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6 Cards in this Set
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- Back
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- Typically provide the eight standard hematology parameters (complete blood count [CBC]), plus a three-part, five-part, or six-part differential leukocyte count in less than 1 minute on 200 mL or less of whole blood |
Hematology Analyzers |
Automation - Allows more efficient workload management and more timely diagnosis and treatment of disease |
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Two basic principles of operation in Hematology Analyzers |
1. Electronic Impedance (resistance) 2. Optical Scatter |
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- Cell counting is based on the detection and measurement of changes in electrical resistance produced by cells as they traverse a small aperture |
Electronic Impedance |
- Cells suspended in an electrically conductive diluent such as saline are pulled through an aperture (orifice) in a glass tube - In the counting chamber, or transducer assembly, low-frequency electrical current is applied between an external electrode (suspended in the cell dilution) and an internal electrode (housed inside the aperture tube) - Electrical resistance between the two electrodes, or impedance in the current, occurs as the cells pass through the sensing aperture, causing voltage pulses that are measurable (Figure 12.1) |
