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50 Cards in this Set
- Front
- Back
Uncomfortale awareness of breathing is called:
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Dyspnea
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What are the 2 most common causes of chronic dyspnea?
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COPD or Heart Failure
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The 3 most common causes of acute dyspnea are:
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PE, Pneumothorax, or Pneumonia
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What is the most common cuase of chronic cough?
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Cigarette Smoking
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Mechanical or Chemical irritation of the upper or lower respiratory tracts results in what reflex?
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Cough
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What is the most important step in evaluation of cough?
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History and Physical
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If cause not apparent from H&P, what is the next step in evaluation of cough?
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CXR (Chest X-ray)
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Cough suppression should only be used to treat what?
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Side Effects (sleep disturbance)
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What central antitussives are usually used to treat side effects of cough?
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Dextromethorphan and Codeine (Narcotic)
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How do central antitussives work?
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Increase threshold of central cough center
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How do peripheral antitussives work?
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Anesthetize peripheral irritant receptors
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What are common peripheral antitussives used to treat the side effects of cough?
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Benzonatate, Phenol, Menthol
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Excess tracheobronchial mucus production causing productiive cough for at least 3 months a year for 2 years is the definition of what?
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Chronic Bronchitis
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Abnormal dilatation of terminal airspaces with destruction of alveolar septa si the definition of what?
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Emphysema
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How is emphysema diagnosed?
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Pathologically
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How is Chronic Bronchitis diagnosed?
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Clinically
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Centrilobular emphysema is associated with what?
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Cigarette Smoking (C's stick together)
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Panacinar emphysema is associated with what?
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Alpha 1 Antitrypsin Deficiency (Both have lots of A's)
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The hallmark of chronic bronchitis is:
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Cough with Sputum Production
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Blue Bloaters describes:
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Chronic Bronchitis
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Pink Puffers describes:
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Emphysema
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Dyspnea initially with rest progressing to dypnea with rest is characteristic of:
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Emphysema
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What has been shown to be a predictor of mortality in patients with COPD?
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FEV1
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Normal PaCO2 and slightly lowered PaO2 indicates what?
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Emphysema
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Elevated PaCO2 and depressed PaO2 indicates what?
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Chronic Bronchitis
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Destruction of terminal airspaces is characteristic of what?
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Emphysema
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What is the most important step in management of both Emphysema and Chronic Bronchitis?
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Smoking Cessation
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What is the only pharmacologic therapy that has been proven to improve survival and quality of life in COPD?
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Oxygen Therapy
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Decreased FVC, FEV1, FEV1/FVC, DLCO, Increased TLC and RV indicate what?
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Emphysema
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Decreased FVC, FEV1, FEV1/FVC, Normal TLC and DLCO and Increased RV indicate what?
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Chronic Bronchitis
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Decreased FVC, FEV1, FEV1/FVC, Normal TLC, Increased RV and DLCO indicate what?
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Asthma
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Decreased FVC, FEV1, normal to increased FEV1/FVC indiate what?
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Restrictive Disease
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An episodic abnormally heightened responsiveness of the tracheobronchial tree leading to expiratory airflow obstruction is:
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Asthma
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What is a key pathophysiologic feature in asthma?
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Chronic Airway Inflammation
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Acute attacks of asthma are often triggered by stimlui that produce bronchoconstriction in the setting of what?
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Chronic Airway Inflammation
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What are the most potent and widely used bronchodilators?
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Beta Agonists
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What is the mechanism of action of Montelukast and Zafirlukast?
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Leukotriene receptor antagonist
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What is the mechanism of action of Zileuton?
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Leukotriene synthesis inhibition
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This drug is a moderate bronchodilator and may improve respiratory muscle function and increase respiratory drive:
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Theophylline (and methylxanthines)
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What are the most potent anti-inflammatory agents available?
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Corticosteroids
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What si the first choice bronchodilator in patients with COPD?
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Ipratropium Bromide (Bronchodilation through vagal stimulation of the airways)
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What is the classifcation of a patient who has brief exacerbations and symptoms of asthma 2 or less times per week and nighttime symptoms less than twice a month?
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Mild Intermittent Asthma (No daily medication)
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What is the treatment for mild intermittent asthma?
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Short acting Beta agonist PRN
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What is the classification of a patient who has exacerbations affecting his activity more than twice a week but less than once a day with nighttime symptoms more than twice a month?
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Mild Persistent Asthma
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What is the treatment for Mild persistent Asthma?
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Daily corticosteroids (or cromolyn or nedocromil) and short acting beta agonists PRN
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What is the classification of a patient who has exacerbations affecting his activity every day and requires daily short acting beta agonists with nighttime symptoms more than once a week?
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Moderate Persistent Asthma
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What is the treatment for Moderate Persistent Asthma?
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Daily inhaled corticosteroids or long acting bronchodilator and short acting beta agonists PRN
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What is the classification of a patient who has continual asthma symtpoms that limit physical activity and frequent exacerbations with frequent nighttime symptoms?
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Severe Persistent Asthma
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What is the treatment for Severe Persistent Asthma?
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Daily inhaled corticosteroid and long acting bronchodilators and oral corticosteroid
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The constellation of stais, alteration in blood vessels and hypercoagulability is known as:
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Virchow's Triad
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