Actcm Pathol Ch5 Genetics

Front 1

Anencephaly [1]
A. Autosomal donrinant inheritance
B. Autosomal recessive inheritance
C. X-linked recessive inheritance
D. X-linked donrinant inheritance
E. Multifactorial inheritance

Back 1

E. Multifactorial inheritance

Front 2

Meningomyelocele [2]
A. Autosomal donrinant inheritance
B. Autosomal recessive inheritance
C. X-linked recessive inheritance
D. X-linked donrinant inheritance
E. Multifactorial inheritance

Back 2

E. Multifactorial inheritance

Front 3

Duchenne's muscular dystrophy [3]
A. Autosomal donrinant inheritance
B. Autosomal recessive inheritance
C. X-linked recessive inheritance
D. X-linked donrinant inheritance
E. Multifactorial inheritance

Back 3

C. X-linked recessive inheritance

Front 4

Cystic fibrosis [4]
A. Autosomal donrinant inheritance
B. Autosomal recessive inheritance
C. X-linked recessive inheritance
D. X-linked donrinant inheritance
E. Multifactorial inheritance

Back 4

B. Autosomal recessive inheritance

Front 5

Marfan's syndrome [5]
A. Autosomal donrinant inheritance
B. Autosomal recessive inheritance
C. X-linked recessive inheritance
D. X-linked donrinant inheritance
E. Multifactorial inheritance

Back 5

A. Autosomal donrinant inheritance

Front 6

Hemophilia A [6]
A. Autosomal donrinant inheritance
B. Autosomal recessive inheritance
C. X-linked recessive inheritance
D. X-linked donrinant inheritance
E. Multifactorial inheritance

Back 6

C. X-linked recessive inheritance

Front 7

Hemophilia B [7]
A. Autosomal donrinant inheritance
B. Autosomal recessive inheritance
C. X-linked recessive inheritance
D. X-linked donrinant inheritance
E. Multifactorial inheritance

Back 7

C. X-linked recessive inheritance

Front 8

Fragile X chromosome [8]
A. Autosomal donrinant inheritance
B. Autosomal recessive inheritance
C. X-linked recessive inheritance
D. X-linked donrinant inheritance
E. Multifactorial inheritance

Back 8

C. X-linked recessive inheritance

Front 9

Diabetes mellitus [9]
A. Autosomal donrinant inheritance
B. Autosomal recessive inheritance
C. X-linked recessive inheritance
D. X-linked donrinant inheritance
E. Multifactorial inheritance

Back 9

E. Multifactorial inheritance

Front 10

Familial hypercholesterolemia [10]
A. Autosomal donrinant inheritance
B. Autosomal recessive inheritance
C. X-linked recessive inheritance
D. X-linked donrinant inheritance
E. Multifactorial inheritance

Back 10

A. Autosomal donrinant inheritance

Front 11

Tay-Sachs disease [11]
A. Autosomal donrinant inheritance
B. Autosomal recessive inheritance
C. X-linked recessive inheritance
D. X-linked donrinant inheritance
E. Multifactorial inheritance

Back 11

B. Autosomal recessive inheritance

Front 12

Phenylketonuria [12]
A. Autosomal donrinant inheritance
B. Autosomal recessive inheritance
C. X-linked recessive inheritance
D. X-linked donrinant inheritance
E. Multifactorial inheritance

Back 12

B. Autosomal recessive inheritance

Front 13

Lysosomal lipid storage diseases [13]
A. Autosomal donrinant inheritance
B. Autosomal recessive inheritance
C. X-linked recessive inheritance
D. X-linked donrinant inheritance
E. Multifactorial inheritance

Back 13

B. Autosomal recessive inheritance

Front 14

Neurofibromatosis [14]
A. Autosomal donrinant inheritance
B. Autosomal recessive inheritance
C. X-linked recessive inheritance
D. X-linked donrinant inheritance
E. Multifactorial inheritance

Back 14

A. Autosomal donrinant inheritance

Front 15

Becker's muscular dystrophy [15]
A. Autosomal donrinant inheritance
B. Autosomal recessive inheritance
C. X-linked recessive inheritance
D. X-linked donrinant inheritance
E. Multifactorial inheritance

Back 15

C. X-linked recessive inheritance

Front 16

Most congenital malformations in humans are: [16]
A. Of unknown cause
B. Related to infection during pregnancy
C. Caused by physical agents
D. Caused by drugs
E. Caused by environmental pollution

Back 16

A. Of unknown cause

Front 17

All the following are considered possible causes of the TORCH syndrome except: [17]
A. Toxoplasma
B. Rubella virus
C. Cytomegalovirus
D. Herpesvirus
E. Alcohol

Back 17

E. Alcohol

Front 18

Dilatation of lateral ventricles of the brain found in TORCH syndrome is called: [18]
A. Microphthahnia
B. Chorioretinitis
C. Hydrocephalus
D. Cataract
E. Vesicles

Back 18

C. Hydrocephalus

Front 19

Trisomy of chromosome 21 is typical of: [19]
A. Turner's syndrome
B. Klinefelter's syndrome
C. Down's syndrome
D. WAGR (Wilms' tumor, aniridia, genital malformaÂtions, mental retardation) syndrome
E. Congenital retinoblastoma

Back 19

C. Down's syndrome

Front 20

A male who was tall and slighrly effeminate with eunuchoid body proportions and gynecomastia was found to have a 47, XXY karyotype. These findings are typical of: [20]
A. Turner's syndrome
B. Klinefelter's syndrome
C. Fragile X syndrome
D. Marfan's syndrome
E. Duchenne's muscular dystrophy

Back 20

B. Klinefelter's syndrome

Front 21

An autosomal dominant trait is characterized by all the following except: [21]
A. The trait is apparent in heterozygotes
B. The affected heterozygote has a 50% chance of transmitting the gene to each child
C. The trait is expressed in every generation
D. The unaffected children of a symptomatic carrier do not transmit the trait
E. The gene accounting for the trait can be located on any of the 46 chromosomes

Back 21

E. The gene accounting for the trait can be located on any of the 46 chromosomes

Front 22

Cystic fibrosis may present in newborns with signs of: [22]
A. Dehydration
B. Meconium peritonitis
C. Malabsorption
D. Diarrhea
E. Bronchiectasis

Back 22

B. Meconium peritonitis

Front 23

The most important complication encountered in perÂsons affected by familial hypercholesterolemia is: [23]
A. Xanthoma
B. Atherosclerosis
C. Fatty liver
D. Pancreatitis
E. Subluxation of the lens

Back 23

B. Atherosclerosis

Front 24

The X-linked bleeding disorder caused by a defiÂciency of factor VIII is called: [24]
A. Hemophilia A
B. Hemophilia B
C. Hemosiderosis
D. Hemochromatosis
E. Hemorrhagic fever

Back 24

A. Hemophilia A

Front 25

Children born with a fragile X chromosome suffer from: [25]
A. Muscle weakness
B. Blindness
C. Spinal cord deformities
D. Mental retardation
E. Glucose intolerance

Back 25

D. Mental retardation

Front 26

All the following are routinely used in prenatal diagÂnosis except: [26]
A. Ultrasound
B. Chorionic villus biopsy
C. Fetal skin biopsy
D. Amniotic fluid analysis
E. Maternal blood analysis

Back 26

C. Fetal skin biopsy

Front 27

The most important intracranial complication of the neonatal respiratory syndrome is: [27]
A. Hydrocephalus
B. Periventricular hemorrhage possibly expanding into a hematocephalus
C. Calcification of the basal ganglia
D. Kernicterus
E. Microcephaly

Back 27

B. Periventricular hemorrhage possibly expanding into a hematocephalus

Front 28

Sudden infant death syndrome typically occurs; [28]
A. At the time of birth
B. During the first few hours after birth
C. During the first week after birth
D. During the first month of life
E. Any time between 2 and 9 months of the first year of life

Back 28

E. Any time between 2 and 9 months of the first year of life