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15 Cards in this Set
- Front
- Back
Remicade
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Aka Inflixamib
Humanized Fab on human IgG binds TNF alpha and treats inflammatory diseases like Crohns |
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When is HIV western blot positive?
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p31 or p24
AND gp 160 or gp120 |
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Where does enteropeptidase cleave?
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At lysines preceded by 4 Aspargines
Cleaves trypsinogen to trypsin |
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ALP
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Alkaline phosphatase--
if in blood, can be a marker for rapid bone growth or bone disease (eg, rickets) |
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AST
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Aspartate Aminotranferase
Found in the liver uses pyroxidal phosphate as an enzyme Can detect liver damage (amt of damage directly related to amt of AST in blood) alcoholic hepatitis indicated if AST/ALT > 2 |
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ALT
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Alanine Aminotransferase
another liver enzyme marker tests disease OR if drugs are damaging liver |
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Enzyme markers for MI
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BM form of creatine kinase
Now, myoglobin (appears in 2 hours) and troponin (lasts 2 weeks) |
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Serum amylase levels elevated indicates?
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pancreatic duct obstruction or pancreatic cancer
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Abatacept
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Rheumatoid Arthritis
Binds to CD28 on T cell so it can't be costimulated Decreases production of T cell derived cytokines |
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Rituximab
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For B-cell non-Hodgkins lymphoma, B-cell leukemia
Targets CD20 on B cells |
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Prolastin/Aralast
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for A1-AT deficiency
A1P1 is a proteinase inhibitor |
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Activated C protein
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for sepsis
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Factor VIIa
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Hemophilia
NovoSeven RT- activates X directly, so bypasses problems with VIII and IX |
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TPA
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activates plasminogen
for treatment of MI, stroke, pulmonary embolism works at clot sites- not a whole body anticoagulant |
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Granulocyte CSF
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stimulates bone marrow to produce granulocytes
for chemo induced neutropenia |