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50 Cards in this Set

  • Front
  • Back
Uncomfortale awareness of breathing is called:
Dyspnea
What are the 2 most common causes of chronic dyspnea?
COPD or Heart Failure
The 3 most common causes of acute dyspnea are:
PE, Pneumothorax, or Pneumonia
What is the most common cuase of chronic cough?
Cigarette Smoking
Mechanical or Chemical irritation of the upper or lower respiratory tracts results in what reflex?
Cough
What is the most important step in evaluation of cough?
History and Physical
If cause not apparent from H&P, what is the next step in evaluation of cough?
CXR (Chest X-ray)
Cough suppression should only be used to treat what?
Side Effects (sleep disturbance)
What central antitussives are usually used to treat side effects of cough?
Dextromethorphan and Codeine (Narcotic)
How do central antitussives work?
Increase threshold of central cough center
How do peripheral antitussives work?
Anesthetize peripheral irritant receptors
What are common peripheral antitussives used to treat the side effects of cough?
Benzonatate, Phenol, Menthol
Excess tracheobronchial mucus production causing productiive cough for at least 3 months a year for 2 years is the definition of what?
Chronic Bronchitis
Abnormal dilatation of terminal airspaces with destruction of alveolar septa si the definition of what?
Emphysema
How is emphysema diagnosed?
Pathologically
How is Chronic Bronchitis diagnosed?
Clinically
Centrilobular emphysema is associated with what?
Cigarette Smoking (C's stick together)
Panacinar emphysema is associated with what?
Alpha 1 Antitrypsin Deficiency (Both have lots of A's)
The hallmark of chronic bronchitis is:
Cough with Sputum Production
Blue Bloaters describes:
Chronic Bronchitis
Pink Puffers describes:
Emphysema
Dyspnea initially with rest progressing to dypnea with rest is characteristic of:
Emphysema
What has been shown to be a predictor of mortality in patients with COPD?
FEV1
Normal PaCO2 and slightly lowered PaO2 indicates what?
Emphysema
Elevated PaCO2 and depressed PaO2 indicates what?
Chronic Bronchitis
Destruction of terminal airspaces is characteristic of what?
Emphysema
What is the most important step in management of both Emphysema and Chronic Bronchitis?
Smoking Cessation
What is the only pharmacologic therapy that has been proven to improve survival and quality of life in COPD?
Oxygen Therapy
Decreased FVC, FEV1, FEV1/FVC, DLCO, Increased TLC and RV indicate what?
Emphysema
Decreased FVC, FEV1, FEV1/FVC, Normal TLC and DLCO and Increased RV indicate what?
Chronic Bronchitis
Decreased FVC, FEV1, FEV1/FVC, Normal TLC, Increased RV and DLCO indicate what?
Asthma
Decreased FVC, FEV1, normal to increased FEV1/FVC indiate what?
Restrictive Disease
An episodic abnormally heightened responsiveness of the tracheobronchial tree leading to expiratory airflow obstruction is:
Asthma
What is a key pathophysiologic feature in asthma?
Chronic Airway Inflammation
Acute attacks of asthma are often triggered by stimlui that produce bronchoconstriction in the setting of what?
Chronic Airway Inflammation
What are the most potent and widely used bronchodilators?
Beta Agonists
What is the mechanism of action of Montelukast and Zafirlukast?
Leukotriene receptor antagonist
What is the mechanism of action of Zileuton?
Leukotriene synthesis inhibition
This drug is a moderate bronchodilator and may improve respiratory muscle function and increase respiratory drive:
Theophylline (and methylxanthines)
What are the most potent anti-inflammatory agents available?
Corticosteroids
What si the first choice bronchodilator in patients with COPD?
Ipratropium Bromide (Bronchodilation through vagal stimulation of the airways)
What is the classifcation of a patient who has brief exacerbations and symptoms of asthma 2 or less times per week and nighttime symptoms less than twice a month?
Mild Intermittent Asthma (No daily medication)
What is the treatment for mild intermittent asthma?
Short acting Beta agonist PRN
What is the classification of a patient who has exacerbations affecting his activity more than twice a week but less than once a day with nighttime symptoms more than twice a month?
Mild Persistent Asthma
What is the treatment for Mild persistent Asthma?
Daily corticosteroids (or cromolyn or nedocromil) and short acting beta agonists PRN
What is the classification of a patient who has exacerbations affecting his activity every day and requires daily short acting beta agonists with nighttime symptoms more than once a week?
Moderate Persistent Asthma
What is the treatment for Moderate Persistent Asthma?
Daily inhaled corticosteroids or long acting bronchodilator and short acting beta agonists PRN
What is the classification of a patient who has continual asthma symtpoms that limit physical activity and frequent exacerbations with frequent nighttime symptoms?
Severe Persistent Asthma
What is the treatment for Severe Persistent Asthma?
Daily inhaled corticosteroid and long acting bronchodilators and oral corticosteroid
The constellation of stais, alteration in blood vessels and hypercoagulability is known as:
Virchow's Triad