Understanding oxygen supply and demand while working in the health care field is essential. The tissue cell mitochondria need to have adequate oxygen for metabolic consumption and ATP production. There are limited means of oxygen storage in the tissues; as such a continuous supply of oxygen is required. The respiratory and cardiovascular systems work together to make sure oxygen is delivered throughout the body, and that these continuous requirements are met. Exploring the main role of the…
Furthermore, high-velocity perfusion due to minimal dilatation of the terminal segments of the spiral arteries leads to hydrodynamic stress in the intervillous space. This placenta stress stimulates the release of a number of factors derived from the trophoblast, and these factors, in turn, contribute to the widespread multisystemic maternal inflammatory response observed in preeclampsia (Tjoa, Levine and Karumanchi, 2007). Such placental-derived factors comprise of the anti-angiogenic proteins,…
Categories of function or problems Normal Function • Functioning Nerves and innervation from brain to organs to sense pH changes • Functioning Renal System • Functioning Respiratory System • Functioning buffering system • Concepts o Perfusion o Oxygenation o Elimination o Nutrition o Fluid and electrolyte balance Problems • Metabolic Acidosis: caused by loss of bicarbonate or too much acid in the body • Metabolic Alkalosis: caused by increase in bicarbonate or loss of acid in the body…
being admitted to the telemetry unit, her lab values and urinary output revealed that she had sustained an acute kidney injury due to the decreased cardiac output and perfusion from the supraventricular tachycardia episode. The nurse continued to assess for any changes that could indicate further decreased renal function and perfusion to the kidney. The patient was educated about the importance of a low sodium diet and to monitor for returning chest pain or shortness of…
The shortage of transplantable donor organs has profound consequences, especially for patients with end-stage lung disease, for which transplantation remains the only definitive treatment. Although advances in ex vivo lung perfusion have enabled the evaluation and reconditioning of marginally unacceptable donor lungs, clinical use of the technique is limited to ~6 h. Extending the duration of extracorporeal organ support from hours to days would enable longer recovery and recipient-specific…
managed in the initial minutes of encounter: if ventilatory effort is compromised, intubation and initiation of mechanical ventilation is indicated ○ Intravenous fluids and pharmacologic therapy (i.e., pressor agents) to sustain adequate tissue perfusion at a mean arterial pressure of 110 mm Hg…
In in situ heart perfusion, the heart is disconnected from any physiological influence, including adrenergic and cholinergic receptors, while it is still intact and protected inside the pericardial cavity and directly infused with physiological saline solution. Considering…
said to be a major cause of hypertension associated with preeclampsia. Incomplete trophoblastic invasion of the uterine spiral arteries results in failure to transform from thick-walled muscular vessels to saclike flaccid vessels. Placental hypo-perfusion, caused by the incomplete invasion leads to the release of systemic vasoactive compounds that results in an exaggerated inflammatory response, vasoconstriction, capillary leak, hypercoagulability, platelet dysfunction and endothelial damage…
Cardiac magnetic resonance (CMR) is a non-invasive radiological technique used for evaluating the heart providing details about its structure and functions. CMR has gained a lot of clinical application over the years as it provides high image quality and precision. The advantages of CMR over other imaging modalities include the high natural contrast between the intravascular blood pool and the intracardiac blood pool it provides, lack of ionizing radiation, and its three-dimensional imaging…
The alveolus also have spores that dispute air along the alveolus. The alveolus walls are thin to allow gas exchange to occur quickly. Quick check 25-2 1-2 1. The major components of the pulmonary circulation are ventilation, gas transport and perfusion to the lungs.…