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30 Cards in this Set

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Overview

Endocrinology is the study of the structure and function of the endocrine gland and the hormones that they produce

Endocrine gland

Ductless glands manufactures and/or secrete hormones directly into the blood or lymph to elect a response in the body at a target site


(includes pituitary adrenal thyroid gonads and pancreas)

Endocrine gland

Glad the discharge is it secretion into a body cavity or onto the body surface through ducts


( include sweat glands Salvatori gland memory glands and enzyme producing glands)

Hormones

Chemical messenger that is released by a gland travels to the blood or lymph and affects the growth or function of the target site

Steroid hormones

1. diffusers through cell


2. find with the cytoplasmic or nuclear receptor proteins to form a receptor hormone complex


3. receptor hormone complex diffuses through the nuclear membrane and binds to the gene along the DNA


4. either encourages or discourage is protein synthesis


5. production or lack of production of certain proteins causes the intended result of the hormone

Peptide hormone activation

1.binds to a receptor on cell membrane but do not diffuse the cells membrane


2. activate the cascade reaction resulting in the production of second messengers


3. second Masters activate or inhibit enzyme action with an all the cell


4. affects an enzyme cause the intended result of the

Endocrine system vs. nervous system

Nervous tissue in the body can secrete hormones (pituitary and hypothalamus)


Some chemicals released by nervous system can act as a hormone or neurotransmitter (norepinephrine)


Both systems maintain haemostasis through negative feedback


Response in the body may be due to the interactions of both nervous and endocrine systems working together

Homeostasis and negative feedback

homeostasis- regulation of internal environment between narrow limits


(pH temp CO2 H2O go to in glucose)

Homeostasis and negative feedback

Most homeostasis regulation occurs through negative feedback


negative feedback- correction mechanism that re-regulates body back to its homeostatic levels

Melatonin jet leg

Hormone secreted by Pineal gland that regulates circadian rythms


This hormone follows a negative feedback mechanism

Jet leg

Symptom of circadin rhythm that is out of alignment


symptoms- fatigue and sleepiness during day, insomnia at night, irritability and possible indigestion


melatonin can be used to re-regulate this

Positive feedback

Magnified mechanism that usually takes body out of homeostasis


disorders and disease can occur with unregulated positive feedback


as seen with the example regarding melatonin free infrequent homeostatic regulation can occur through the positive feedback


as seen with the example of the birthing hormone oxytocin

The pituitary gland and it’s hormones

Pituitary gland is referred to as the master gland because it releases the tropic hormones that regulate many other in Dockery glance throughout the body

Tropic hormones

Tropic means to influence


a tropic hormone influences other endocrine glands to release hormones

The pituitary gland

Located in the brain


composed of two parts


the posterior pituitary and anterior pituitary

The pituitary gland

Is governed by hormonal and nervous stimulation from the hypothalamus

Posterior pituitary

Receives nervous signals from hypothalamus

Anterior pituitary

Receives hormonal signals from the hypothalamus

Posterior pituitary

Posterior pituitary gland does not produce hormones it stores secreted hormones that are synthesized by the hypothalamus

Neurosecretory cells

Cells of the hypothalamus


Produce hormones hormones travel through these neurons until arriving at the axon terminal located in the posterior pituitary


Receptors direct hormones from accent terminal into pillories found in posterior pituitary


Two types of hormones oxytocin and antidiuretic hormone (OCT or ADH)

Answer to pituitary

No control of hypothalamus however produces own hormones


Neuropsychiatry cells produce tropic hormones released into portal vessel system


delivers Tropic hormone to the anterior pituitary causing release of hormones six main types released from posterior pituitary


growth hormone


thyroid stimulating hormone


ACTH


prolactin


follicle-stimulating hormone


and LH

Growth hormone

Influences the somatocytes

How to identify the growth hormone

Low secretion of HGH in childhood may cause dwarfism


High secretion of hGH in childhood because gigantism


High secretion of HGH after the bone/cartilage growth plates have used because a cromegaly or condition which caused a secondary bone growth


Thyroid gland and it’s hormones

Thyroid gland is a bowl shaped gland located below the larynx in the neck region


Releases hormones that specialize in body metabolism and calcium adoption


Two key hormones released our thyroxin and calcitonin

Thyroxine T4

Produced /release from thyroid gland


stimulates cellular metabolism and all body tissue


stimulates body development through organization of cells into tissues and organs


thyroxin is synthesized using for iodine molecules hence the short form of the hormones name T4


thyroxin does not have a specific target instead it stimulates all body cells to increase cellular respiration

Goitre

Absence of iodine from diet may result in this


enlarge thyroid

Graves’ disease

Autoimmune disorder where the bodies immune system attacks the thyroid and Eye muscles


result in severe form of hyperthyroidism called Graves’ disease

Calcitonin

Produced/released from thyroid


stimulates calcium into bones once blood calcium is in excess of its critical level


reduces blood calcium levels decreases CA2+ reabsorption into the blood from intestines kidneys and bones

Adrenal glands

Two types each position on top of the kidney each is encased in the shell


the inner gland is called the adrenal Medela received your own stimulation


outer is called the adrenal cortex receives hormonal stimulation collectively release hormones that


prepare the body for stress


Aid in regulation of minerals


promote male sexual development

Adrenal Medela

Part of nervous and endocrine system referred to as neuroendocrine structure


due to direct nervous stimulation The adrenal Medela hormonal release is faster but short term to key hormones epinephrin and norepinephrine