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9 Cards in this Set

  • Front
  • Back
alcohol's real name? abbreviation and chemical formula
Alcohol = ethanol (ETOH)= CH—CH—OH
where is ethanol absorbed and how is it transported?
Ethanol is readily absorbed from gi tract & is
transported unaltered in the bloodstream
what is calorie value of alcohol?
7 kcal/g
what percent of alcohol ingested can be metabolized?
90%
How many grams of ethanol can a person metabolize per hour?
5-7 grams per hour
what are the 2 main enzyme systems for metabolizing ethanol?
1) Alcohol Dehydrogenase (ADH) Pathway

2) Microsomal Ethanol Oxidizing System (MEOS)
1) Alcohol Dehydrogenase (ADH) Pathway
takes place when ETOH in low-moderate concentrations

ADH is in cytoplasm (liver) & requires NAD+ (H acceptor) ADH also found in gastric mucosa (males > females)

first step : oxidizes ETOH to acetaldehyde(CH3-CHO) + NADH, H+

NADH can be oxidized for ATP in electron transport system
other location of ADH
ADH also found in gastric mucosa (males > females)
Acetaldehyde is toxic to cells
Attaches to proteins & alters function & structure
(cirrhosis)

Contributes to “hangover” symptoms

Some ethnicities (Asians) have special forms of ADH that
promote rapid production of acetaldehyde, which makes
the drinker feel sick