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15 Cards in this Set
- Front
- Back
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Mutation?
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Gsoi activating subunit defect
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Is fibrous dysplasia more commonly monostotic or polyostotic?
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Monostotic (good prognosis)
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Clinical features of fibrous dysplasia: what is the appearance of the femoral neck?
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Progressive varus deformity ("shepherd’s crook")
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What is the classic radiographic appearance?
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Ground-glass lesion with distinct margins
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What is the histologic appearance?
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Irregular woven hone
"Chinese letters"“or “aLphabet soup" |
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ln general, what is the treatment of fibrous dysplasia?
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Observation
lf large or symptomatic lesions, curette and bone graft |
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How is an impending pathologic fracture of the upper extremity treated in patients with FD?
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Do not use internal fixation
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What is the treatment of an impending pathologic fracture of lower extremity?
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Open reduction and internal fixation (ORIF)
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ls autograft or allograft preferable in patients with fibrous dysplasia?
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Do not use autograft
Use cortical allograft instead |
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Polyostotic fibrous dysplasia can be associated with what syndrome?
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McCune-Albright syndrome
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What are the two other features of this syndrome?
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Café-au-lait spots (irregular)
Precocious puberty |
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What age group is at risk for osseofibrous dysplasia (OFD)?
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Age <10
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What anatomic location is most commonly involved?
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Tibia
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What is the typical location in bone?
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Cortices
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Osseofibrous dysplasia may be a precursor to what condition?
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Adamantinoma
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