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27 Cards in this Set
- Front
- Back
vitamin A deficiency
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night blindness, rash, dry eyes, increased infection. vitamin A is a fat soluble vitamin
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vitamin A intoxication
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teratogenic (be careful in pregnancy! - isotretinoin taken for acne is a vitamin A analog), thick bones, pseudotumor cerebri
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Vitamin C deficiency
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results in scurvy: hemorrhages, skin petechiae, bone issues, gum issues, loose teeth, gingivitis, pour wound healing, bone pain (due to periosteal hemorrhage). pt on tea and toast or hot dog and soda diet that presents with bleeding gums and bone pain.
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Vitamin D deficiency
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rickets, osteomalacia, hypocalcemia. vit D aids absorption of Ca from gut. Fat soluble vitamin
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Vit D intoxication
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hypercalcemia, nausea, renal issues
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Vit E deficiency
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Anemia, peripheral neuropathy, ataxia. fat soluble vitamin
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Vit E intoxication (infants)
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NEC
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Vit K deficiency
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bleeding, increased PT (Extrinsic). fat soluble vitamin. vit K is given to all newborns to prevent hemorrhagic dz. needed for synthesis of clotting factors 2, 7, 9, 10, C, S. may see vit K deficiency with abx that kill normal GI flora that synthesize vit K.
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Vit K intoxication
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hemolysis, leading to kernicterus (I'm guessing in the newborn?)
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Vit B1 deficiency
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thiamine. may see wet beri beri, which is high out put cardiac failure. may also see dry beri beri, which is peripheral neuropathy. may also see wernicke and or korsakoff syndromes. commonly seen in alcoholics
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Vit b2 deficiency
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riboflavin. cheilosis, angular stomatitis, dermatitis
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Vit B3 deficiency.
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dermatitis, dementia, diarrhea. also stomatitis.
AKA pellagra. niacin |
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Vit B6 deficiency
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pyridoxine. peripheral neuropathy, cheilosis, stomatitis, convulsions (infant), microcytic anemia, seborrheid dermatitis.
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vit B12 deficiency
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cobalamin. megaloblastic anemia and neurologic sx. common cause is pernicious anemia (antiparietal cell antibodies, so parietal cells can't secrete IF). associ with other autoimmune conditions, schilling test will dx cause.
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folate deficiency
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megaloblastic anemia without neurologic sx
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iron deficiency
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microcytic anemia, koilonychia
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iron overload
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aka hemochromatosis
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iodine deficiency
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goiter, cretinism, hypothyroid
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iodine excess
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myxedema
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zinc deficiency
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decreased taste, rash, slow wound healing
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Cu deficiency
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menke's disease x-linked, kinky hair, MR
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CU toxicity
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wilson's
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Selenium deficiency
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cardiomyopathy, muscle pain
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selenium toxicity
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lose hair, nails
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chromium deficiency
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impaired glucose tolerance
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what is the most classic iatrogenic cause of B6 deficiency
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prolonged treatment with INH. should co-prescribe this vitamin along with INH
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list three meds that cause folate deficiency
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phenytoin
methotrexate TMP |