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92 Cards in this Set

  • Front
  • Back
Mitosis
a nuclear division mechanism that occurs in somatic cells (body cells) of multi-celled eukaryotes
Meiosis
precedes the formation of gametes or spores and is the basis of sexual reproduction
Sister chromatids
Until the two double-stranded DNA molecules are separated in late nuclear division they are called...
Histones
spools of proteins
Nucelosome
the smallest unit of structural organization in eukaryotic chromosomes
Centromere
when sister chromatids constrict where they attach to one another
Cell cycle
series of events from one cell division to the next
Interphase
three stages during which a cell increases its mass, roughly doubles its numbers of its cytoplasmic components, and duplicates its DNA (G1, S, G2)
Chromosome number
sum of all chromosomes in a cell of a given type
Diploid
two of each type of chromosome
Bipolar spindle
dynamic network of microtubules that grow from opposite poles of the cell
Prophase
the first stage of mitosis; the duplicated chromosomes condense and become threadlike and then rod-shaped; new microtubules also assemble; one of the two centrosomes moves to the opposite pole of the nucleus; bipolar spindle starts
Centrosome
region near the nucleus that will organize microtubules while they are forming
Metaphase
when all of the duplicated chromosomes are aligned midway between the two spindle poles
Anaphase
interval when sister chromatids of each chromosome separate and move toward opposite spindle poles
Telophase
one of each type of chromosome reaches a spindle pole; two nuclei form
Contractile ring
thin band on actin and myosin filaments wrapped around the cell's midsection
Cell plate
fusion of vesicles and their wall-building contents; attaches to the membrane and partitions the cytoplasm
Kinases
class of enzymes that activate other molecules by transferring a phosphate group to them; can activate certain proteins in a cascade of signaling events that stops the cell cycle of induces cell death
Growth factors
activate genes that stimulate cells to grow and divide
Tumor
an abnormal mass neoplasms - abnormal masses of cells that lost control over how they grow and divide
Cancer
abnormally growing and dividing cells of a malignant neoplasm; physically and metabolically disrupt surrounding tissues
Asexual reproduction
all offspring inherit the same number and kinds of genes from a single parent
Genes
sequences of DNA that encode heritable information about traits
Clones
genetically identical copies of the parent
Sexual reproduction
process involving meiosis, formation of mature reproductive cells called gametes, and then fertilization
Allele
each unique molecular form of the same gene
Meiosis
nuclear division process that divides the parental chromosome number in half
Gametes
mature reproductive cells
Zygote
the first cell of a new individual
Homologous chromosomes
same length, shape, and assortment of genes in the chromosomes of a pair
Haploid
half of the parental chromosome number
Crossing over
a process by which a chromosome and its homologous partner exchange corresponding segments
Sporophyte
often a diploid and spores form in part of it
Gameotophyte
multicelled haploid body inside which one or more gametes form
Sperm
type of mature male gamete
Fertilization
fusion of the haploid nuclei of two gametes
Genes
heritable units of information about traits
Diploid
pairs of genes on pairs of homologous chromosomes
Mutation
permanent change in a gene that in the information it carries
Hybrids
cross between two individuals that breed true for different forms of a trait
Homozygous dominant
has pair of dominant alleles (AA)
Heterozygous
pair of nonidentical alleles (Aa)
Homozygous
pair of recessive alleles (aa)
Gene expression
process by which a gene's information is converted to a structural of functional part of a cell
Genotype
particular alleles that an individual carries
Phenotype
refers to an individual's traits
Monohybrid experiments
test for dominant or recessive alleles at one locus
Testcross
method of determining genotype in which an individual of an unknown genotype is crossed with another that is homozygous recessive and the results may show if the individual is heterozygous or homozygous for a dominant trait
Mendel's theory of segregation
diploid cells have pairs of genes, on pairs of homologous chromosome; the two genes of each pair are separated from each other during meiosis, so they end up in different gametes
Dihybrid experiments
test for dominant or recessive alleles at two loci
Mendel's theory of independent assortment
as meiosis ends, genes on pairs of homologous chromosomes have been sorted out for distribution into one gamete or another independently of gene pairs on other chromosomes
Codominance
nonidentical alleles for a gene are both fully expressed; neither is dominant or recessive in heterozygotes
Multiple-allele systems
codominance may occur in which three or more alleles of a gene persist among individuals of a population
Incomplete dominance
one allele of a pair is not fully dominant over its partner so the heterozygote's phenotype is somewhere between the two homozygotes
Epistasis
interactions among products of two or more gene pairs
Pleiotropy
one gene may influence two or more traits
Linkage group
all of the genes on a chromosome
Continuous variation
range of small differences in most traits among natural populations
Polygenic inheritance
the inheritance of multiple genes that affect a trait
Autosomes
chromosomes with the same length, shape, and centromere location
Sex chromosomes
chromosomes with different length which determine an individual's sex
Karyotype
shows whether or not there are extra or missing chromosomes
Duplications
DNA sequences that are repeated two or more times; occur during unequal crossovers at prophase I
Deletion
loss of some portion of a chromosome
Inversion
part of the sequence of DNA within the chromosome becomes oriented in the reverse direction, with no molecular loss
Translocation
if a chromosome breaks, the broken part may get attached to a different chromosome or to a different part of the same one
Nondisjunction
one or more chromosome pairs do not separate during mitosis or meiosis
Aneuploidy
cells have too many or too few copies of a chromosome
Polyploid
cells have three or more of each type of chromosome
Pedigrees
charts of genetic connections
Syndrome
genetic disorder characterized by a specific set of symptoms
Disease
illness caused by infection or environmental factors
Bacteriophage
type of virus that infects bacteria
DNA polymerase
bonds nucleotides together into a new strand according to the order of nucleotides of a template
DNA ligase
enzyme that seals any gaps in the new DNA strands
DNA repair mechanisms
can fix damaged DNA
Transcription
first step in protein synthesis where a sequence of nucleotide bases becomes exposed in an unwound region of a DNA strand; a strand of RNA is synthesized
Messenger RNA (mRNA)
carries protein-building codes
Ribosomal RNA (rRNA)
becomes part of ribosomes, the structures upon which polypeptide chains are assembled
Transfer RNA (tRNA)
delivers amino acids one by one to ribosomes in the order specified by mRNA
RNA polymerase
adds the nucleotides one at a time to the end of a growing transcript
Promoter
nucleotide sequence when RNA polymerase attaches to its binding site in the DNA
Introns
nucleotide sequences that are removed from a new RNA
Exons
sequences that stay in the RNA
Codon
base triplet in mRNA
Genetic code
set of 64 mRNA codons used in protein synthesis
Anticodon
a triplet of nucleotides that base-pairs with a complementary mRNA codon
Translation
process that coverts genetic information encoded in an mRNA transcript into a new polypeptide chain
Base-pair substitution
when wrong nucleotide is paired with an exposed base on a template strand and slips by proofreading and repair enzymes
Insertions or deletions
when one or more base pairs are inserted into DNA or deleted from it
Transposable elements
segments of DNA that can insert themselves anywhere in a chromosome