are: ent-->

Back 10

a. Enzymes of differentstructure catalyzing the same reaction

Front 11

1. Which citrate-cycle enzyme is localized in the innermitochondrial membrane -->

Back 11

a. Succinate dehydrogenase

Front 12

1. Which of the followingsubstances belongs to the membrane lipids

Back 12

Lecithins

Front 13

1. Select the incorrectstatementET

Back 13

a. Oxidation of thesecondary hydroxyl group in the molecule of oxalacetic acid forms malic acid xCT

Front 14

1. Which of the followingcompounds is not a hexose>

Back 14

a. Ribose (Aldose and Pentose)

Front 15

1. The isoelectric pointof glutamic acid is 3,2. What is its charge at pH=1,8~*

Back 15

Positive

Front 16

1. What is the product of glucose oxidation at C1 ment-->

Back 16

a. Gluconolactone +wasserstoffperoxide esan~*

Front 17

1. Which statement is correct? (alanine,leucine,isoleucine,proline,phenylalanine ,glycine also unpolar) esan~*

Back 17

a. Valine is a hydrophobicamino acid p><~*

Front 18

1. Which of the followingheterocycles are comprised in FAD structure? 5%T

Back 18

a. Isoalloxazine, purine,tetrahydrofuran

Front 19

1. An irreversible enzymeinhibitor is>

Back 19

a. Usually bound to theenzyme covalent bond

Front 20

1. Check the correctstatement(s) about dispersion systems:

Back 20

a. The particles ofanalytic disperses are observable by means of an electron microscopeFragmen~*

Front 21

1. A competitive inhibitor>

Back 21

a. Binds to the enzymeactive site*

Front 22

1. If a globular protein is embedded in a lipid bilayer, which of the following amino acids can be in contact with interior of the bilayer?

Back 22

a. Phenylalanine~*

Front 23

1. 2,3 – biophosphoglycerate \[taw*r%T

Back 23

a. Shifts the saturationcurve to the rightr-fa~*

Front 24

36. Heme comprises in its structure: rphan; font~)

Back 24

Pyrrole

Front 25

1. Phosphatidic acid isthe intermediate in synthesis of ??ophosphogly~*

Back 25

Triacylglycerol

Front 26

1. Reaction catalyzed by acetyl-CoA carboxylase produces:

Back 26

a. Malonyl-CoA>~*

Front 27

Writethe structural formula and name acompound formed by the reductionof pyruvate.eme-font:mino~)

Back 27

lactic acid CH3CHOHCOOHof

Front 28

Writethe formula and the name of thesubstance that is produced byoxidation of hydroquinone!2~7)

Back 28

1. p-benzoquinoneo~jh*

Front 29

glycine

Back 29

)does not have an asymmetric carbon

Front 30

One typical coenzymes oxidoreductases are:t

Back 30

NADH

Front 31

Ribose

Back 31

Aldose

Front 32

electrophilic group for enzymes M~I)u

Back 32

Metal complexes

Front 33

)Example anaplerotic reaction (or agent in anapleroticresponse)-font:|~x)u

Back 33

c) pyruvate carboxylase

Front 34

What causes the tryglyceride accumulation in the liver?

Back 34

a. Insuline resistance

Front 35

1. Glutamine is mainly produced by the:o:p~*

Back 35

a. Skeletalmusclesy>~*

Front 36

1. Which of the following belog to the positive acute phase reactants -> <~*

Back 36

a. CRP,procalcitonin

Front 37

1. The release of free fatty acids fromadipose tissue is not increased by:

Back 37

Insulin

Front 38

1. Which of the following collagen types do not belong to fibrillary collagens? >

Back 38

Type 4

Front 39

1. Thyroxine if formed by condensation of two molecules of: J~N*

Back 39

Diiodotyrosine

Front 40

1. In the erythrocytes, the glycolysis end products is:l>J~N*

Back 40

a. Lactatel>J~N*

Front 41

1. Formation of bilirubin is accompanied by the release of: J~N*

Back 41

Co

Front 42

1. Regulation of β-oxidation is accomplished via:

Back 42

a. CPT I inhibition bymalonyl-CoA.

Front 43

1. Which enzyme is activated in the post-absorptivestate?-weiI~M*

Back 43

Glycogen phosorylase

Front 44

1. Theconjugated bilirubin:[{"pro4~0*l

Back 44

a. Is the bilirubin conjugated withglucuronic acid

Front 45

1. AMP-activated protein kinase cebook.com&~"*l

Back 45

a. Inhibits anabolic processes and activatesthe catabolic ones[T

Front 46

1. Whichpathway is activated by insulin?&~"*l

Back 46

a. Synthesis of fatty acidsygree0~4*l

Front 47

1. Y-Glutamyl transferasen"'> &~"*l

Back 47

a. Is usually increased during bile ductobstruction^

Front 48

1. Which of the following substrates is the main energy source of the heart? ",2.34,"http:!~%*l

Back 48

a. Fatty acids /p>

Front 49

1. Hydrogenperoxide is decomposed by.com&~"*l

Back 49

Catalase

Front 50

1. Nitric oxide (nitrogen monooxide) is generated from

Back 50

a. Arginine /p>

Front 51

1. Inposthepatic jaundice there is k.com&~"*l

Back 51

a. Increased level of bilirubin in urine ent-->

Front 52

1. NADPHfor the synthesis of fatty acids originates from 4IQIDAQAB","man ~$*l

Back 52

a. Pentose phosphate pathwayZT

Front 53

1. Acetyl-CoA is transported from mitochondria in the form of rce-https", ~$*l

Back 53

Citrate

Front 54

1. Sorbitolis formed by %~!*l

Back 54

a. Glucose reduction at firstcarbon (C1)n>~O*

Front 55

1. Whichhormone does NOT activate gluconeogenesis?

Back 55

a. Insulin/body>~A*

Front 56

1. Triglycerols in VLDL are cleaved by tr.com/!~%*l

Back 56

a. Lipoprotein lipasey>~A*

Front 57

1. Anucleotide consists of 2150472.38726&~"*l

Back 57

a. Purine or pyrimidine base, sugar and phosphate group

Front 58

1. Heme binds to globin by means of ,["htt&~"*l

Back 58

a. Coordinate bound to a distal histidinebody>

Front 59

1. Cysteine can be synthesized from methionine and "mode"'~#*l

Back 59

Serine

Front 60

1. Dolichol is needed in biosynthesis of t&~"*l

Back 60

a. Glycoproteins with N-glycosidic bondsdy>

Front 61

1. Whichof the following does NOT belong to the symptoms of iron deficiency?tnmnstr.com/!~%*l

Back 61

a. Increased level of ferritin in theblood

Front 62

1. beta-oxidationtakes place in the87268&~"*l

Back 62

a. mitochondriamen~A*

Front 63

1. Majorfunctions of apoproteins in lipoproteins are NOT: i

Back 63

a. Antigenic determinants of lipoproteins

Front 64

1. Lysosomal storage disease are cause by enzymatic deficiencies in degradation of "~&*l

Back 64

a. Sphingolipids

Front 65

1. The affinity chromatography of mRNA utilizes the affinite between: sources\\c~*l

Back 65

a. the polythymidylate tail of mRNA and a matrix-bound polyadenylate

Front 66

1. what is oncoticpressure?://~*l

Back 66

osmotic pressure of colloid dispersion

Front 67

1. thetoxicity of heavy metals is caused mainly by their binding to: "pkp~*l

Back 67

thiol groups

Front 68

1. α-D-glucose and β-D-glucose are: facebook ~ *l

Back 68

anomers

Front 69

1. Whichstructure is not lost under protein denaturation:ZT

Back 69

primary":215900},{\o~kB)

Front 70

1. Transmittance is: https", ~ *l

Back 70

the ratio of intensities of outgoing and incoming light

Front 71

1. Thecofactor deployed in formyl group transfer is:

Back 71

tetrahydrofolic acid

Front 72

1. Whichmonosaccharides are comprised in the structure of lactosef72~*

Back 72

Glucose and galactose

Front 73

1. Planar(thin-layer) chromatography is used

Back 73

Mainly for quantitative component determination

Front 74

1. What isthe fluorescence quenching?

Back 74

Decreasing the fluorescence intensity rgin:70.85pt ~D)

Front 75

1. Cholesteroland carotenes belong to

Back 75

Isoprenoids1~B)

Front 76

1. Absorbanceis

Back 76

Decadic logarithm of the incoming to outgoing light intensities rat1.

Front 77

1. Tyrosinecomprises~*

Back 77

Phenol {size:61~B)

Front 78

1. Reactiontypical for aromatic ring isoT

Back 78

Electrophilic substitution92.0pt;~E)

Front 79

1. Inelectrophilic substitution aromatic ring acts as:

Back 79

Lewis acid

Front 80

1. Fourcarbon monocarboxylic acid is called:

Back 80

butanoic

Front 81

1. Fumarate is an isomer of: tps", ~*

Back 81

Malate

Front 82

1. Phosphatidic acid is composed of: ~*

Back 82

a. glycerol, 2 fatty acyls and phosphate C~F*)

Front 83

1. Themelting point of DNA increases if there is:

Back 83

high content of cytosine.0pt;t~qE)

Front 84

1. What isthe Oxidation number of carbon in formaldehyde*

Back 84

0

Front 85

1. What isthe oxidation number of carbon in methanol?

Back 85

2-

Front 86

1. The nucleobase is bound to deoxyribose in DNA by: ~*

Back 86

N-glycosidic bond1{~~B)1.

Front 87

1. In theuncompetitive inhibition,e\~*

Back 87

inhibitor binds only to the complex enzyme-substrate

Front 88

1. Ping-Pongmechanism is:

Back 88

multisubstrate enzyme mechanism

Front 89

1. AlCl3 is:

Back 89

a. Lewis acid;famil~{.)

Front 90

142. Erythrocytes lyses in the solution which is:

Back 90

a. Hypotonic;famil~{.)

Front 91

1. Whatis the wrong assertion? ]],["htt_~[*

Back 91

a. Acetic anhydride is a substitution derivative 99994,"https:V~R*

Front 92

1. Which amino acid, in aqueous solution, will have rotation in globular proteins (?) ? pZ~^*

Back 92

a. ProlineT

Front 93

1. Precursorof AMP and GMP isline<_~[*

Back 93

IMPr{~)j

Front 94

1. Hydrolases need iry": ^~Z*

Back 94

a. Do not need a cofactor T~P*

Front 95

1. Malate-aspartateshuttle is involved in transport of X~\*

Back 95

a. NADH from cytosol to the mitochondria T

Front 96

1. Which pathway is activated by glucagon? ol to the mitoX~\*

Back 96

Lipolysis

Front 97

1. An amino acid NOT involved in urea cycle is o the mitoX~\*

Back 97

Histidine areast-thema~d)

Front 98

1. Theproperties of peptide bond include all, EXCEPT:toX~\*

Back 98

a. It primarily occur in the cisconformationU~Q*

Front 99

1. Anaerobic glycolysis results in: p>Z~^*

Back 99

Decrease of ph

Front 100

1. Which oxygen radical arises from hemoglobin autooxidation? body>

Back 100

a. Superoxide

Front 101

During theanaerobic parts of glycolysis forms:

Back 101

NADHYV

Front 102

In the pentose cycle…. is produced: nt:5~1)y

Back 102

b) NADPH nt:~)

Front 103

For the biosynthesis of amino acids…. is used: > nt:~)

Back 103

FDADH2

Front 104

Among the ketonebodies produced in excess acetyl-CoA that does/do not belong is/are:ST

Back 104

d) pyruvateagment--><~)

Front 105

Which enzyme of the citric acid cycle is localized in inner mitochondrial membrane: ght:0cm;margin-'~#)

Back 105

c) succinate dehydrogenase>&~")

Front 106

The basic structure ofcollagen consists of:--><$~ )

Back 106

triple hel

Front 107

Which of these aminoacids in collagen is most/best represented:

Back 107

glycine

Front 108

For cleavage of peptide bond by proteinases, it does not need/not necessary:

Back 108

d) preliminary protein phosphorylation n-4~0)

Front 109

The amino acid is bound to t-RNA by: n-4~0)

Back 109

ester bond/linkage ily:Calib~)

Front 110

Enzyme thatsynthesizes peptide bonds is:eme-font:4~0)

Back 110

peptidyltransferase ly:Calib~)

Front 111

Enzyme thatsynthesizes peptide bonds is:eme-font:4~0)

Back 111

c) ribozyme)

Front 112

At the termination ofprotein synthesis, the polypeptide chain is transferred to:

Back 112

water

Front 113

Lysosomal proteasesare characterized by:

Back 113

b) acidic pH optimum

Front 114

Proteasomes participate in: EndFrag;~?)

Back 114

c) protein hydrolysisthe polypepJ~N)