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22 Cards in this Set

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  • Back
Obligate intracellular pathogens that cannot generate their own ______ and depend on the______cell’s biochemical machinery for it’s replication, transcription, and translation.
what is it?
energy;
host;
VIRUS!
a virus consists of a nucleic acid genome (DNA or RNA) surrounded by a protein coat called a ______ (together called a _______).
capsid
nucleocapsid
a viral genome encodes only a few structural and nonstructural proteins required for viral _________.
replication!
Capsid is composed of subunits called _______encoded by the viral genome.
capsomeres
_______ is the physical particle in the extra-cellular phase, which is able to spread to new host cells
virion
a viruses nucleic acids consist of _____ & ______
DNA & RNA
do you culture a virus on media?
NO! too small
size of virus in nm?
30-300nm
nucleocapsid + glycoprotein and membrane= ?
enveloped virus
______ functions as a shell to protect the genome from nucleases
capsid
________ provides attachment to host cell receptors during infection via glycoproteins
capsid
_____ is a single or double protein shells that consist of one or a few structural proteins
capsid
Capsids may be_______ or _________ in shape
icosahedral or helical
-Can survive in the gastrointestinal tract
-Retain infectivity on drying
-Survive well on environmental surfaces
-Spread easily via fomites
-Must kill host cells (lysis) for release of mature virus particles
-Humoral antibody response may be sufficient to neutralize infection
naked capsid viruses properties!
______ _____ _____ are resistant to these!:
-Drying
-Heat
-Detergents
-Acids
-Proteases
naked capsid viruses
_______ is sensitive to:
-Drying
-Heat
-Detergents
-Acid
envelope!
consequences of _______ :
-Must stay wet during transmission
-Transmission in large droplets and secretions
-CANNOT survive in the GI tract
-Do NOT need to kill cells in order to spread
-May require both a humoral and a cellular immune response for protection and control
enveloped viruses
borna disease virus, host is vertebrate, genus is?
bornavirus
vesicular stomatitis indiana virus, host is vertebrate & insect, family rhabdoviridae, genus is?
vesiculovirus
rabies virus, host is vertebrate, family rhabdoviridae, genus is ?
lyssavirus
bovine ephemerovirus fever virus, host is vertebrate & insect, family rhabdoviridae, what is genus?
ephemerovirus
infectious hematopoetic necrotic virus, host is vertebrate, family rhabdoviridae, what is genus?
novirhabdovirus