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23 Cards in this Set

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Polyhedral (Viral Shape)

High Symmetry


Icosahedron 20 faces, 12 corners


Examples: Rhinovirus, Epstein-Barr virus (Mononucleosis), and herpes

Virus Composition

Nucleic Acid - Dna or Rna


Capsid- Protein Coating surrounding nucleic acid


Envelope-lipids proteins, carbohydrates


May have spikes- carbs and proteins


Envelope may increase binding ability to host

Central Dogma

Sdescribes flow of genetic information within a cell, followed by prokaryotes and eukaryotes.

Viral Shape (Helical)

Shape refers to nucleocapsid doesn't matter if enveloped or not


Rod Shaped stacking together=Helical


Examples. Ebola,flue,rabies

Viral Shape ( Complex)

Head and tail components or other complexities


Common bacteriophage has polyhedral head, tail sheath and tail fibers


examples: smallpox virus, orthopoxvirus

Viral Species

A group of viruses sharing the same genetic information and ecological niche (host)

Lytic Cycle (Bacteriophage replication)

ends with lysis and death of host cell

Lysogenic cycle

host cell remains alive

Varicella zoster Virus (HHV-3)

Herpes virus family


Mild Childhood disease


3rd most common infectious disease after gonorrhea & chlamydia until 1995 vaccine


Enteres respiratory localizes in skin after 2 weeks skin forms vesicles which fill with pus,rupture

Epstein-Barr virus (HHV-4)

Infectious mononucleosis


Characterized by proliferation of monocytes


Childhood infections are asymptomatic


S&S- fever, sore throat, swollen lymph nodes in the neck general weakness

Cytomegalovirus (HHV-5)

Cytomegalovirus Infections


Infected cells swell


Latent in white blood cells


May be asymptomatic or mild ( s&s similar to mono)


Small Pox virus ( Dna Enveloped)

Variola major - Mortality rate of 20% or higher


Variola minor - mortality rate of less than 1%


S&S - fever, aches, headache, vomiting, raised skin lesions

Mumps virus (Rna,Enveloped)

Infection of salivary glands


Respiratory droplet transmission


Virus multiplies in respiratory tract and neck lymph nodes


Ends up in blood stream then reach salivary glands


glands swell 16-18 after virus exposure

Parainfluenza virus (Rna, enveloped)

Bronchitis


Inflammation of the bronchi of the lungs


s&S - loud, harsh, barking cough labored breathing fever


croup in toddlers


Respiratory syncytial virus (Rs)


Rna virus, enveloped

Bronchitis, Common viral respiratory disease in infants.

Rubella virus ( German Measles)


Rna virus, enveloped

More mild than rubeola may go undetected, spots not

Rubeola Virus (Measles)


Rna virus enveloped

Extremely contagious, respiratory spread virus


10- 12 day incubation, fever common cold symptoms, small raised spots Kopliks spots in mouth= tiny red w/ white centers


Very dangerous in young and old pneumonia and secondary infections

Coronavirus Rna Virus, enveloped


(Rhinitis)

Nasal inflammation,

Influenza Virus


Rna virs, enveloped

Hemagglutin(H) spikes to recognize and attach to body cells


Neuraminidase (N) spikes help virus escape from cell after intracellular reproduction


8 types of rna

Rabies Virus


Rna Virus, enveloped

Virus multiplies in skeletal muscles and then travels along pns to cns causing encephalitis


Rabies virus ( Furious Rabies)

l

Norovirus Rna, Non envelope

90% viral gastroenteritis from rota-& norovirus


Enviromentally hardy


Spread throughout daycares, cruise ships, etc.



Rotavirus Rna virus non enveloped

Most common cause of gastroenteritis


3 million cases but fewer than 100 deaths per year in us