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100 Cards in this Set

  • Front
  • Back

Lymphatic vessels______ cells are different from blood vessel cells

Endothelial

Lymphatic endothelial cells _____ have tight junctions and they don not have a continual basal lamina.


Do or don't


Don't

There are large gaps between the endothelial cells so _____ and large molecules can pass between them.

Lymphocytes

The overlapping endothelial cells make _____ that can open and close. They will open and close due to the _____ of the lymph fluid flowing through the vessel

Valves


Pressure

Can produce lethal hits to infected self cells


Direct activation produced by MHC-1 recognition


Mature from thymic tissues

T cells

Can produce lethal hits to infected self cells


Direct activation produced by MHC-1 recognition


Mature from thymic tissues

T cells

Differentiate into plasma cells when activated


Anti-body mediated immunity


Direct activation produced by MHC 2 recognition

B cells

The classical alternative and ______ pathways all lead to the cleavage of complement C3 into C3a and C3B

Lectin

The classical alternative and ______ pathways all lead to the cleavage of complement C3 into C3a and C3B

Lectin

Those two fragments activate processes that lead to _________inflammation immune clearance and phagocytosis

Enhanced

The classical alternative and ______ pathways all lead to the cleavage of complement C3 into C3a and C3B

Lectin

Those two fragments activate processes that lead to _________inflammation immune clearance and phagocytosis

Enhanced

Inflammation activates and attracts ______ and macrophages, two key cellular agents of pathogen destruction.

Neutrophils

The classical alternative and ______ pathways all lead to the cleavage of complement C3 into C3a and C3B

Lectin

Those two fragments activate processes that lead to _________inflammation immune clearance and phagocytosis

Enhanced

Inflammation activates and attracts ______ and macrophages, two key cellular agents of pathogen destruction.

Neutrophils

Immune Clarence will clear foreign antigens from the ____.

Bloodstream

During Phagocytosis,______ occurs which is the coating of microbial cells

Opsonization

A _____ is an abnormal elevation of body temperature

Fever

A _____ is an abnormal elevation of body temperature

Fever

Yet a fever when allowed to run its course is actually ______

Beneficial

Fever can ______ interferon activity

Promote

Fever can also ______ tissue repair

Accelerate

Fever will prevent the ______ of bacteria and viruses

Reproduction

The birth of T cells takes place in the______ bone marrow

Red

From the red bone marrow cells are sent to mature in the _____

Thymus

After T cells mature in this thymus cells move to the lymphatic tissue and

Organs

In some cases___ cells are made and sent back to the bone marrow

Plasma

When a person is exposed to an antigen for the first time the noon reaction is called the _____ response

Primary

When a person is exposed to an antigen for the first time the noon reaction is called the _____ response

Primary

The appearance of protective_____ is delayed for 3 to 6 days while the naïve B cells multiply and differentiate

Antibodies

As the plasma cells begin secreting anti-body the anti-body_____ begins to rise

Titer

Eventually the primary response will make an immune______ of the antigen

Memory

Name the proper sequence for the processing of proteins produced within the cell

Proteins are broken into fragments, transported to the rough endoplasmic reticulum, combine with the class 1 MHC moved to the Golgi apparatus, then to the plasma membrane

Name the correct sequence for processing proteins originating outside the cell

Proteins are broken into fragments with in a vesicle, which fuses with the golgi vesicles containing class 2 MHC and this complex is transported to the plasma membrane

Foreign antigens presented on class 1 MHC molecules _____

Stimulates cell destruction by activated T cells

True or false


Fragments of form proteins are anti-bodies

False

True or false


Viruses and self proteins are examples of proteins produced inside of the cell

True

Which of the following is true regarding antigens

They contain many different antigenic determinants (epitopes)

Which of the following is true regarding bacterial cells

They have many different epitopes which each bind to specific antibodies

Which of the following is true regarding bacterial cells

They have many different epitopes which each bind to specific antibodies

An individual anti-body is made against______

One epitope of an antigen

True or false


each antigen has one epitope

Balls

True or false


Many different antibodies can be made against a single antigen

True

Which of the following is true when interferon attaches to a cell

The virus can enter the cell but cannot replicate

When interferon from one cell attaches to the second cell______

The recipient cell makes enzymes that degrade mRNA and prevent viral proteins synthesis

Which of the following is true regarding interferon

Interferon is produced by one cell and is used to warn nearby cells of the same type

True or false


Interferon can cause the degradation of mRNA and prevention of the synthesis of viral proteins

True

True or false


Interferon is produced by an animal cell that is infected by a bacterium

False

Which of the following statements is not true of the hepatitis B vaccine

It consists of an internal protein from the virus

The vaccine used to prevent measles consists of live measles viruses. This type of vaccine is likely______.

An attenuated vaccine

A subunit vaccine is composed of______

Purified parts of the micro organism

Vaccines present anti-bodies from a pathogen to stimulate immunity true or false

False

Which of the following is produced by cytotoxic T cells

Perforin, which makes holes in the cell membrane of infected cells

Which of the following is produced by cytotoxic T cells

Perforin, which makes holes in the cell membrane of infected cells

Which of the following is true regarding infected cells

They display peptide fragments of degraded viral proteins on their cell serface

Which of the following is produced by cytotoxic T cells

Perforin, which makes holes in the cell membrane of infected cells

Which of the following is true regarding infected cells

They display peptide fragments of degraded viral proteins on their cell serface

Cytotoxic T cells recognize_____

Viral antigens and class 1 MHC

Cytotoxic T cells produce cytotoxins which cause apoptosis in infected cells

True

Name the proper sequence in which they occurred during inflammatory response

Neutrophils roll along endothelium


Integrin activation


Margination

During the inflammatory response_____ degranulation and release_____

Mast cells; histamine

Which of the following terms describe the migration of neutrophils from blood vessels

Extravasation

The inflammatory response is a specific defense mechanism that the body initiates against tissue damage


True or false

False

Endothelial cells display selectins which bind to the integrins of neutrophils


True or false

True

Which of the following are antigen presenting cells

Macrophages and B cells

Helper T cells interact with target cells by recognizing______

Antigen-MHC protein complexes

Helper T cells interact with target cells by recognizing______

Antigen-MHC protein complexes

Helper T cell secrete_____To stimulate the proliferation of B cells

Cytokines

Helper T cells only interact with class 1 major histocompatibility complex (MHC) proteins


True or false

False

Plasma cells are B cells that produce antibodies true or false

True

Name all the adaptive immunity types of cells

B lymphocytes, T lymphocytes, antigen presenting cells, cytotoxic T cells, helper T cells, memory T cells, CD4 + cells, plasma cells

Name all the adaptive immunity types of cells

B lymphocytes, T lymphocytes, antigen presenting cells, cytotoxic T cells, helper T cells, memory T cells, CD4 + cells, plasma cells

Name all the nonspecific defense cells

Neutrophils

Name the five things associated with adaptive immunity

Vaccines, agglutination, memory, clonal selection, third line of defense

Name the three things associated with nonspecific defense

Acid mantle, first line of defense, second line of defense

Name 4 characteristics T cells

Can produce lethal hits to infected self-cells


Include helper cell lines


Direct activation produced by MHC-1 recognition


Mature from thymic tissues

Name 4 characteristics of B cells

Differentiate into plasma cells when activated


Anti-body mediated immunity


Direct activation produced by MHC-2 recognition


IgG and IgM formation in the secondary immune response

Name 2 characteristics in both B cells and T cells

Produces memory cells


Arise originally from bone marrow

Four Cardinal signs of _____ are recognized.

Inflammation

Four Cardinal signs of _____ are recognized.

Inflammation

Erythrocytes arriving at the site and perfuming the dermis are visible trough the skin, which produces _____

Redness

The increase in blood flow and leafiness of capillaries, fluids are delivered to the tissue faster than they are removed, resulting in _____

Swelling (edema)

Swelling increases the pressure of fluids on adjacent mechanical structures. This activates receptors for_____.

Pain

Interesting ______ do not directly attacking nor destroy any pathogens

Antibodies

Interesting ______ do not directly attacking nor destroy any pathogens

Antibodies

This opens binding sites and promotes _______ resulting in a conversion of complement proteins to fight the pathogen

Complement fixation

Anti-bodies that bind to more than one cell simultaneously can rapidly cause_______ to occur which is a clumping that prevents the pathogen from contacting in damaging human cells

Agglutination

What is an example of the process that makes the molecule in soluble and less mobile

Precipitation

Antibodies______ to pathogens and in doing so render them in capable of causing an immune response

Bind

The first and second lines of defense are considered nonspecific resistance while the third line of defense is considered adaptive immunity


True or false

True

Discharge enzymes into a cloud of bactericidal chemicals

Neutrophils

Discharge enzymes into a cloud of bactericidal chemicals

Neutrophils

Guard against parasites and allergens

Eosinophils

Transform into Phagocytic macrophages that ingest dead pathogens

Monocytes

Include NK cells which patrol the body looking for diseased host cells

Lymphocytes

Secrete histamine increasing blood flow

Basophils

Name two things that are true about memory cells

Memory cells respond to antigens more rapidly than naïve T cells


Upon re exposure to a pathogen, memory cells engage in the T cell recall response destroying the pathogen quickly

Name two things that are true regarding memory in humoral immunity

Memory B cells are found mainly in the lymph nodes. Plasma cells form within hours creating a response so rapid that no noticeable signs of an illness appear

What is one thing that accurately describes the difference between cellular and Humoral immunity

Cellular immunity directly attacks pathogens and infected cells while humoral immunity releases anti-bodies to do so