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14 Cards in this Set
- Front
- Back
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§Pedigrees:x |
§Pedigrees:Inheritance of Genetic Disease |
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§Afamily tree that |
shows the inheritance of traits |
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§Whyis this important (family tree)? |
§Genetic counselors may use pedigrees to determine if couples will produce healthy children |
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§Diseasescan |
be traced across a pedigree (ex. sickle-cell anemia, hemophilia) |
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§Pedigree: |
inheritance of traits through several generations |
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§Symbols commonly used in pedigrees: |
circle- female square- male off spring in birth order= left to right lines in circles or square= affected individuals half empty and half lined= carriers |
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dad has the gene that causes the disease |
not sex linked, autosomal |
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What is DNA Fingerprinting? |
§Usedin forensic science §Equivalentto a human barcodeorfingerprint§Helpsin the identification of individuals§Paternitytesting§CriminalCases §Notwo individuals are genetically identical(except for MZ twins)§Differencescan be found within DNA |
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Step 1 in DNA Fingerprinting |
§1)DNA isolated from tissue sample §Wherecan we isolate DNA from?Hair, bones, skin, blood (DNA found inall cells |
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Step 2 in DNA Fingerprinting |
§DNA cut into fragments with enzymes §DNA from different individuals produce fragments of different sizes 1,"was_ins |
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Step 3 in DNA Fingerprinting |
§3) Fragments separated on basis of sizeand visualized§Each person’s set of fragments is unique;-J |
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§Small amounts of DNA can be amplifiedusing |
PCR (polymerase chain reaction) |
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§Eachperson |
will have a unique pattern of bands. |
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§Eachband present in a child |
must also be present in one of the child’s parents §Child does not need to have all the bands of parents |
