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42 Cards in this Set

  • Front
  • Back

Meiosis

Formation of gametes. Maintains chromosome number from generation to generation because it reduces the number to one copy of each chromosome (23 total) in each sperm and each egg so that at fertilization there are 46.

Spermatogenesis

The process of taking an immature spermatagonia through two mitotic divisions and reducing chromosome number by half. Results in 4 spermatids connected by cytoplasm.

Spermiogenesis

Final maturation process of spermatids, shedding cytoplasm and forming flagella and acrosome.

Acrosome

Head piece of sperm containing hydrolytic enzymes needed to penetrate the egg.

Capacitation

Softening of the head of the sperm (the acrosome), releasing hydrolytic enzymes allowing the sperm to penetrate the egg.

Hormones involved in sperm development

Hypothalamus releases gonadotropin releasing hormone (GnRH) which stimulates anterior pituitary to release LH and FSH. Leutinizing hormone (LH) released by anterior pituitary stimulates interstitial cells in testes to secrete testosterone. Follicle stimulating hormone (FSH) causes maturation of spermatagonia. Testosterone is important in sperm production and secondary sex characteristics.

Where is sperm stored?

Epididymis

Pathway from testicles to urethra

Testes --> efferent ductules --> epididymis --> vas deferens --> ejaculatory duct --> urethra

Oogenesis

While spermatogenesis results in 4 sperm cells, oogenesis results in only one egg. Process of egg development. Meiosis II only occurs if fertilization occurs.

Hormones involved with ovum development

Same as for sperm development, but LH stimulates development of estrogen and progesterone, and FSH stimulates development of oocyte.

HcG

Produced by embryo. Maintains corpus luteum beyond the normal ten days (for up to 3 months) until the placenta is formed.

Mechanisms for maintaining the lower temperature in scrotum

1. Dartos muscle


2. Cremaster muscle


3. Pampiniform plexus

Ovarian ligament

Connects the ovary to the uterus.

Endometrium

Stratum functionalis is shed during menstruation.



Stratum basalis builds up stratum functionalis.


Glands producing secretions for semen

60% from seminal vesicles, 30% prostate gland (sperm activator), 10% bulbourethral glands

Ovulation

On Day 14 of monthly cycle, an LH surge from the anterior pituitary causes the egg to be released (ovulation). Mittelschmerz is a twinge of pain sometimes felt at ovulation. 1 to 2% of ovulation result in an egg being released from both ovaries (which can lead to fraternal twins).

Menstrual cycle

Monthly cycle associated with the maturation of an egg.



Follicular phase: (Days 1-14)


Luteal phase: (Days 14-28)


Ovulation on day 14.

Role of corpus luteum

Secrete progesterone and estrogen to maintain stratum functionalis. If conception occurs, HcG released by the fetus helps maintain the corpus lutein until a placenta is formed. If it does not, the corpus luteum breaks down after about 10 days, leaving only a scar known as the corpus albicans.

Location of fertilization

Distal end of fallopian tube

Function of GnRH

Released from hypothalamus, stimulates anterior pituitary to release FSH and LH.

Stages of labor

Dilation stage


Expulsion stage (delivery of baby)


Placental phase (delivery of placenta)

Major cause of testicular cancer

Cryptorchidism (undescended testicles)

Prolactin

Stimulates milk production

Progesterone's job is to ______________ if pregnancy occurs.

Maintain the uterine lining

Prostate cancer

Second most common cancer in men. Easily treated if it's encapsulated, so early detection is key.

Apgar score

Scale rating how healthy the baby is on birth. 0 to 2 points each for heart rate, respiration, color, muscle tone, reflexes.

Blocks to polyspermy

1. Membrane depolarization


2. Zonal inhibiting proteins (ZIPs)



Polyspermy results in a non-viable zygote.

Embryonic development stages

Zygote (fertilized egg) --> Cleavage (rapid division of cells) --> morula (3 day old embryo - 16 or more cells --> Blastocyst --> implantation

Primary germ layers

Ectoderm (forms nervous system and skin), endoderm (forms epithelial linings of digestive, respiratory, and urigenital systems), mesoderm (forms all other tissues)

Gastrulation

Formation of germ layers. Sets the stage for organogenesis. By the 8th week of pregnancy all organ systems are recognizable.

Amnion (upper part)

Epiblast cells transform into a transparent membranous sac. This sac will eventually fill with amniotic fluid and will completely encase the embryo.

Ectopic pregnancy

Development of embryo outside uterine cavity.

Yolk sac (lower part)

Hypoblast cells that form a sac on the central surface of the embryo.

At what point do the cells become an embryo?

At completion of embryogenesis (about 16 days) when germ layers are formed.

Purpose of uterus

Receive, retain and nourish a developing embryo.

Purpose of inner cell mass?

That is the embryo

Embryonic membranes

1. Amnion - from epiblast cells, accumulates amniotic fluid (about 1 L by the time the baby is born).


2. Yolk sac - bottom part, forms part of digestive tube along with the endoderm.


3. Allantois - spot that goes into umbilicus


4. Chorion - trophoblasts. The baby's contribution to the placenta.

What has happened by end of first trimester?

Bones are ossified, limbs are formed, heart is beating.

Teratogens

Anything that can cause birth defects

Problems affecting premature infants

Lack of surfactant on lungs, liver not being fully functional

Aneuploidy

Presence of an abnormal number of chromosomes in a cell

When does implantation occur?

Between 6 and 14 days after ovulation.