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34 Cards in this Set

  • Front
  • Back
Polyspermy
Multiple sperm fertilize the egg
Fertilization envelope
Resists the entry of additional sperm nuclei, slow block
Blastomere
Small cells formed by the cleavage partitions of one large cell
Blastula
Ball of cells with a fluid-filled cavitiy
Blastocoel
Fluid-filled cavity within the blastula
Vegetal pole
End of the egg where yolk is concentrated
Animal pole
End of the egg where yolk is significantly less concentrated
Gastrula
Two or three layered embryo with a primitive gut
What is the concept of preformation?
The idea that the egg or sperm contains a miniature infant, or “monoculus,” which becomes larger during development
Distinguish cell differentiation from morphogenesis.
Cell differentiation: Specialization of cells in structure and function
Morphogenesis: The process by which an animal takes shape
What is a model organism?
Species that are representative of larger group and easily studied. Ex. Drosophila and Caenohabditis elegans
What constitutes the three stages of embryonic development post fertilization?
Cleavage: Cell division creates a hollow ball of cells called a blastula
Gastrulation: Cells are rearranged into a three-layered gastrula
Organogenesis: Three layers interact and move to give rise to organs
What is the acrosomal reaction?
Triggered when the sperm meets the egg. Acrosome at tip of the sperm releases hydrolytic enzymes that digest material surrounding the egg.
What is an acrosomal process?
Sperm structure that elongates and penetrates that coat of the egg. Molecules on the tip of the process adhere to specific sperm receptor proteins that extend from the egg plasma membrane through the surrounding meshwork of extracellular matrix.
What happens upon fusion of sperm and egg membranes?
The fusion triggers depolarization of the membrane, a fast block to polyspermy
What would happen if polyspermy were not prevented?
There would be multiple fusions which would cause triploid+ embryos.
How does the cortical reaction differ in mammals compared to other vertebrate?
Follicles present. The cortical reaction modifies the zona pellucida, the extracellular matrix of the egg, as a slow block to polyspermy. There is no fast block, no depolarization.
What happens after fusion of the sperm and egg membranes in mammals?
The entire sperm is taken into the egg. The nuclei of the sperm and egg do not immediately fuse, but instead share a common spindle during the first mitotic division of the zygote.
What is meant by the term polarity?
Polarity: Distribution of yolk (stored nutrients)
What is the gray crescent a marker of?
Marks the future dorsal side of the embryo
Contrast holoblastic and meroblastic cleavage?
Holoblastic cleavage: Complete division of the egg (occurs in species with little or moderate amounts of yolk)
Meroblastic cleavage: Incomplete division of the egg, restricted to animal hemisphere (occurs in species with yolk-rich eggs)
In meroblastic cleavage where does cleavage and formation of the blastocoel occur?
Restricted to animal hemisphere.
What are the three germ layers produced by gastrulation?
Ectoderm: Outer layer
Endoderm: Lines digestive tract
Mesoderm: Partly fills space between the endoderm and ectoderm
What process results in the formation of the archenteron?
Invagination: Vegetal plate buckles inward, forms a cavity called the archenteron
What is the open end of the archenteron called and what does it eventually become in the adult animal?
The blastopore will become the anus
What happens during organogenesis?
Various regions of the germ layers develop into rudimentary organs.
What is an amniote?
Amniote: Organisms with embryos that develop in fluid-filled sacs in a shell or uterus
During amniote development, four extraembryonic membranes form around the embryo, what are they called and what is their function?
Chorion: Gas exchange
Amnion: Encloses the amniotic fluid
Yolk sac: Encloses the yolk
Allantois: Disposes of waste products and contributes to gas exchange
What is the fate of the inner cell mass in mammals?
Develops into the embryo and forms the extraembryonic membranes
Which part of the blastocyst in mammals initiates implantation into the uterine wall?
Trophoblast: Outer epithelium of the blastocyst
What cells and tissues form the placenta?
Trophoblast, mesodermal cells from the epiblast, and adjacent endometrial tissue
What functions are carried out by the cytoskeleton?
Drives cell migration, the active movement of cells. Reorganization of the cytoskeleton is associated with morphogenetic changes in embryonic tissues. Changes cell shape (ex. neural tube formation)
What is meant by the term convergent extension?
Convergent extension: A morphogenetic movement in which cells of a tissue become narrower and longer
What is the cortical reaction? What does it accomplish?
Cortical reaction: Cortical granules in the egg fuse with the plasma membrane and harden to form the fertilization envelope. The contents clip off sperm-binding receptors and cause the fertilization envelope to form. Slow block to polyspermy.