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22 Cards in this Set
- Front
- Back
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Obligate intracellular pathogens that cannot generate their own ______ and depend on the______cell’s biochemical machinery for it’s replication, transcription, and translation.
what is it? |
energy;
host; VIRUS! |
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a virus consists of a nucleic acid genome (DNA or RNA) surrounded by a protein coat called a ______ (together called a _______).
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capsid
nucleocapsid |
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a viral genome encodes only a few structural and nonstructural proteins required for viral _________.
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replication!
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Capsid is composed of subunits called _______encoded by the viral genome.
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capsomeres
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_______ is the physical particle in the extra-cellular phase, which is able to spread to new host cells
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virion
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a viruses nucleic acids consist of _____ & ______
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DNA & RNA
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do you culture a virus on media?
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NO! too small
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size of virus in nm?
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30-300nm
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nucleocapsid + glycoprotein and membrane= ?
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enveloped virus
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______ functions as a shell to protect the genome from nucleases
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capsid
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________ provides attachment to host cell receptors during infection via glycoproteins
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capsid
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_____ is a single or double protein shells that consist of one or a few structural proteins
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capsid
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Capsids may be_______ or _________ in shape
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icosahedral or helical
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-Can survive in the gastrointestinal tract
-Retain infectivity on drying -Survive well on environmental surfaces -Spread easily via fomites -Must kill host cells (lysis) for release of mature virus particles -Humoral antibody response may be sufficient to neutralize infection |
naked capsid viruses properties!
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______ _____ _____ are resistant to these!:
-Drying -Heat -Detergents -Acids -Proteases |
naked capsid viruses
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_______ is sensitive to:
-Drying -Heat -Detergents -Acid |
envelope!
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consequences of _______ :
-Must stay wet during transmission -Transmission in large droplets and secretions -CANNOT survive in the GI tract -Do NOT need to kill cells in order to spread -May require both a humoral and a cellular immune response for protection and control |
enveloped viruses
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borna disease virus, host is vertebrate, genus is?
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bornavirus
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vesicular stomatitis indiana virus, host is vertebrate & insect, family rhabdoviridae, genus is?
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vesiculovirus
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rabies virus, host is vertebrate, family rhabdoviridae, genus is ?
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lyssavirus
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bovine ephemerovirus fever virus, host is vertebrate & insect, family rhabdoviridae, what is genus?
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ephemerovirus
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infectious hematopoetic necrotic virus, host is vertebrate, family rhabdoviridae, what is genus?
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novirhabdovirus
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