Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
34 Cards in this Set
- Front
- Back
|
How large are WBC's and what do they fight against?
|
Larger than RBC's and fight against pathogens.
|
|
|
What are the two types of WBC's?
|
agranule and granule
|
|
|
What are the 5 types of WBC's
|
neutrohil, eosinophil, basophil, lymphocyte, monocyte.
|
|
|
What is the volume of WBC's per microliter?
|
5-10K
|
|
|
What does a high WBC count indicate?
|
leukocytosis
|
|
|
What does a low WBC count indicate?
|
leukopenia
|
|
|
what does the nucleus of a neutrophil look like?
|
2-5 lobes or more lobes connected by threads.
|
|
|
What does the eosinophil nucleus look like?
|
bi-lobed looks like headphones
|
|
|
What does the nucleus of the basophil look like?
|
Very large varied in shape; generally obscured by large granules
|
|
|
What does the nucles of lymphocytes look like?
|
Large, round, or slightly indented nucleues that stains very dark purple.
|
|
|
what does the nucleus of a monocyte look like?
|
Large kidney bean or horseshoe-shaped; sometimes oval and indented.
|
|
|
What are the respective percentages of all the 5 types of WBC's in preferential order: Neutrophil, eosinophil, basophil, lymphocyte, monocyte.
|
60-70%, 2-4%,0.5-1%,3-8%, 20-25%
|
|
|
What does a high count of neutrophils indicate?
|
Bacterial infection, burns, stress, inflammation
|
|
|
" low "?
|
Radiation exposure, drug toxicitiy, vitamin B12, deficiency, systemic lupus erythematosus
|
|
|
What does a high count of lymphocytes indicate?
|
viral infections, some leukemias
|
|
|
" low "?
|
prolonged illness, immunosuppression, treatment with cortisol.
|
|
|
What does a high count of monocytes indicate?
|
Viral or fungal infections, tuberculosis, some leukemias, other chronic diseases.
|
|
|
" low "?
|
Bone marrow depression, treatment with cortisol.
|
|
|
What does a high count of eosinophils indicate?
|
Allergice reactions, parasistic infections, autoimmune diseases
|
|
|
" low "?
|
Drug toxicity, stress
|
|
|
What does a high count of basophils indicate?
|
Allergic reactions, leukemias, cancers, hypothyroidism.
|
|
|
" low "?
|
Pregnancy, ovulation, stress, hyperthyrodism.
|
|
|
What do neutrophils use to destroy disease causing microbes?
|
Phagocytosis
|
|
|
What is the function of the eosinophil?
|
decrese effects of histamine in the inflammatory response and during allergic reactions.
|
|
|
What infections do the eosinophil's help fight?
|
parasitic
|
|
|
What are the basophils involved in?
|
Inflammatory and allergic reactions
|
|
|
What do the basophils secrete?
|
histamine (mediator of inflammation) or heparin (anticoagulant)/prevents blood clotting.
|
|
|
What are the three major subtypes of lymphocytes?
|
B cells, T cells, Natural Killer Cells
|
|
|
Antibody mediated (humoral) immunity. Destroy bacteria and bacterial toxins; convert into Plasma cells which produce (ab)
|
B cells
|
|
|
Cell mediated immunity. destroy viral infected cells, fungi, transplan cells, cancer cells and some bacteria. Responsible for transfusion reactions, transplant rejection and some allergies.
|
T Cells
|
|
|
Destroy a wide variet of infectious microbes.
|
Natural Born Killers
|
|
|
what do monocytes when emigrated from the blood stream to a damaged site enlarge into?
|
macrophages
|
|
|
What process do monocytes begin at that point?
|
phagocytosis or cellular debris and foreign agents.
|
|
|
What are monocytes most common in?
|
chronic infections.
|
