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22 Cards in this Set

  • Front
  • Back
The transmission of impulses from the nerve to the striated muscle at the neuromuscular junction is mediated by the release of: [1]
A. Adrenaline
B. Acetylcholine
C. Cholinesterase
D. Norepinephrine
E. Acetaldehyde
B. Acetylcholine
Skeletal muscles are: [2]
A. Composed of either type I (slow) or type II (fast) fibers
B. Composed of rapidly dividing cells
C. Composed of nondividing cells that can be stimuÂlated to enter mitosis by a variety of cytokines
D. In close contact with nerves
E. Major storage site of calcium and phophate
D. In close contact with nerves
Spastic contraction of muscle known as tetany is caused by: [3]
A. Hypercalcemia
B. Hypoparathyroidism
C. Hyperthyroidism
D. Hyponatremia
E. Hypophosphatemia
B. Hypoparathyroidism
Botulism, a disease caused by a toxin from Clostridium botulinum, is marked by: [4]
A. Tetany
B. Convulsions
C. Paralysis of muscles
D. Loss of sensation
E. Hypercalcemia
C. Paralysis of muscles
All the following are autoimmune diseases affecting the muscles except: [5]
A. Myasthenia gravis
B. Rheumatoid arthritis
C. Systemic lupus erythematosus
D. Duchenne-type muscular dystrophy
E. Dermatomyositis
D. Duchenne-type muscular dystrophy
Destruction of muscle fibers in polymyositis is characterized by a release of enzymes, the most specific for muscle disease of which is: [6]
A. Lactate dehydrogenase
B. Acid phosphatase
C. Alkaline phosphatase
D. Creatine kinase
E. Alanine aminotransferase
D. Creatine kinase
Peripheral motor neurons are extensions of nerve cells that are typically located in the: [7]
A. Cortex of the brain
B. Basal ganglia
C. Pons
D. Medulla oblongata
E. Anterior horn of the spinal cord
E. Anterior horn of the spinal cord
Which of the following is a typical "upper neuron injury"? [8]
A. Polymyositis
B. Guillain-Barre syndrome
C. Spinal cord injury in traffic accident
D. Diabetic neuropathy
E. Lead poisoning
C. Spinal cord injury in traffic accident
Following wallerian degeneration, the nerve function is restored by the: [9]
A. Regeneration of dendrites from the perikaryon
B. Regeneration of the axon from the peripheral Parts of the transected nerve
C. Regeneration of the axon from the proximal portion of the transected axon
D. Loss of the perikaryon
E. Loss of the Nissl substance
C. Regeneration of the axon from the proximal portion of the transected axon
The first symptoms of myasthenia gravis among women appear most often in which age group? [10]
A. 0-5 years
B. 5-20 years
C. 20-35 years
D. 35-50 years
E. Older than 50 years
C. 20-35 years
Almost all patients with myasthenia gravis show: [11]
A. Signs of muscle degeneration
B. Regrouping of type I and type II muscles
C. Muscle atrophy
D. Antibodies to acetylcholine
E. Antibodies to acetylcholine receptor
E. Antibodies to acetylcholine receptor
Patients with myasthenia gravis given edrophonium, an antagonist of cholinesterase, show: [12]
A. Aggravation of symptoms
B. Complete paralysis
C. Temporary improvement of muscle weakness
D. Reduced levels of circulating antibodies
E. Reduced calcium in blood
C. Temporary improvement of muscle weakness
A patient with myasthenia gravis was found to have an anterior mediastinal mass. This mass proved to be a tumor. Most likely it is a: [13]
A. Thyroid adenoma
B. Parathyroid adenoma
C. Neuroblastoma
D. Smooth muscle cell tumor
E. Thymoma
E. Thymoma
Duchenne-type muscular dystrophy is inherited as a(n): [14]
A. Autosomal dominant trait
B. Autosomal recessive trait
C. Sex-linked recessive trait
D. Sex-linked dominant trait
E. Polygenic trait
C. Sex-linked recessive trait
Symptoms of muscle weakness in Duchenne-type dystrophy begin in: [15]
A. Preschool children
B. Elementary school children
C. High school children
D. College-level teenagers
E. Adults
A. Preschool children
Which of the following muscular dystrophies involves the same gene as Duchenne-type dystrophy? [16]
A. Becker's dystrophy
B. Limb-girdle dystrophy
C. Facioscapulohumeral dystrophy
D. Myotonic dystrophy
E. Werdnig-Hoffmann disease
A. Becker's dystrophy
Frontal baldness, testicular atrophy, and muscle spasm arc typical of which autosomal dominant muscular dystrophy? . [17]
A. Duchenne's
B. Becker's
C. Facioscapulohumeral
D. Limb-girdle
E. Myotonic
E. Myotonic
Which is the most common cause of muscle weakness and/or paralysis in infants and children? [18]
A. Duchenne-type dystrophy
B. Becker's dystrophy
C. Cerebral palsy
D. Dermatomyositis
E. Infectious myositis
C. Cerebral palsy
Which of the following viruses is the best-known cause of myositis? [19]
A. Herpesvirus type I
B. Herpesvirus type II
C. CMV
D. Coxsackie virus
E. Mumps virus
D. Coxsackie virus
Muscle inflammation characterized by infiltrates of lymphocytes and plasma cells is most typical of: [20]
A. Muscular dystrophy
B. Muscular atrophy
C. Trichinella spiralis infection
D. Polymyositis
E. Myasthenia gravis
D. Polymyositis
Malignant tumor of striated muscle is called: [21]
A. Leiomyosarcoma
B. Rhabdomyosarcoma
C. Liposarcoma
D. Synovial sarcoma
E. Malignant fibrous histiocytoma
B. Rhabdomyosarcoma
The most common histologic type of soft tissue sarcoma in adults is: [22]
A. Liposarcoma
B. Malignant fibrous histiocytoma
C. Rhabdomyosarcoma
D. Leiomyosarcoma
E. Synovial sarcoma
B. Malignant fibrous histiocytoma