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206 Cards in this Set

  • Front
  • Back
Name the cavaties of the ventral body.
Thoracic, and abdominopelvic
Name the subdivisions of the thoracic cavity
1. pleural cavity (houses lungs)
2. meidastinum (contains pericardial cavity, surronds thoracic organs)
3. pericardial cavity (encloses heart)
Name the subdivisons of the abdominopelvic cavity.
1. abdominal (contains stomach, intestines, spleen, and liver)
2. pelvic cavity (contains urinary bladder, reproductive organs, and rectum)
What does the parietal serosa line?
internal body walls
What does the visceral serosa cover?
internal organs
Describe the sagittal plane
divides the body vertically into left and right planes
Describe the frontal plane
divides the body vertially into anterior and posterior parts
Describe the transverse plane
divides the body horizontally into superior and inferior parts
What is the role of the dorsall cavity?
to protect the nervous system
What are teh two divisons of the dorsal cavity?
1. cranial cavity
2. vertebral cavity
What is a neutron?
a neutral subatomic partical
What is a cation?
an electrically charged partical due to loss of an electron
Waht is a molecule?
smallest particle of a compound that still retains its propertites
What is an atom?
smallest particle of an element that retains its properties
What range describes an acid on the pH scale?
0-6.99
What range describes a neutral on the Ph scale?
7, the closes is milk or blood
What range describes a base on the Ph scale?
7.1 to 14
What is the function of triglycerides?
energy storage, insulation, protection
What is the function of the nuclear envelope?
contains pores for mRNA to travel with instruction
What is the function of Rough ER
proteins syntheis
Waht is the function of the GOldi apparatus?
distribution and packaging and modify proteins
What is the funciton of the peroxisome
contian digestive enzymes
What is the function of chromatin
site where DNA is stored
What is the function of nucleoulus?
makes mRNA
What is the function of Smooth Er
fat synthesis
What is the function of mitochondrion?
produce ATP
What is the function of centrioles?
plays a role in cell division
What is the function of teh cytoskeleton?
give support and flexibility
What are the types of membrane transport?
1. active
2. passive
Facilitated diffusion is a type of passive transport and it uses ___.
carrier proteins
Is osmosis a passive process?
yes
What are integral proteins and their function?
firmly inserted into the membrane, transport proteins, enzymes, or receptors
Describe microtubules
hollow cytoskeletal elements that act as organizers for the cytoskeleton
What are the actual sites of proteins syntheiss
ribosomes
Positive feedback mechanisms ___ the original simulus
increase
Isotopes differ each other in the number of ____ contained
neutrons
Does facilitated diffusion always require a carrier proteins
no
What do negative feedback mechanisms do?
work to prevent sudden severe changes withing the body
What are some survival needs of the body?
atomospheric pressure, oxygen, nutrients, water
What do oils have that lipids dont
a high degree of unsturated bonds
A chemical reaction in which bonds are broken usually is associated with
release of energy
HOw are carbohydrates and proteins built up
by removing water molecule between each two units
What is transcytosis?
transporting something from one side of the cell to another by using exocytosis
Ionic bonds
formed by transfer of electrons between atoms
Covalent bonds
sharing of two or more valence shell electrosn
atomic number =
number of protons
What is Interphase?
the period from cell formation to cell division
What phase is the cell in most of the time?
Interphase
What are the four subphases of the cell cycle?
Gap 1, Gap 0, Synthetic, and Gap 2
What occurs in Gap 1 of Interphase?
vigorous growth and metabolism
What occurs in Gap 0 of Interphase?
cells permanetly cease dividing
What occurs in the synthetic phase of Interphase?
DNA replicates
What occurs in Gap 2 of Interphase?
Prperation for division
What is the first step in DNA replication?
the DNA helices begin unwinding from the nucleosomes
Each nucleotide strand serves as a template for __________.
building a new complementary strand
What is the end result of DNA replication and what is this process called?
Two DNA molecules fromed from the original, this process is called semiconservative replication
The mitotic phase of the cell refers to___ ___.
cell division
What is the purpose of cell division?
body growth and tissue repair
Where does mitosis NOT occur?
mature cells of the nervous tissue, skeletal muscle, and cardiac muscle
What are the four stages of mitosis?
Prophase
Meatphase
Anaphase
Telophase
What is cytokenisis?
division of cytoplasm by clevage furrow
What is the state of the chromosomes in Prophase?
they become visible and each have two chromatids attached at a centromere
What are the events in Prophase?
1. centrosomes seperate and migrate toward opposite directions
2. spindle forms
3. nuclear envelope fragments
4. microtubles attach to centromere
5. poles are pulled apart
What events occur in Metaphase?
the centromeres of chromosomes are aligned at the equator
Anaphase is the ____phase of mitosis.
shortest
What events occur in Anaphase?
1. centromeres of chromosoms split and each chromatid becomes a chromosome
2. chromosomes are pulled apart to opposite poles
When does telophase begin?
when chromosome movement stops
What events occur in telophase?
1. the two sets of chromosomes uncoil to perform chromatin
2. a new nuclear membrane forms around each chromatin mass
3. the nucleoli reappear and the spindle dissapear
When does cytokenisis occur?
during late anaphase
How does cytokenisis occur?
a ring of actin filaments contracts to form a clevage furrow creating two daugther cells containing a nucleus IDENTICAL to the original
What are the "go" signals in the cell to control division?
critical volume of cell and chemicals such as hormones, cyclins, and growth factors
What are the "stop" signals in cell division?
contact inhibition, and growth inhibiting factors produced by repressor genes
DNA is the _____ for protein synthesis.
blueprint
What is rRNA?
a structural component of ribosomes
What is the function of tRNA?
bind to amino acids and pair with bases of codons of mRNA to begin process of protein synthesis
What is the purpose of transcription?
to transfer the DNA gene base sequence to a complementary base sequence of an mRNA
What does the transcription factor do?
1. loosens histones from DNA in area to be transcribed
2. binds to promoter, a DNA sequence specifying start site of gene to be transcribed
3. mediates the binding of RNA polymerase to promoter
What does translation do?
converts base sequence of nucleic acids into the amino acid sequence of proteins
What is involved in translation?
mRNA, tRNA, rRNA
What are the steps of protein synthesis in the ER?
1. protein enters ER
2. sugar groups may be added to the protein and its shape may be altered
3. the protein is enclosed in a vesicle for transport to the Golgi apparatus
What are two active processes in cells? What do they use to move solutes across a plasma membrane?
Active Transport and Vesicular Transport, ATP
What is Active Transport?
Movement of solutes against the concentration gradient
What are the two types of active transport?
Primary and Secondary
How does primary active transport happen?
energy from hydrolisis ATP cause shape cahnge in the transport proteins so that bound solutes are pumped across the membrane
What is secondary active transport?
when energy is stored in ionic gradients and is used indirectly to drive transport of other solutes
Endocytosis and Trancytosis involve what?
formation of protein coated vesicles
Endocytosis and Trancytosis are _____and are therefore very ________.
receptor mediated, selective
What types of tissue are there?
epithelial
connective
muscle
nerve
What is the job of the nevous tissue and where can it be found?
internal communication, brain, spinal cord and nerves
What is the job of muscle tissue?
contract to cause movement
What is the job of epithelial tissue?
forms boundaries between different enviornments, protects, secretes, absorbs, and filters
What is the job of connective tissue?
support, protect, and bind other tissues together
Where can connective tissue be found?
on the bones, on the tendons, and on fat and other padding tissues
Where are the two main locations of epithelial tissue?
1. Covering and lining epithelia (on external and internal surfaces)
2. glandular epithelia (secretory tissue on glands)
What are the characteristics of epithelial tissue?
1. the cells have polarity with and apical (upper) and basal (lower) surfaces
2. the cells are always closely packed
3. it is supported by a connective tissue reticular lamina
4. It is not vasular
5. It has a high rate of regeneration
Considering layering, epithelium can either be ___ or ___.
simple or stratified
There are three cell shapes in epithelial tissue.
squamous, cubodial, and columnar
Describe simple squamous epithelium.
Single layer of flattened cells with disc-shaped cental nuclei, it is the simplest of all epithelium
What is the function of simple squamous epithelium?
allows passage of material by diffusion and filtration in sites where protection is not important, it secretes lubricating substances in the serosa
Where is simple squamous epithelium located?
kidney, air sacs of lungs, lining of heart, blood vessels, lympatic vessels, and lining of ventral body cavity (serosae)
Name two other locations of simple squamous epithelium.
endothelium, and mesothelium
Describe simple cubodial epithelium?
single layer of cubelike cells with large, spherical central nuclei
What is the function of simple cubodial epithelium?
secretion and absorbtion
What are the location of simple cubodial epithelium?
kidney tubules, ducts and secretory parts of small glands, and ovary surface
Describe simple columnar epithelium
single layer of tall cells, some have cilia, it may contail a layer of mucus secreting goblet cells
What are the location of the nonciliated simple columnar epithelium?
digestive tract, gallbladder, and excretory ducts from some glands
What are the location of the ciliated simple columnar epithelium?
lining bronchi, uterine tubes, and some regions of the uterus
Describe pseudostratified columnar epithelium
single layer of cells of differing heights, some not reaching the free surface (apical); the nuclei are seen at different levels
What is the function of pseudostratified columnar epithelium?
secretion of mucus, propulsion of mucus by ciliary action
What are the location for the nonciliated pseudostratified epithelium?
males sperm carrying ducts, ducts of large glands
What are the locations of ciliated pseudostratified epithelium?
trachea, most of upper respiratory tract
Describe stratified squamous epithelium
composed of several layers, basal cells are cubodial or columnar and metabolicaly active; surface cells are squamous
What is the function of stratified squamous epithelium?
protect underlying tissues in areas subjected to absorption
What are the location of nonkeratinized stratified sqamous epthelium?
most linings of the esophagus, mouth and vagina
Whear is keratinized stratified squamous epithelium found?
in the epidermis of the skin
Describe stratified cubodial epithelium.
typically two cell layers thick, quite rare
Where is stratified cubodial epithelium found?
some sweat and mammary glands
Where is stratified columnar epithelium found?
limited distribution, small amounts in the pharynx, male urethra, and lining some glandular ducts
Describe transistional epithelium.
Resembles both stratified sqamous and stratified cubodial
What is the functionof transistional epithelium?
stretches readily and permits distension of urinary organ by contained urine
What are the location of transistioal epithelium?
ureters, urinary bladder, and part of the urethra
What is a gland?
one or more cells that makes and secretes an aqueous fluid
How are glands classified?
by site of production release (endocrine or exocrine) and realtive number of cells forming the gland
What are endocrine grands and what do they do?
ductless glands, secrete hormones that travel through lymp or blood to target organs
There are ___ exocrine glands than endocrine glands.
more
What do exocrine glands do?
secrete products into ducts that are released onto body surfaces or into body cavities
What is the most important unicellular exocrine gland?
goblet cells
What are multicellular exocrine glands composed of?
a duct and a secretory unit
How are multicellular exocrine glands classified?
by duct type and structure of there secretory units
What are tge two modes of secretion?
merocrine and holocrine
What in merocrine secretion?
when products are secreted by exocytosis (ex. pancreas, sweat and salivary glands)
What is holocrine secretion?
when products are secreted by rupture of glands (ex. sebaceous glands)
What is the most abundant and widely distributed type of tissue?
connective tissue
What are the four classes of connective tissue?
1. connective tissue proper
2. cartilage
3. bone tissue
4. blood
What are the major function of connective tissue?
1. insulation
2. protection
3. binding and support
4. transportation
What are some characteristics that all connective tissues share?
1. mesenchyme is their common tissue of origin
2. some have blood vessels
3. the cells are seperated by nonliving extracellular matrix
What is the extracellular matrix in connective tissue made of?
ground substance and fibers
What is collagen?
the white fibers, they are the strongest and most abundant of fibers
What does collagen provide to connective tissue?
high tesile strength
What is elastic fibers?
networks of long, thin, elastin fibers that allow connective tissue to stretch
What is reticular fibers?
short, fine, highly branched collagenous fibers in connective tissue, creates a meshwork
_____ _____ can become any cell and can be found in ___.
stem cells, bone
Describe loose connective tissue, areolar
Gel-like matrix with all three fiber types
What cells are found in loose connective tissue areolar?
mast cells, fibroplasts (main cell type), and some white blood cells
What is the function of loose connective tissue, areolar?
wraps and cushions organs, its macrophages phagocitize bacteria, palys an important role in inflammation, holds and conveys tissue fluid
What are the location of loose connective tissue, AREOLAR?
under epithelium of the body, forms lamina propria, packages organs, and surronds capillaries
Describe the loose connective tissue adipose.
has a matrix, closely packed adipocytes, nucelus pushed to the side
What is the function of the loose connective tissue adipose?
provide a reserve for food fuel; insulate against heat loss, and support and protect organs
Where is the loose conncective tissue adipose located?
under the skin the hypodermis; around kidneys and eyeblass, within abdomen, and in breasts
Describe dense connective tissue, dense regular.
primarily parralel collagen fibers; a few elastic fibers
What is the major cell type of dense connective tissue, dense regular?
fibroblast
What is the funciton of dense connective tissue, dense regular?
attaches muscle to bones or to muscles, attaches bones to bones; withstands great tinsle stress when pulling force is applied in one direction
Describe dense connective tissue, elastic.
dense regular connective tissue containing a high proportion of elastic fibers
What are the location of the cartilage hyaline?
forms most of the embryonic skeleton; covers the ends of long bones in joint cavaties; forms costal cartilages of the ribs; cartilage in the nose, trachea and larynx
Describe the cartilage elastic.
similar to hyaline but more elastic fibers are present in the matrix
What is the function of the cartilage elastic?
maintains the shape of a structure while allowing great flexibility
What are the locations of the cartilage elastic?
external ear, and epiglottis
Describe the cartilage fibrocartilage.
matrix similar to but less firm than that of hyaline cartilage, predominated by collagen
Describe bone.
hard, calcified matrix containing many collagen fibers; very well vascularized
Describe skeletal muscle.
long, cyndrical, multinucleated cells, striated
What is the function of skeletal muscle?
voluntary movement; locomotion
Skeletal muscle cells are different because they
undergo miosis without cytokenisis
Describe cardiac muscle.
Branching, striated, generally uninucleated that meet at junction called intercalated discs
What is the function of cardiac muscle?
propel blood into teh circulation
Describe smooth muscle.
spindle shaped cells, no striations, cells are arranged to form sheets
What is the function of smooth muscle?
propels substances or objects along internal passage ways; involuntary
What is the location of smooth muscle?
walls of hollow organs
What membrane is the skin?
cutaneous membrane
What is the mucous membranes called?
mucosae
What does the mucosae membrane line?
body cavaties open to the exterior
What does the serosae line?
internal body walls
What are the steps in tissue repair?
1. inflammation
2. organization and restored blood supply
3. regeneration and fibrosis
What are the primary germ layers?
ecotderm, mesoderm, and endoderm
The ectoderm forms the ____.
nervous tissue
The mesoderm froms the___.
muscle and connective tissue
The endoderm forms the ___.
epithelium
Tissue repair requires cell to ____ and ____.
repair
migrate
Repair can occur in two ways:
regeneration and fibrosis
The type of repair used depends upon two things:
the type of tissue damaged and severity of the injury
replacement of destroyed tissue with the same kind of tissue is _____
regeneration
proliferation of fibrous connective tissue called scar tissue is ________
fibrosis
What are the three steps in tissue repair?
1. inflammation
2.organization
3.regneration and permanent repair
What are the steps in inflammation of tissue repair?
1. there is a release of inflammatory chemicals by tissue cells, macrophages, and mast cells
2. dilation of the blood vessel occurs and an increase of vessel permeability
What does the dilation of blood vessels and the increase of vessel permeability cause?
1. white blood cells and plasma containing cloting proteins and antibodies to seep into the injured area
2. clot forms and stops the loss of blood and holds the edges of the wound together
3. the part of the clot exposed to the air forms a scab
What are the steps in organization of tissue repair?
1.the clot is replaced by granulation tissue, which restores the vascular supply

2. fibroblasts produce collagen fibers that bridge the gap

3. macrophages phagocytize cell debris

4. surface epithelial cells multiply and migrate over the granulation tissue
What are the steps in regneration and fibrosis of tissue repair?
1. surface epithelium starts to regenerate growing under the scab

2. the scab detaches

3. fibrous tissue matures: epithelium thickens and begins to resemble adjacent tissue

4. results in a fully regnerated epithelium with underlying scar tissue
In simple infections healing is done only by _____
regneration
Severe infections lead to _____.
scar tissue
Name some tissues that regnerate very well:
epthelial

bone

areolar connective tissue

dense irregular connective

blood forming tissue
Name some tissues that dont regnerate well:
cardiac muscle

nervous tissue
In non-regnerative tissues severe wounds are replaced by_____.
fibrosis
What are some complication seen with scar tissue?
1. if fomed on an organ it may hinder the function of the organ

2. movement of substances may be blocked

3. it can hamper the muscles ability to contract ( leading to heart failure, immobilize joints)
How many americans will develop skin cancer at some point in their life
1 in 5
What are some risk factors that can cause skin cancer?
overexposure to UV radiation

frequent irritation of the skin with chemicals, infections, or trauma

requent over exposure to the sun
List the three major types of skin cancer in order from least threating to most.
1. basal cell carcinoma

2. squmous cell carcinoma

3. melanoma
Describe basal cell carcinoma
stratum basale cells proliferate and slowly invade dermis and hypodermis, occur in sun exposed areas of the face, create a shiny dome, slow growing, 99% cured
Describe squamous cell carcinoma.
involves keratinocytes of stratum spinosum, most common on scalp and ears lower lips and hands, grows rapidly,
Describe melanoma
involves melancoytes, highly metastic and resistant to chemotherapy, very dangerous, can begin wherever pigment is, treated by surgery or radiation
4 characteristics of melanoma
1. asymmetry
2. borders indentations
3. color is black, brown, tan, red or blue
4. diameter is larger than 6mm
a burn is simply ______
denatured protein, tissue damage, and cell death
Burns can be caused by
electricity, chemicals, radiation, and heat
What is the biggest threat concerning burns?
dehydration and electrolyte imbalance, causes renal shutdown and circulatory shock
Describe a first degree burn
epidermal damage only
Describe a second degree burn
epidermal and upper dermal damage
describe a third degree burn.
entire thickness of the skin is burned
Burns are critcal if:
25% of the body has second degree burns

10% of the body has third degree burns or on face hands or feet