Bio Exam 2 Immune

Front 1

Hallmark of the immune system?

Back 1

Self vs. Non Self (what's you and what's not you)

Front 2

Three characteristics for an antigen to be immunogenic?

Back 2

Large
Foreign
Complex

Front 3

Cells are ________ of antigens
Antigens are ^ of ________

Back 3

Cells are mosaics of antigens
Antigens are mosaics of epitopes

Front 4

Marker of Identity
Different shapes, sizes, thousands
Expression of genes that helps identify who you are

Back 4

Antigen

Front 5

Why wouldn't an O antigen cause a response?

Back 5

It's not big or complex enough

Front 6

A, B, and O are all _______
But only A and B are _______

Back 6

antigens, immunogens

Front 7

Two divisions of the immune system?

Back 7

Innate and acquired

Innate: No immunological memory
Acquired: Each exposure to immunogen stimulates immunological memory mechanism (BIGGER, QUICKER RESPONSE)

Front 8

What WBCS are associated with each division of the immune system?

Back 8

Innate = Segmented Neutrophils
Acquired = Lymphocytes

Front 9

What are the two divisions of the acquired division of the immune system?

Back 9

Humoral (Antibodies method of attack)
Cell-Mediated (Attach to foreign bodies and attack, perforate cell PERFORIN)

Front 10

What is the method of attack for the innate immune system? WBC?

Back 10

Segmented Neutrophils
Phagocytosis of foreign things
Same level of response, no memory

Front 11

Major Cell of Humoral?
Major Cell of Cell of Cell-Mediated?
Shared Cell?

Back 11

B-Cell (B Lymphocyte)
T Helper
Tc (Cytotoxic)

Front 12

Central Lymphoid organs?
Peripheral Lymphoid organs?

Back 12

Central: Bone marrow and Thymus
Peripheral: Nodes Spleen Tonsils

(Thymus is dorsal to sternum)

Front 13

What occurs in the central lymphoid organs?
Peripheral lymphoid organs?

Back 13

Central = Lymphocytes gain specialty (making antibodies, perforin, etc)

Peripheral = Specialized cells do their work

Front 14

What does the bone marrow produce? what does the thymus produce?

Back 14

Bone marrow = Immunocompetent (committed) B Cells
Progenitor T-Cells

Thymus = Immunocompetent (committed) t cells

Front 15

What are the types of T-cells? What do they use?

Back 15

Cytotoxic (TC)
T-Helper (TH)

Perforin

Front 16

Another name/abbreviation for antibody?

Back 16

Immunoglobulin (ig)

Front 17

What does a committed B-Lymphocyte do that a non-committed can't do?

Back 17

It has immunological memory that recognizes antigens

Front 18

What happens during Clonal Selection?

Back 18

Proliferation (Dividing)
Differentiation (Form more highly specialized cells)

Front 19

Committed lymphocytes differentiate into what two types of cells?

Back 19

Effector cells - Make antibodies, respond to infection. Fight immediately.

Memory cells - High affinity for next exposure. Don't fight the first time but wait for next exposure.

Front 20

What does AIDS/HIV stand for?

Back 20

AIDS = Acquired immune deficiency syndrom
HIV = Human immuno-deficiency virus

Front 21

What portion of the immune system does aids/hiv attack?

Back 21

Acquired

Front 22

Two serological diagnostic tests for HIV?

Back 22

ELISA - Take serum and look for IG against HIV

Western Blot - Looks for protein of HIV

Front 23

Drugs to combat aids?

Back 23

Inhibitor of reverse transcriptase (humans don't have this)
Inhibitor of protease