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57 Cards in this Set
- Front
- Back
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Hep A
family? nucleic acid? |
picornavirus family
+ ss RNA |
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Hep A
transmission? chronic carrier? capsid or envelope? |
fecal-oral
not chronic carrier capsid |
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Another name for Hep A?
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infectious hep
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Hep B
family? nucleic acid? |
hepadnavirus
ds DNA |
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Hep B
transmission? chronic carrier? capsid or envelope? |
parenteral
chronic carrier envelope |
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Is Hep B envelope ether resistant, low pH resistant, and resistant to heat or freezing?
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yes
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Another name for Hep B?
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serum hep
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What is most common cancer in the world?
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hepatocellular carcinoma from hep B
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What does Hep B have that allows it to transform host cells?
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reverse transcriptase
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Hep C
family? nucleic acid? |
flavivirus
+ ss RNA |
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Hep C
chronic carrier? capsid or envelope? |
chronic carrier
envelope |
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Is Hep C usually subclinical?
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yes
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What is the leading cause of chronic hepatitis?
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hep C
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What is another name for Hep C?
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non-A, non-B post-transfusion hepatitis
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Hep D
nucleic acid? chronic carrier? capsid or envelope? |
- ss RNA
chronic carrier envelope |
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What does Hep D need to cause infection?
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Hep B
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What is Hep D's route of transmission? (2)
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parenteral or sexual
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Hep E
family? nucleic acid? chronic carrier? envelope or capsid? |
calicivirus
+ ss RNA not chronic carrier capsid |
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Hep E
transmission? associated with pandemics? |
fecal oral
yes |
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Hep E: who has the highest mortality?
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pregnant women in 3rd trimester
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Herpesvirus family
nucleic acid? |
ds DNA
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What are 3 prodromal symptoms of HSV-1?
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tingling of lips, malaise, fever
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Most viral diseases from prodrome to resolution are how long?
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7-14 days
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What are 5 members of herpes family?
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HSV-1
HSV-2 VZV CMV EBV |
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HSV-1: above or below waist?
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above
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HSV-2: above or below waist?
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below
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What causes hairy leukoplakia on lateral borders of tongue?
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EBV
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What is the largest virus of all?
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pox (smallpox)
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What ds DNA virus replicates in cytosol?
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pox
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HPV
nucleic acid? envelope or capsid? |
ds DNA
capsid |
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adenovirus
nucleic acid? envelope or capsid? |
ds DNA
capsid |
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parvovirus
nucleic acid? envelope or capsid? common disease? |
ss DNA
capsid B-19 causes Fifth Disease |
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all picornaviruses
nucleic acid? envelope or capsid? |
+ ss RNA
capsid |
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What are 4 members of picornavirus and what do they cause?
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polio (polio)
cocksackie (HFAM, herpangina) rhino (cold) heparna (hep A) |
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Picornavirus receptors are members of what family of host genes?
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immunoglobulin superfamily (ICAM, etc)
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What is the cap on the poliovirus genome (mRNA)?
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VpG
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How are poliovirus proteins made?
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one large polyprotein is transcribed and then cut into individual proteins
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What does rhinovirus bind to and is it acid resistant?
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ICAM-1; no, it's acid labile
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Calicivirus family
nucleic acid? envelope or capsid? example of a species? |
+ ss RNA
capsid norovirus (norwalk) |
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How many noroviruses (calicivirus) are needed to cause infection?
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as few as 10
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Corona virus
nucleic acid? envelope or capsid? example of species? |
+ ss RNA
envelope SARS |
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Influenza
nucleic acid? envelope or capsid? |
- ss RNA
envelope |
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What do Zanamivir and Oseltamivir target?
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NA (release of virions)
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What do Amantidine and Rimantidine target?
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matrix proteins on Type A only!
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What type(s) of influenza undergo shift?
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only Type A
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Reoviridiae
nucleic acid? envelope or capsid? special trait? example of species? |
ds-RNA
capsid double capsid (double;double) rotavirus |
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What does rotavirus cause and what family of virus is it?
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infantile diarrhea; reoviridiae
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HIV
nucleic acid? envelope or capsid? |
+ss RNA
envelope |
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What is the host cell receptor for M type HIV?
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CCR5
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What is the host cell receptor for T type HIV?
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CXCR4
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What family and species is HIV?
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family; retrovirus
species; lentivirus |
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What is the progress of HIV/AIDS in 4 basic steps?
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1. 2-3 weeks acute HIV
2. until 6 weeks is recovery and seroconversion 3. asymptomatic stage 4. AIDS |
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What are 3 components of the cell wall of C. albicans?
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glucans, mannans, chitins
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Describe the genome of C. albicans.
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diploid with 8 chromosomes
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What are 2 virulence factors of C. albicans?
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adhesion and phenotype switching
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What are 2 polyenes, and what do they target and have as a side-effect?
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amphotericin and nystatin
target cell membrane but are nephrotoxic |
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What do azoles target and what is a side effect?
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ergosterol synthesis in fungal cell wall; they are hepatotoxic
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