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96 Cards in this Set
- Front
- Back
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Only single stranded DNA virus |
Parvovirus |
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Only DNA virus with complex symmetry |
Poxvirus |
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Simplest DNA animal virus |
Parvovirus B19 |
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Slapped cheek syndrome or 5th disease in children Arthralgia and arthritis in adults |
Erythema infectiosum |
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Severe acute anemia resulting from abrupt cessation of RBC synthesis in the bone marrow |
Transient Aplastic Anemia |
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Viral infection on the 2nd trimester of pregnancy Causes fatal death |
Hydrops fetalis |
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A persistent infection and chronic suppression of bone marrow and chronic, severe anemia in immunocompromised patients |
Pure Red Cell Aplasia |
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Usually attacks the epithelial cells of the eye, the respiratory, gastrointestinal and urinary tracts |
Adenovirus |
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Nonenveloped, icosahedral viruses with DNA genome |
Adenovirus |
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Vectors for gene therapy approaches |
Adenovirus |
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Excellent models for molecular and biochemical studies of eukaryotic cell processes |
Adenovirus |
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Acute RTI in young children |
Type 1 2 5 6 |
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Acute RTI in adults |
Type 3 4 7 |
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10 to 20% childhood pneumonia |
Types 3 7 21 |
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Outbreak of severe respiratory disease |
Type 14 |
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Swimming pool conjuctivitis |
Types 3, 7 |
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Epidemic and highly contagious keratoconjunctivitis in adults |
Types 8, 9, 37 |
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Infantile gastroenteritis |
Types 40 and 41 |
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Acute hemorrhagic cystitis |
Types 11 and 21 |
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Large viruses with an icosahedral symmetry and a double stranded DNA genome Lifelong latent infections Diseases associated with primary infection and reactivated infection Cytopathic effects Controlled by T-cells |
Herpesviruses |
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HSV 1 HSV 2 VZV |
Alpha herpes |
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CMV |
Beta herpes |
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EBV HHV-6 HHV-7 HHV-8 BV |
Gamma herpes |
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Occurs in buccal and gingival mucosa of the mouth S/x: swollen, tender gums with vesicular lesions |
Gingivostomatis |
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"Fever blisters" or "cold sores" Milder, recurrent from crops at the border of the lips |
Herpes simplex labialis |
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"Herpitic keratitis" Dendritic keratitis or corneal ulcers or vesicles on the eyelids |
Keratoconjunctivitis |
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Sporadic fatal from encephalitis in US Necrotic lesions S/Sx: Fever, HA, vomiting, seizures and mental status |
Encephalitis |
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Pustular lesion of the skin |
Herpetic withlow |
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Bodies of wrestlers |
Herpes gladiatorum or Mat herpes |
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HSV-1 infection in persons with chronic eczema |
Eczema herpeticum |
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Associated with the STD form of herpes |
HSV 2 |
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Painful vesicular lesions of the male (penis) and female genitals and anal area |
Genital herpes |
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Contact with vesicular lesions within the birth canal |
Neonatal herpes |
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"Chicken pox" Mild in children, severe in adults Vesicular eruption of skin and mucous membrane fever Contagious during recovery fever |
Varicella Virus |
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"Shingles" Painful skin lesions innervated by a single sensory neuron |
Zoster Virus |
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Ubiquitous herpesvirus causing congenital infections |
Cytomegalovirus |
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Giant multinucleated cells |
Cytomegalovirus |
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Close person-to-person contact and by blood transfusion |
Cytomegalovirus |
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Virus is shed in urine, saliva, semen, breast milk, cervical secretions and in circulating WBCs |
Cytomegalovirus |
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Older children and adults |
CMV mononucleosis |
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Leads to pneumonia |
CMV infections |
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For life threatening CMV infections in immunocompromised hosts; CMV retinitis, esophagitis and colitis; controls progressive hearing loss in neonates |
Ganciclovir |
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Recommended tx for CMV retinitis |
Foscarnet |
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For bone marrow and transplant patients |
Acyclovir Valacyclovir |
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Ubiquitous herpesvirus targeting the B-lymphocytes |
Epstein Barr Virus |
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Transmitted by infected saliva and initiated infection in the oropharynx |
Epstein-Barr Virus |
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Treated with Acyclovir |
Epstein-Barr Virus |
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Causes "infectious mononucleosis" |
Epstein-Barr Virus |
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"Kissing disease" |
Epstein-Barr Virus |
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Associated with Cancer |
Epstein-Barr Virus |
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Seen in African children (tumor of the jaw) |
Burkitt's lymphoma |
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A cancer of epithelial cells and common in male chinese people |
Nasopharyngeal carcinoma |
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A wart like growth in tongue among AIDS patients |
Oral hairy leukoplasia |
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1st recognized in 1986 from peripheral blood mononuclear cells from patients with lymphoproliferative disorders |
Human Herpesvirus 6 |
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Interacts with human CD46 T-cells |
Human Herpesvirus 6 |
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Transmitted via oral secretion |
Human Herpesvirus 6 |
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Causing the 6th disease or "roseola infantum" or "exanthema subitum" |
Human Herpesvirus 6 |
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S/Sx are fever and skin rash |
Human herpesvirus 6 |
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Isolated in 1990 from activated T-cells recovered from peripheral blood lymphocytes of healthy individuals |
Human Herpesvirus 7 |
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Affects infants and children causing roseola infantum |
Human herpesvirus 7 |
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A new herpesvirus |
Human Herpesvirus 8 |
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"KSHV" (kaposi sarcoma-associated herpesvirus) |
Human Herpesvirus 8 |
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Kaposi's sarcoma |
Human Herpesvirus 8 |
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Transmitted by contact with oral secretions, sexual contact, blood transfusion, organ transplants and breast milk |
Human Herpesvirus 8 |
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Herpes B Virus of Old World Monkeys which is pathogenic for humans |
B virus |
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Monkey bite also by respiratory route or ocular splash exposure |
B Virus |
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Acute ascending myelitis and encephalomyelitis |
B Virus |
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Only RNA virus that is double stranded |
Reovirus |
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Naked RNA virus |
Reovirus Picornavirus Calicivirus |
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Large family with many members |
Picornaviruses |
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Small, non-enveloped (+) single single stranded RNA viruses |
Picornavirus |
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Transient inhabitants of human alimentary tract |
Entetoviruses |
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Primarily infects the enteric tract |
Enteroviruses |
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Optimally grown at 37C |
Enteroviruses |
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Stable under acid conditions |
Enteroviruses |
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Includes Poliovirus, Coxsackie virus, Echovirus |
Enteroviruses |
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Diffuses to the motor neurons of the lower limbs |
Poliovirus |
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Causes "poliomyelitis" |
Poliovirus |
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Febrile illness |
Mild poliomyelitis |
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Aseptic meningitis |
Nonparalytic poliomyelitis |
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Flaccid paralysis |
Paralytic poliomyelitis |
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Monkey kidney cultures; a killed vaccine that induces humoral immunity but not local intestinal immunity |
Salk Vaccine |
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Primary monkey, produces IgM and IgG in the blood |
Sabin vaccine |
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Aseptic meningitis (A7 and A9) |
Group A Coxsackie Virus |
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A severe febrile vesicular pharyngitis |
Herpangina |
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Oral and pharyngeal ulcerations and a vesicular rash of the palms and soles Diarrhea in children |
Hand, foot, mouth disease (A16) |
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Aseptic meningitis |
Group B Coxsackie virus |
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Bornholm disease Epidemic myalgia Devil's grip |
Pleurodynia |
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Myocarditis and pericarditis |
Pleurodynia |
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Fatal disease due to multiples organ infection (heart, brain, liver) |
Generalized disease of infants |
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Entero Cytopathogenic Orphan Viruses |
Echoviruses |
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Diseases are Acute Conjuctivitis (Enterovirus 70) Meningitis, encephalitis, paralysis, poliomyelitis and hand-foot-and-mouth-disease (Enterovirus 71) |
Echoviruses |
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Common cold virus |
Rhinoviruses |
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Isolated in nasal secretions |
Rhinoviruses |
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Grows better at 33 C, acid labile and readily mutate |
Rhinovirus |
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Transmitted through contaminated fingers |
Rhinovirus |
