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10 Cards in this Set

  • Front
  • Back

GPCR binds to _________

Heterotrimeric g proteins, alpha, beta, and gamma

on beta-adrenergic receptor, adrenaline binds to _______ and the g protein binds to ______

charged transmembrane residues


3rd loop and some of c terminus

Gs _________


Gi _________


Gt _________


Golf________


Ggust

Gs stimulates adenylate cyclase


Gi inhibits AC


Gt is for transducin, in the eyes it is the G protein for rhodopsin which is the receptor for light


Golf is for olfactory


Ggust is gustducin for sweet, bitter, umami

olfactory neurons' cilia is unique because it is ______

non-motile

different smells are ________


two examples are _____, which smell like sweaty socks, and ______ which smells like roses

oderants


octanoic acid


octanol

in olfaction, once cAMP has been released by Golf, it opens _________ which causes ______.

a cyclic nucleotide-gated ion channel


this causes an influx of Ca++ which further depolarizes the cell

Gq activates ____________

phospholipase C, which breaks down PIP2 into DAG and IP3

IP3's job is to ________-

bind to a ligand-gated ion channel that lets in Ca++. Calcium activates calmodulin

DAG's job is to ________

bind to protein kinase C

What is the difference between pheremones and Kairomones?

Pheremones signal from one individual of a species to another, where Kairomones signal from one species to a different one and it benefits the receiver of the signal