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42 Cards in this Set
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- Back
- 3rd side (hint)
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fimbrial adhesions, EAST toxin, verotoxins I and II, intimin, heat labile enterotoxin, heat stable enterotoxin, P fimbriae, α and β_hemolysins; all depending on the strain
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Escherichia coli
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watery diarrhea, bloody diarrhea, HUS, colitis, neonatal meningitis, septicemia, UTIs depending on the strain
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no known toxins, fimbriae wrap around bacterial cells which aggregate in the lumen of the digestive system
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EAEC
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enteroadherent E. coli; diarrhea in young children
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Enteroaggregative ST toxin a (heat labile hemolysin); aggregates on mucosal cells
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EaggEC
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enteroaggregative E. coli; non-bloody diarrhea
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Verotoxin I and II, I is an AB toxin produced in iron deficient environments, II is responsible for HUS; both are shiga-like toxins
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EHEC
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enterohemoyltic E. coli (O157:H7); hemorragic diarrhea, colitis, hemolytic uremic syndrome (HUS)
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invades colonic cells and spreads laterally using mechanisms similar to Shigella
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EIEC
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enteroinvasive E. coli, dysentery: watery, pus, mucoidal, bloody stool; high infective dose required
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adheres to intestinal microvilli using intimin; causes lesions on microvilli
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EPEC
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enteropathogenic E. coli; causes severe, persisitent infant diarrhea
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produces heat labile and heat stable toxins; heat labile(similar to cholra) raises cAMP; heat stable raises cGMP
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ETEC
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enterotoxigenic E. coli; causes watery "traveler's diarrhea"; requires high infective dose
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use adhesins (P fimbria) that bind to P antigens on uroepithelial cells; α_hemolysin lyses lymphocytes; β_hemolysin inhibits phagocytosis and chemotaxis of neutrophils
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Uropathogenic E. coli
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causes 90% of UTIs
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capsule
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Klebsiella pneumoniae
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nosocomial lower respiratory infections; UTIs and septicemia in immunocompromised; mucoidal colonies
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capsule
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Klebsiella oxytoca
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nosocomial lower respiratory infections; UTIs and septicemia in immunocompromised; mucoidal colonies
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motile
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Enterobacter
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isolated from wounds, urine, blood, and CSF
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antimicrobial resistant
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Serratia marcescens
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nosocomial outbreaks of UTIs, respiratory tract, and bacteremia
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peritrichous flagella
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Proteus mirablis
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isolated from urine, wounds, ears, and blod
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peritrichous flagella
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Proteus vulgaris
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isolated from urine, wounds, ears, and blod
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not mentioned
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Citrobacter freundii
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diarrhea, nosocomial UTIs, intraabdominal abscesses
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binds to TLR-5 receptor on mucosal cells and is taken up; prevents phagosome-lysosome fusion; type III secretion system
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Salmonella sp.
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fecal-oral ingestion; acute gastroentiritis; food poisoning; enteric fever; non-typhoidal bacteremia; carrier state (in gallbladder perhaps requiring cholecystectomy)
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binds to TLR-5 receptor on mucosal cells and is taken up; prevents phagosome-lysosome fusion; type III secretion system
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Salmonella typhoid
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TYPHOID FEVER; fecal-oral ingestion; acute gastroentiritis; food poisoning; enteric fever; non-typhoidal bacteremia; carrier state (in gallbladder perhaps requiring cholecystectomy); low infectious dose (10 to 20); rose spot rash
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binds to TLR-5 receptor on mucosal cells and is taken up; prevents phagosome-lysosome fusion; type III secretion system
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Salmonella enteritidis
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FOOD POISONING; HIGH INFECTIOUS DOSE; fecal-oral ingestion; acute gastroentiritis; food poisoning; enteric fever; non-typhoidal bacteremia; carrier state (in gallbladder perhaps requiring cholecystectomy)
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Shiga toxin I and II (AB toxin)--STX 1 and 2; inhibits protein synthesis at rRNA; hijacks host cell antigen to spread cell to cell; cytotoxins
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Shigella sp.
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can cause necrosis, enterotoxicity, neurotoxicity; shigellosis; water diarrhea; dysentery; low infectious dose
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type III secretion system
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Yersinia pestis
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causes bubonic and pneumonic plague
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cold growth
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Yersinia enterocolitica
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causes enterocolitis, comes from contaminated food, milk, water, or pets
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watery diarrhea, bloody diarrhea, HUS, colitis, neonatal meningitis, septicemia, UTIs depending on the strain
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Escherichia coli
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G- dry rods, β_hemolytic, lac, indole, MR+; H2S, indole, citrate, urease-
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enteroadherent E. coli; diarrhea in young children
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EAEC
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G- dry rods, β_hemolytic, lac, indole, MR+; H2S, indole, citrate, urease-
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enteroaggregative E. coli; non-bloody diarrhea
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EaggEC
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G- dry rods, β_hemolytic, lac, indole, MR+; H2S, indole, citrate, urease-
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enterohemoyltic E. coli (O157:H7); hemorragic diarrhea, colitis, hemolytic uremic syndrome (HUS)
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EHEC
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G- dry rods, sorbitol-, β_hemolytic, lac, indole, MR+; H2S, indole, citrate, urease-
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enteroinvasive E. coli, dysentery: watery, pus, mucoidal, bloody stool; high infective dose required
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EIEC
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G- dry rods, β_hemolytic, lac, indole, MR+; H2S, indole, citrate, urease-
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enteropathogenic E. coli; causes severe, persisitent infant diarrhea
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EPEC
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G- dry rods, β_hemolytic, lac, indole, MR+; H2S, indole, citrate, urease-
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enterotoxigenic E. coli; causes watery "traveler's diarrhea"; requires high infective dose
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ETEC
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G- dry rods, β_hemolytic, lac, indole, MR+; H2S, indole, citrate, urease-
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causes 90% of UTIs
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Uropathogenic E. coli
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G- dry rods, β_hemolytic, lac, indole, MR+; H2S, indole, citrate, urease-
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nosocomial lower respiratory infections; UTIs and septicemia in immunocompromised; mucoidal colonies
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Klebsiella pneumoniae
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G- rod; indole-; mucoidal; lac+
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nosocomial lower respiratory infections; UTIs and septicemia in immunocompromised; mucoidal colonies
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Klebsiella oxytoca
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G- rod; indole+; mucoidal; lac+
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isolated from wounds, urine, blood, and CSF
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Enterobacter
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G- rod; motile; somewhat mucoidal; citrate+; lac+
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nosocomial outbreaks of UTIs, respiratory tract, and bacteremia
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Serratia marcescens
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G- rod; pink to red pigment on clear agar at room temp; ferments lactose slowly
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isolated from urine, wounds, ears, and blod
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Proteus mirablis
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G- rod; swarming colonies; urease, H2S+; indole, lac-; K/A
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isolated from urine, wounds, ears, and blod
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Proteus vulgaris
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G- rod; swarming colonies; urease, H2S+; indole, lac+; A/A
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diarrhea, nosocomial UTIs, intraabdominal abscesses
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Citrobacter freundii
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G- rod; citrate+; immotile; methyl red +; lac/urease + (slow); H2S+
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fecal-oral ingestion; acute gastroentiritis; food poisoning; enteric fever; non-typhoidal bacteremia; carrier state (in gallbladder perhaps requiring cholecystectomy)
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Salmonella sp.
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G- rod; lac-, H2S+; VP, indole, urease-
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TYPHOID FEVER; fecal-oral ingestion; acute gastroentiritis; food poisoning; enteric fever; non-typhoidal bacteremia; carrier state (in gallbladder perhaps requiring cholecystectomy); low infectious dose (10 to 20); rose spot rash
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Salmonella typhoid
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G- rod; lac-, H2S+; VP, indole, urease-
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FOOD POISONING; HIGH INFECTIOUS DOSE; fecal-oral ingestion; acute gastroentiritis; food poisoning; enteric fever; non-typhoidal bacteremia; carrier state (in gallbladder perhaps requiring cholecystectomy)
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Salmonella enteritidis
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G- rod; lac-, H2S+; VP, indole, urease-
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can cause necrosis, enterotoxicity, neurotoxicity; shigellosis; water diarrhea; dysentery; low infectious dose
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Shigella sp.
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G- rod; 4 O antigen groups (A-D); immotile; lac-
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causes bubonic and pneumonic plague
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Yersinia pestis
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G- bipolar coccobacilli; lac-, motility+, urease-
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causes enterocolitis, comes from contaminated food, milk, water, or pets
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Yersinia enterocolitica
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G- bipolar coccobacilli; lac-, motility+, urease+, CIN agar bullets; incubate at 25C
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