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18 Cards in this Set
- Front
- Back
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microtuble functions in all cells include being a ________ for organelles and secretory vesicles, helping to __________, and forming the ________ along which________. |
1. highway 2. form the ER 3. mitotic spindle 4. chromosomes move during mitosis |
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in specialized cells microtubles can be found as ______, which ________, or ______ which help the cell ______. |
1. cilia 2. move things over cells 3. flagella 4. move |
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microtubles can help move the placement of _______. they can also ________ |
golgi apparatus transport membrane-bound organelles in cell |
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in the mitotic spindles _____ act as the spindle poles |
centrosomes |
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in cilia, the MTOC acts as _______ |
basal body |
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cilia have functions in both the ______ where it ______ and the ______ where it ______. |
1. throat 2. moves particles 3. oviduct 4. moves eggs |
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How does MTOC function in neurons? |
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microtubules are made of _______, which include _______ subunits. |
1. tubulin dimers 2. alpha and beta subunits |
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both alpha and beta have ______ attached to them |
GTP |
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new dimers add to the _____ end of the protofilaments |
+ end |
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GTP _______ the entire Microtubule. When the cap is lost, _________ happens. This is called ________. |
1.stabilizes 2. rapid shrinking 3. dynamic instability |
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how is a protofilament rescued? |
by adding alpha/beta GTP cap back on |
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what is taxol and how does taxol work? |
taxol is a cancer drug that stabilizes microtubules against depolymerization and therefore prevents mitosis |
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______ are the origins of microtubules, there is a pair of ______ surrounded _________by nucleating sites of _________ that the positive ends grow from. |
centrosomes centrioles pericontriolar material gamma-tubulin ring complexes |
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_________ initiates new microtubules. They _______. |
gamma-TURCs, they "cap" the (-) end. |
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microtubules are ______ in interphase and ______ in mitosis |
long short |
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in mitotic cells, ________ causes shorter microtubules, where in interphase ________. |
tubulin GTPase activity causes catastrophe there is less catastrophe |
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the difference in microtubule polymerization and depolymerization is ________ in interphase and mitotic cells. The rate of catastrophe is ______ in mitotic cells. |
equal 5x greater |
