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174 Cards in this Set
- Front
- Back
Largest most numerous neuroglia |
Astrocytes |
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Have many k+ channels to maintain proper balance of K+ for AP generation |
Astrocytes |
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Flat cells that give structural support and material exchange to cell bodies of the PNS nerve cells (neurons) |
Statelite Cells |
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Matter that contains Neural cell bodies |
Grey Matter |
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Tracts of myelinated axons |
White Matter |
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_____ helps prevent Na+ leakage into extracellular fluid (ECF) |
Myelin |
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In CNS an _____ myelinates parts of several axon |
Oligodendrocytes |
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known as glial cells: connective tissues that supports, nourishes, protects, insulates and organizes neurons. |
Neuroglia |
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4 Neuroglia in the Central Nervous System (CNS) |
Astrocytes, Microglia, Ependymal cells, Oligodendrocytes |
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Small, ovoid cells with spiny processes |
Microglia |
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Lines the cavities of thebrain and spinal cord with cerebrospinal fluid. The cilia help to circulate the cerebrospinal fluid to protect the CNS |
Ependymal |
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They are flat extensions around nerve fibers making a fatty insulation called myelin sheaths |
Oligodendrocytes |
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Subarachnoid space b/t Pia Mater and Arachnoid Matter |
Cerebral spinal fluid (CSF) |
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Networks of capillaries that serve as site of CSF production |
Choroid plexus |
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Produce cerebral spinal fluid (CSF) from arterial blood; line the ventricles. |
Epindymal cells |
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Phagocytosize microbes and damaged nervous tissue |
Microglia |
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produces a myelin sheath around axons of neurons of the CNS |
Oligodendrocytes |
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What are tow kinds of Neuroglia in the PNS |
Satelite cells and Schwann cells |
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surround neuron cell bodies in ganglia; protects and regulates nutrients for cell bodies in ganglia |
Satelite Cells |
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supporting cells of the peripheral nervous system responsible for the formation of myelin |
Schwann cells |
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Cell that carries messages through out the nervous system |
Neurons |
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consists of the brain and spinal cord, connected by efferent neurons |
Central Nervous System (CNS) |
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broken into two divisions the afferent and efferent divisions (somatic and autonomic) |
PNS |
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Nerve fibers from CNS to skeletal muscle cells = motor neuron |
Somatic Nervous system |
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Voluntary control single neuron between CNS and skeletal muscle fibers are heavily myelinated stimulation always lead to excitation of muscle ACH released. |
Somatic Nervous System |
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System of motor neurons that supply (and either excite or inhibit) cardiac muscle, glands, smooth muscle, skin pupils of eye, walls and sphincter of gut, gall bladder, urinary bladder. |
Autonomic Nervous System |
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regulates visceral functions. can change viseral functions rapidly and intensly involved in maintenance of homeostasis functions independently, involuntarily and continuously without conscious effort. Divided into the sympathetic and parasympathetic nervous systems. |
Autonomic Nervous System |
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cell body in brain or spinal cord, releases ACh to ganglia, outside of CNS where the pre and post ganglionic neurons meet to postganglionic neurons, sends axons to effector organs |
Preganglionic Neuron |
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Aid the BBB by wrapping ____ processes around capillaries |
Astrocyte |
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a example of ____ is, neurotransmitter binds to recepters in post synaptic neurons plasma membrane causes a depolorization (Na+ channels open, inflow of Na+) OR hyperolorization (K= channels open and outflow of K+) |
signal transmitted by a chemical synapse |
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An example of ____ is, raises in CA+2 causes neurotransmitter release across the cell. |
signal transmitted by a chemical synapse |
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An expample of ____ is, Depolorization opens voltage gated CA=2 channels at synaptic end bulb and Ca+2 diffuses into end bulb |
signal transmitted by a chemical synapse |
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AP arrives at synaptic end bulb of presynaptic axon is an example of____ |
signal transmitted by a chemical synapse |
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vesicle formed around a particle absorbed by phagocytosis formed by the fusion of the cell membrane around the particle. |
Phagosome |
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Coating of bacteria, viruses or dead fragments w/ Ab that complement phagocyte receptors to enhance the import into the phagocyte |
Opsonization |
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cell that can digest microbes and other foreign particles |
Phagocyte |
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acts as a sponge to soak up extra neuortransmitters |
Astrocytes |
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____ in the frontal cortex and hippocampus store and release glycogen as a resevoir of glucose |
Astrocytes |
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have many neurotransmitters for their uptake and release |
Astrocytes |
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Place for exchagne of wastes b/t blood and nervous tissue |
Cerebrospinal fluid (CSF) |
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What prevents Na+ leakage in the extracellular fluid? |
Myelin |
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Take part in axon regeneration following injury in PNS |
Schwann cells |
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3 Layers of meninges, in order |
Dura mater Arachnoid mater Pia mater |
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Dura mater |
(hard mother) outer most and thickest, unstretchable, leathery. Double layered membrane |
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Arachnoid mater |
(spider mother) Soft and spongy. space between arachnoid and pia contains CSF subarachnoid space (large space) contains the major arteries that supply the brain |
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Pia matter |
highly vascular. loose connective tissue contains the smaller surface VB of the brain and spinal cord. |
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meningitis |
inflammation of meninges, may be caused by viruses, bacteria, fungi, parasites or toxins |
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autoimmune disorder, symptoms include" tingling and muscle weakness, fatigue, incoordination of vision, bladder or bowl problems |
Multiple sclerosis |
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2 Neuroglia in the Peripheral Nervous System (PNS) |
Statelite Cells and Schwann Cells |
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Neuroglia of the CNS that filter blood |
Epindymal Cells |
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Menengie that has thicker blood vessels; against the scull AKA Tough mother |
Dura moter |
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contains the dural sinuses |
Dura moter |
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Closest to the brain; impermiable to CSF AKA Soft Mother |
Pia Moter |
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inflamation of menengies |
Meningitis |
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space between pia and arachnoid moter is a space that holds CSF |
Subarachnoid moter |
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Aid in diffusion of glucose; They line or cover teh cell bodies in PNS |
Satelite Cells |
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Myelinates cells in the CNS |
Oligodendrocytes |
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Myelinates cells in the PNS |
Schwann Cells |
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Brings cations in..... |
depolorization |
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outer layer of the wrapping of the Schwann Cells around the axons of the PNS |
Neurolemma |
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Do not possess neurolemma |
Olegodendrocytes |
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Spaces between the wrapping of Schwann cells where there is no myelinization |
Nodes of Ranvier |
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What allows for regeneration of the axons associated with PNS? |
Neurolemma |
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When you suffer damage to PNS due to a burn, drug use, fall or accident its the ___ in the ___ cells that allow you to regenerate those axons |
Neurolemma; Schwann Cells |
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Regeneration is common in ___ because of ___ |
PNS; Neurolemma |
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Why is cell damage regeneration absent in CNS? |
CNS has dendrocytes which lack neurolemma |
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Astrocytes are found in CNS OR PNS? |
Central Nervous System (CNS) |
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Microglia are found in CNS or PNS? |
Central Nervous System (CNS) |
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Ependymal Cells are found in CNS or PNS? |
Central Nervous System (CNS) |
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Olegodendrocytes are found in CNS or PNS |
Central Nervous System (CNS) |
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Satelite Cells are found in CNS or PNS? |
Peripheral Nervous System (PNS) |
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Schwann Cells are found in CNS or PNS? |
Peripheral Nervous System (PNS) |
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Key component of your immune system associated with nervous system. |
Microglia |
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Key feature of Microglia is? |
Specificity |
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Process where phagocytes are attracted to the area of invasion by chemical products of the microorganism, phospholipids, released by injured mammalian cells, or by component of the component system. |
Phagocytosis |
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C3b component of compement coats bacteria of other particles then binds C3b receptors to the phagocyte this coating process to enhance phagocytosis is called |
Opsonization |
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vacuole that the microorganism is then engulfed by the phagocyte is known as |
phagosome |
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A ____ axon can sent AP more quickly. |
Myelinated |
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Oligodendrocytes in the CNS when the myelin degeneration occurs, it can be regenerated, however over time, it the oligodendrocytes themselves are attached making it harder for them to regenerate the myelin. This degeneration is an attach by the immune system, a disorder called |
Multiple sclerosis (MS) |
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MS is ____ meaning its nerve degenerations gets worse over time. |
Neurodegenerative |
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Electric synapses are common among ___ muscles cells while neuronal chemical neurotransmitters are released from ___. |
Smooth, synaptic end bulbs |
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Satellite cells are neuroglia of the ___ that play a role in the ___. *formation of the BBB *structural support *Myelination |
PNS, Structural support |
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Astrocytes are neuroglia of the ___ that play a role in ___. *formation of the BBB *structural support *myelination of axons |
CNS, formation of the blood-brain barrier |
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Schwann cells are neuroglia of the ___ that play a role in ___. *formation of the BBB *structural support *myelination of axons |
PNS, myelination of axons |
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Ependymal cells are neuroglia of the ___ that play a role in ___. *phagocytosis of microbes *structural support *production of cerebral spinal fluid
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CNS, production of cerebral spinal fluid |
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Microglia are neuroglia of the ___ that play a role in ___. *phagocytosis of microbes *structural support *production of cerebral spinal fluid |
CNS, phagocytosis of microbes |
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Oligodendrocytes are neuroglia of the ___ that play a role in ___. *formation of the BBB *structural support *myelination of axons |
CNS, myelination of axons |
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Multiple sclerosis is a disease in which lesions of ___ matter form as a result of damage to the ___. |
white, oligodendrocytes |
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During phagocytosis, a microbe is engulfed by a ___ vesicle that fuses with a ___ which releases digestive enzymes for destruction of the microbe. |
phagocyte, lysosome OR phagosome, lysosome |
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The ___ mater contains large blood vessels that split into capillaries in the ___ mater. |
Dura, pia |
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Lower half of the brainstem, continuous with spinal cord |
Medulla Oblongata (medulla) |
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Connects spinal cord and brain; left and right hemispheres |
Pons |
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Region of brain that connects cerebrum w/ spinal cord and consists of the midbrain, medulla oblongata, pons and reticular activating system (RAS) |
Brainstem |
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Reflex centers for visual, auditory and startle reflex |
Midbrain |
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Provides sensory and motor relays to the face and neck via the cranial nerves |
Brainstem |
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Nuclei of vagus nerve for heart rate and breathing rate |
Medulla oblongata (medulla) |
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Nuclei for swallowing: controls muscles of pharynx and larynx |
Medulla oblongata (medulla) |
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With the medulla, controls inhalation and exhalation |
Pons |
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Sensory impulses for teeth, tongue and part of the face- sends motor impulses to jaw |
Pons |
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Contains cardiac (regulates heart rate) respiratory (breathing rate) vomiting and vasomotor (BP, by constriction or dilation of blood vessels)centers |
Medulla oblongata (medulla) |
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Motor impulses to eye and muscles of facial expression |
Pons |
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Cluster of connected nuclei that maintains wakefulness and sleep-wake cycle |
Reticular activating system |
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Reticular activating system found in |
Midbrain |
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Inactivation of the RAS produces sleep |
Midbrain |
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Damage to RAS results in |
Coma |
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a state of unconsciousness from which individuals can not be aroused |
coma |
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In a coma ___ receives sensory input from eyes, ears, somatosensory (touch) but not smell |
Reticular activating system (RAS) |
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____ is where neurons release the neurotransmitter dopamine to regulate involuntary muscle activities; loss of these neurons is associated with Parkinsons in the ___. |
Substantia Nigra, Midbrain |
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Area associated with symptons of parkinsons |
Midbrain |
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what is treated with dopaminergic drugs to slow severity of symptoms in the ___. |
Parkinsons, Midbrain |
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2nd largest part of the brain and is separated from cerebrum by transverse fissure |
Cerebellum |
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___ compares intended movements w what is happening with skeletal muscles to regulate posture, equilibrium and balance |
Cerebellum |
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damage causes disorders of fine movement, equilibrium, posture and motor |
Cerebellar |
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relay station for pain, temp, touch and pressure relayed to cerebral cortex via thalamus. |
Diencephalon |
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Thalamus is found in the |
Diencephalon |
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found in the ___includes the ___ gland which secretes more melatonin in dark than light to promote sleep and help regulate circdian rhythms |
Epithalamus, Diencephalon, pineal |
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Hormones of the ___ are the master switch of the pituitary gland; receives inputs from thalamus, limbic system, cerebral cortex |
Hypothalamus, |
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What hormones of the hypothalamus are released (2) |
Corticotropin-releasing hormone (CRH) and Adrenal corticotrophic hormone (ACTH) |
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Hypothalamus releases CRH to the anteriror pituitary that releases ACTH into the blood and into the adrenal medulla to release |
corticosteroids |
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Axons extend from nuclei in the ___ to sympathetic and parasympathetic nuclei in the brain stem and spinal cord to regulate HR, movement of food in GI track, and contraction of the urinary bladder. |
Hypothalamus |
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Controls the body temp by monitoring blood temp |
hypothalamus |
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Tells you that your full and where its found |
satiety center, hypothalamus |
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tells you that your hungry and where its found |
Hunger center, hypothalamus |
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when these cells experiance high osmotic pressure due to extracellular fluid and causes sensation of.... and where found at |
Thirst center , hypothalamus |
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wake up and sleep cycle know as |
circadian clock |
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Function of the ___ controls circadian clock (wake up and sleep cycle) by receiving input from the retina and transferring info to the reticular formation and pineal gland |
hypothalamus |
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GnRH, hormone of the hypothalamus |
Gonadotropin-releasing hormone (hormone of the hypothalamus) |
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Gonadotropin-releasing hormone released to the anterior pituitary to the follicle stimulating hormone (FSH) and luteinizing hormone (LH) both released by the __ __ gland |
anterior pituitary |
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Gonadotropin hormones that regulate ovaries and testes (2) |
Follicle stimulating hormone (FSH) Luteinizing hormone (LH) (hormone of the hypothalamus) |
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contraction of smooth muscles of uterine wall during delivery, mother-child bond, release of brest milk, pleasure of sexual intercourse |
Oxytocin (hormone of the hypothalamus) |
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regulate metabolism, energy, growth and development |
Thyrotropin releasing hormone (TRH) (hormone of the hypothalamus) |
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inhibits release of growth hormone (GH) by the anterior pituitary |
Growth hormone-inhibiting hormone (GHIH) (hormone of the hypothalamus) |
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___ aids healthy bone, muscle mass, fat distribution |
Growth Hormone (GH) (hormone of the hypothalamus) |
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Roles in the consolidation of information from short-term memory to long-term memory, declarative/explicit memory and spatial navigation, not procedural memory |
The hippocampus |
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has higher numbers of glucocorticoid receptors and is more vulnerable to long-term stress than most other brain areas |
the hippocampus |
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___ affect the hippocampus in 3 ways
1. Reduce ability for neurons to transmit AP 2. Inhibit neurogenesis (birth of new neurons) 3. Atrophy of dendrites |
Glucocorticoids
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seen w PTSD, sushings syndrome (higher levels of cortisol) and severe depression (reversible w anti-depressants) |
the hippocamus |
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what shrinks from Alzheimer's Disease |
Hippocampus |
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cluster of neuron cell bodies involved in fear, aggressive behavior, male sex motivation |
Amygdala |
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people with PTSD have a larger ___ w greater glucose metabolism |
Amygdala |
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higher connectivity w hippocampus explains link bt fear and memory |
Amygdala |
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protist parasite that cycles bt cats and secondary hosts |
Toxoplasma gondii |
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parasites can alter host behavior to increase parasite transmission efficiency is |
behavioral manipulation hypothesis |
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rats infected w ___ are still afraid of light, open spaces and classically conditioned to fear new things |
T. gondii (toxoplasma gondii) |
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cysts in the amygdala |
Toxoplasma gondii (t. gondii) |
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Has a gene from tyrosine hydroxylase, and enzyme that converts tyrosine into dopamine, a neurotransmitter associated w pleasure |
Toxoplasma gondii (t.gondii) |
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specifically block rats' innate predator aversion associated with cat urine and associates sexual pleasure in rates w cat urine |
Toxoplasma gondii (t.gondii) |
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Electric synapses are common between ___ muscle cells and pass through ___ from one cell to the next. *skeletal, gap junction *cardiac, synaptic cleft *smooth, gap junction |
smooth, gap junction |
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Action potentials travel more slowly through ___ synapses. In a chemical synapse, a ___ opens calcium channels at the synaptic end bulb. *chemical, hyperpolarization *electric, depolarization *electric hyperpolarization |
electric, depolarization |
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Astrocytes are neuroglia of the ___ that play a role in ___. *CNS proper levels of neurotransmitters *CNS, phagocytosis of microbes *CNS, structural support |
CNS, proper levels of neurotransmitters |
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Neurotransmitter binds to receptors of the ___ neurons plasma membrane and may cause a ___ as a result of the ___ of sodium cation. *postsynaptic, depolarization, outflow *Presynaptic, hyperpolarization, inflow *postsynaptic, depolarization, inflow |
postsynaptic depolarization, inflow |
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Astrocytes are neuroglia of the ___ that play a role in ___. *CNS, proper levels of potassium in/out of cell *CNS, myelination of axon *CNS, structural support |
CNS proper levels of potassium in and out of the cell |
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Satellite cells are neuroglia of the ___ that play a role in ___. *PNS, formation of BBB *PNS, myelination *PNS, structural support |
PNS, structural support |
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___ are neuroglia with neurolemma that take part in axon regeneration in the ___. *Schwann cells, CNS *Schwann cells, PNS *Microglia, CNS |
Schwann cells, PNS |
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Oligodendrocytes are neuroglia that play a role in ___. *Phagocytosis of microbes, myelination *Myelination, axon regeneration *Axonal regeneration, myelination |
myelination, axon regeneration |
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the medulla is part of the ___ and has nuclei involved in ___. *Brain stem, fear rate *Diencephalon, spatial navigation *Brain stem, heart rate |
Brain stem, heart rate |
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the medulla is part of the ___ and has nuclei involved in ___. *Brain stem, swallowing *Brain stem, spatial navigation *Brain stem, explicit memory |
Brain stem, swallowing |
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the reticular activation system (RAS) is part of the ___; damage to the RAS can result in ___. *Cerebrum, coma *Midbrain, Coma *Cerebrum, Parkinsons disease |
Midbrain, coma |
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the substantia nigra is part of the ___; neuron loss in the substantia nigra is associated with ___. *Cerebrum Parkinsons *Midbrain, Alzheimers *Midbrain, Parkinsons |
Midbrain parkinsons disease |
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Neurons of the substantia nigra are part of the ___ and release ___ (a neurotransmitter) to control involuntary muscle activities. *Brainstem, acetylcholine *Midbrain, dopamine *Midbrain, acetylcholine |
Midbrain, dopamine |
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Inactivation (decreased metabolism) of the ___ leads to sleep. ___ can not wake a person. *Reticular activating system (RAS), odors *Hippocampus, odors *Cerebellum, bright lights |
Reticular activating system (RAS), odors |
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___ are neuroglia that phagocytosize microbes and damaged neurons of the ___. *Astrocytes, CNS *Ependymal cells, CNS *Microglia, CNS |
Micgroglia, CNS |
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Networks of capillaries, called the ___, are covered by ___ that produce CSF *Neurolemma, ependymal cells *choroid plexus, ependymal cells *choroid plexus, microglia |
choroid plexus, ependymal cells |
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CSF is produced by neuroglia called ___ and provides the optimal cation concentration for ___. *ependymal cells, action potential propagation *microglial cells, action potential propagation *astrocytes, BBB formation |
ependymal cells, action potential propagation |
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the pons is part of the ___ and plays a role in receiving sensory impulses from ___. *Diencephalon, teeth, tongue & part of the face *Brain stem, heart *brain stem, teeth, tongue & parts of the face |
brain stem, teeth, tongue and parts of the face |
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the pons is part of the ___ and plays a role in sending motor impulses to ___ *Diencephalon, jaw *Brain stem, heart *Brain stem, jaw |
brain stem, jaw |
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the pineal gland is part of the ___ and secretes more of the hormone melatonin to promote ___. *Diencephalon, drowsiness in dark *brain stem, drowsiness in dark *brain stem consolidation of memories |
brain stem, drowsiness in dark |
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the hypothalamus releases ___ to trigger the release of ___ by the pituitary gland, which then results in release of glucocorticoids by the adrenal glands. *corticotropin-RH, adrenal corticotrophic H *adrenal corticotrophic H, corticotropin RH *corticotropin RH, luteinizing H |
corticotropin-releasing hormone, adrenal corticotrophic hormone |
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the thrist center consists of cell bodies in the ___ that detect ___ conditions outside the cell. *hippocampus, hypotonic *hippocampus, hypertonic *hypothalamus, hypertonic |
hypothalamus, hypertonic |
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the hypothalamus releases ___ to trigger release of ___ by the pituitary gland, which then regulates the ovaries and testes.
*gonadotropin-RH, oxytocin *gonadotropin RH, follicle stimulating H & luteinizing H *gonadotropin-releasing H, adrenal corticotrophic H |
gonadotropin releasing hormone, follicle stimulating hormone and luteinizing hormone
|
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they hypothalamus releases ___to trigger release of ___ by the pituitary gland, which then regulates muscle mass and fat distribution. *growth hormone RH, groth hormone *cortiotrophin RH, oxytocin *growth hormone RH (GHRH), oxytocin |
growth hormone-releasing hormone (GHRH), oxytocin |
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the hypothalamus produces ___ that is then released by the ___ to promote ___ and pleasure from sexual intercourse. *oxytocin, posterior pituitary gland, release of breast milk *oxytosin, anterior pituitary gland, release of breast milk *polactin, posterior pituitary gland, the release of breast milk |
oxytosin, anterior pituitary gland, release of brest milk |
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the ___ has a high number of flucocorticoid receptors and shrinks as a result of ___. *amygdala, multiple sclerosis *hypothalamus, Alzheimers disease *hippocampus, alzheimers disease |
hippocampus, alzheimers disease |
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prolactin is a hormone produced by the ___ and is involved in the ___ of breast milk. *hypothalamus, release *hypothalamus, production *anterior pituitary, release |
hypothalamus, production |