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18 Cards in this Set
- Front
- Back
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African Swine Fever
-clinically indistinguishable from |
-Classical Swine Fever
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African Swine Fever
-morphology characteristics |
-enveloped
-dsDNA |
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African Swine Fever
-genus -family |
-genus: Asfivirus
-family: Asfaviridae (african swine fever and related viruses) |
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African Swine Fever
-resistance characteristics |
-environmental inactivation resistance
-survive months in meat |
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African Swine Fever
-susceptibility characteristics |
-cook meat to 60C for 30 min
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African Swine Fever
-hosts -reservoir |
-hosts: warthogs, bush pigs, giant forest hogs, domestic hogs, feral hogs, wild hogs
-reservoirs: african hogs, soft ticks (ornithodoros) |
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African Swine Fever
-vector |
-Ornithodoros (soft tick)
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African swine Fever
-distribution |
-foreign in US
-enxootic in sub-saharah africa and Sardinia (italy) -all over europe, africa, south america |
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African Swine Fever
-transmission |
-pig-to-pig blood contact/bloody exudate
-uncooked meat scrap feeding in Russia -Ornithodoros (soft tick) |
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Only DNA arbovirus
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-African Swine Fever
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African Swine Fever
-pathogenesis |
-replication in macrophages in LNs near point of entry
-Viremia (4-8 days) -secondary wave of replication in lymphoid tissue, endothelium, lung, spleen, kidney -death/inhibition of monocytes and lymphocytes --> lost immune function -no neutralizing antibodies develop -vasculitis and thrombocytopenia cause hemorrhage |
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African Swine Fever
-clinical signs |
-anorexia
-fever -leukopenia -cyanosis -petechiae -ecchymoses of skin -prolonged bleeding from needle wounds |
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African Swine Fever
-gross lesions |
-widespread hemorrhage (LNs, kidneys, alimentary tract)
-severe pulmonary edema -fluid in pleural and pericardial spaces (not in classical swine fever) -enlarged spleen (not in classical swine fever) |
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African Swine Fever
-immunity |
-neutralizing antibodies aren't produced
-remain infected for months-life -no field vaccines |
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African Swine Fever
-first mode of action in diagnosis |
-make sure to call state vet if expected because it is a foreign animal disease
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African Swine Fever
-preferred diagnostic specimens |
-Blood in EDTA tube
-spleen -LNs -tonsils -kidney |
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African Swine Fever
-differential diagnoses |
-Classical Swine Fever (Hog Cholera)
-Porcine Dermatitis and Nephropathy Syndrome (PDNS) -Salmonellosis -Erysipelas -Pseudorabies |
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African Swine Fever
-prevention and control |
-restrict importation of pigs and uncooked pork
-incinerate all pork waste -slaughter infected/exposed animals in infected areas |
