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53 Cards in this Set

  • Front
  • Back

Genetics

Study of heredity

Gregor Mendel

Discovered basic principles of heredity (pea pods)

Dominant

Uppercase

Recessive

Lowercase

Law of segregation

during the production of gametes the two copies of each hereditary factor segregate so that offspring acquire one factor from each parent

Heterozygous

Ex: Bb

Homozygous

Ex: bb

Alleles

Different forms of a gene (can be dominant or recessive)

Genotype

the genetic constitution of an individual organism

Phenotype

Set of observable characteristics of an individual

Parentals

First set of parents crossed

Principle of dominance

Offspring express dominant trait

Monohybrid cross

Between one trait


Ex: Bb × bb

Dihybrid cross

Between 2 traits


Ex: BbGG × bbGg

Gamete

contains only a single (haploid) set of chromosomes

Incomplete dominance

Offspring have blend of 2 traits


Ex: red × white= pink flower

Co-dominance

Offspring show both parental traits


Ex: red × white = mixed flower

Law of independent assortment

States when gametes r formed, homologous chromosomes must separate

Mitosis

Cell division to make 2 identical cells

Meiosis

Produces 4 gamete cells (sexual)

Somatic cell

any cell of a living organism other than the reproductive cells

Chromosome

carrying genetic information in the form of genes (in nucleus)

Cell plate

(in plant cells) a plate that develops during cytokinesis

Diploid

2 sets of chromosomes (2n)

Haploid

One set of chromosomes (n)

Centrioles

involved in the development of spindle fibers in cell division (animal cells)

Tetrad

four-part structure that forms during prophase I of meiosis (consists of 2 homologous chromosomes, each composed of 2 identical chromatids)

Crossing over

exchange of genes between homologous chromosomes, resulting in a mixture of parental characteristics in offspring

Random assortment

Each sperm and egg will have different chromosome assortments

Homologous chromosomes

The cell has two sets of eachchromosome; one of the pair is derived from the mother and the other from the father

Non-disjunction

failure of homologous chromosomes or sister chromatids to separate properly during cell division

Sister chromatids

"One half" of the duplicated chromosome

Deoxyribose sugar

Found in RNA and DNA

Phosphate

Phosphate backbone forms the frame work for nucleic acids (DNA)

4 nitrogen bases

1. Adenine


2. Guanine


3. Cytosine


4. Thymine

Double helix

The shape DNA makes

Nucleotide

Building blocks of nucleic acids

Complementary base pairing

C + G


A + T

Sex-linked trait

Gene found on the X chromosome not the Y

Polygenic inheritance

one characteristic is controlled by two or more genes

Tay-Sachs disease

fatal genetic disorder that causes progressive damage to the nervous system

PKU (phenylketonuria)

results in decreased metabolism of the amino acid phenylalanine

Albinism

Genetic condition resulting in absence of pigment in the skin, hair and eyes

Sickle-cell anemia

a mutated form of hemoglobin distorts the red blood cells into a crescent shape at low oxygen levels.

Progeria

accelerated aging in children (extremely rare genetic condition)

Huntington's disease

progressive brain disorder that causes uncontrolled movements, emotional problems , and loss of brain cells

FH

is an autosomal dominant genetic disease

Cloning

organisms that are exact genetic copies. Every single bit of their DNA is identical

Karyotype

a test to identify and evaluate the size, shape, and number of chromosomes in a sample of body cells

Pedigree

a diagram that shows the phenotypes of a particular gene or organism and its ancestors from one generation to the next

Mutations

when a DNA gene is damaged or changed in such a way as to alter the genetic message carried by that gene

Genetic counseling

Seeking help from a genetics counselor about possible or current genetic conditions

Pre implantation diagnosis

procedure used prior to implantation to help identify geneticdefects within embryos