• Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key

image

Play button

image

Play button

image

Progress

1/12

Click to flip

12 Cards in this Set

  • Front
  • Back
TNF-alpha is produced by which group of T-cells?
T-helper 1 (Th1) cells
What 4 other cytokines does TNF-alpha produce?
1) IL-1
2) IL-2
3) G-CSF
4) IFN-gamma
Name the 3 TNF-apha inhibitors
1) Etanercept
2) Infliximab
3) Adalimumab
What is the trade name for Etanercept?
Enbrel
What is the trade name for Infliximab?
Remicade
What is the trade name for Adalimumab?
Humira
Which 2 TNF-alpha inhibitors are fully human?
Etanercept (Enbrel) and Adalimumab (Humira)
This TNF-alpha inhibitor has the highest risk of developing anti-drug antibodies
Infliximab (Remicade)
Which TNF-alpha inhibitor is a Chimeric (25% mouse, 75% human) monoclonal IgG antibody?
Infliximab (Remicade)
Which TNF-alpha inhibitor is fully human fusion protein that binds to both TNF-alpha AND TNF-beta?
Etanercept (Enbrel)
Which TNF-alpha inhibitor is a fully human monoclonal IgG antibody that binds to TNF-alpha only?
Adalimumab (Humira)
Which TNF-alpha inhibitor is a chimeric IgG monoclonal antibody specific for TNF-alpha only?
Infliximab (Remicade)